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2-fluoro-adenine

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Identification
Molecular formula
C5H4FN5
CAS number
42211-93-6
IUPAC name
2-fluoro-7H-purin-6-amine
State
State

At room temperature, 2-fluoro-adenine is typically found in a solid state. It remains stable under normal conditions used in laboratory environments.

Melting point (Celsius)
217.00
Melting point (Kelvin)
490.15
Boiling point (Celsius)
408.15
Boiling point (Kelvin)
681.30
General information
Molecular weight
151.11g/mol
Molar mass
151.1250g/mol
Density
1.8000g/cm3
Appearence

2-Fluoro-adenine typically appears as a white to off-white crystalline powder. It is a solid at room temperature and can have a slightly bitter taste, though it is primarily handled in laboratory settings, not for sensory analysis. The crystalline nature may give it a shiny appearance under specific lighting conditions.

Comment on solubility

Solubility of 2-fluoro-7H-purin-6-amine

The compound 2-fluoro-7H-purin-6-amine, known for its intriguing chemical structure, exhibits specific solubility characteristics that are essential for its application in various fields. Understanding its solubility can be summarized as follows:

  • Water solubility: 2-fluoro-7H-purin-6-amine is considered to be sparingly soluble in water.
  • Organic solvents: The compound shows better solubility in organic solvents, including dimethyl sulfoxide (DMSO) and ethanol.
  • pH influence: Its solubility may also be affected by the pH of the solution, which can alter the ionization state and thus enhance its overall solubility.
  • Temperature effect: Increasing temperatures generally improve solubility; therefore, higher temperatures may facilitate the dissolution process.

In summary, while 2-fluoro-7H-purin-6-amine has limited water solubility, its favorable properties in organic solvents make it suitable for various applications in research and pharmaceuticals. Understanding these solubility dynamics is crucial for optimal usage and formulation strategies.

Interesting facts

Interesting Facts about 2-Fluoro-7H-purin-6-amine

2-Fluoro-7H-purin-6-amine, often referred to within the scientific community simply as 2-F-adenine, is a fascinating compound belonging to the purine family. This compound is not only critical in understanding various biological processes but also plays a significant role in pharmaceutical research.

Key Highlights:

  • Role in Nucleic Acids: Being a purine derivative, 2-fluoro-7H-purin-6-amine can be seen as a structural analog of adenine, a fundamental building block of DNA and RNA.
  • Fluorine Influence: The substitution of a fluorine atom can significantly alter the compound's properties, including its metabolic stability and interaction with biological targets.
  • Potential Antiviral Properties: Compounds like this one have been of interest in drug development, particularly for their potential effectiveness against viral infections.
  • Research Applications: Scientists often utilize derivatives of adenine in studies related to gene expression and cellular processes. This compound offers unique insights into the structural biology of nucleotides.

As a researcher, one may ponder the implications of manipulating such compounds. For example, the incorporation of fluorine could lead to enhanced selectivity of processes in which adenine is involved. “Understanding these modifications helps us unveil the intricacies of molecular interactions,” says a noted chemist.

In conclusion, 2-fluoro-7H-purin-6-amine is more than just a chemical structure; it is a bridge to understanding fundamental biological mechanisms and innovative therapeutic strategies.

Synonyms
2-Fluoroadenine
700-49-2
2-fluoro-7H-purin-6-amine
2-Fluoro-6-aminopurine
2-Fluoro-1H-purin-6-amine
2-Fad
1H-Purin-6-amine, 2-fluoro-
SRI 774
2-Fluoro-7(9)H-purin-6-ylamine
ADENINE, 2-FLUORO-
Purine, 6-amino-2-fluoro-
NSC 27364
BRN 0610958
F-Ade
2C8H3H4EBG
CHEBI:72457
NSC-27364
DTXSID80220264
NSC27364
9H-PURIN-6-AMINE, 2-FLUORO
FLUDARABINE PHOSPHATE IMPURITY D [EP IMPURITY]
FLUDARABINE PHOSPHATE IMPURITY D (EP IMPURITY)
FLUDARABINE PHOSPHATE IMPURITY, 2-FLUOROADENINE-(USP IMPURITY)
FLUDARABINE PHOSPHATE IMPURITY, 2-FLUOROADENINE-[USP IMPURITY]
Adenine, 2-fluoro-(VAN)
DTXCID80142755
1H-Purin-6-amine, 2-fluoro-(9CI)
624-159-6
2-fluoro-9h-purin-6-amine
6-Amino-2-fluoropurine
Fluoroadenine
MFCD01632749
TCMDC-124283
EDDHSA
C5H4FN5
UNII-2C8H3H4EBG
Adenine, 2-fluoro- (VAN)
a,a'-(1,2-Ethanediyldiimino)bis[2-hydroxy-5-sulfo-benzeneacetic Acid; N,N-Ethylenebis[2-(2-hydroxy-5-sulfophenyl)glycine; N,N'-Ethylenebis[2-(2-hydroxy-5-sulfophenyl)glycine
A2F
2-Fluoroadenine, 96%
9H-Adenine, 2-fluoro-
SCHEMBL8850
6-Amino-2-fluoro-9H-purine
CHEMBL580404
BCP20080
BBL102193
STL454963
STL555992
AKOS005063499
AKOS005257768
AKOS006223977
CS-W008469
FF05946
HY-W008469
MB08365
PS-6414
AC-15593
PD131035
SY036850
DB-021114
F0647
2-Fluoro-6-aminopurine;6-Amino-2-fluoropurine
2-Fluoro-7H-purin-6-amine (2-Fluoroadenine)
EN300-697497
Q27139933
Z1198269560
FLUDARABINE PHOSPHATE IMPURITY, 2-FLUOROADENINE- [USP IMPURITY]
InChI=1/C5H4FN5/c6-5-10-3(7)2-4(11-5)9-1-8-2/h1H,(H3,7,8,9,10,11