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2-fluoro-N-(2-nitrophenyl)acetamide

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Identification
Molecular formula
C8H7FN2O3
CAS number
71556-22-0
IUPAC name
2-fluoro-N-(2-nitrophenyl)acetamide
State
State

At room temperature, 2-fluoro-N-(2-nitrophenyl)acetamide is typically in a solid state. The compound forms crystalline solids that are stable under normal conditions.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
301.00
Boiling point (Kelvin)
574.15
General information
Molecular weight
198.16g/mol
Molar mass
198.1590g/mol
Density
1.4010g/cm3
Appearence

2-Fluoro-N-(2-nitrophenyl)acetamide typically appears as a solid crystalline compound. The crystals may exhibit a yellowish to off-white color due to the nitro group present in the structure, which can impart a slight hue.

Comment on solubility

Solubility of 2-fluoro-N-(2-nitrophenyl)acetamide

The solubility of 2-fluoro-N-(2-nitrophenyl)acetamide is an intriguing subject, highlighting its unique chemical structure and interactions within solvents. Understanding its solubility can help predict its behavior in various environments, including biological systems.

Key points about the solubility of this compound:

  • Polarity: 2-fluoro-N-(2-nitrophenyl)acetamide features polar functional groups, which suggest that it may have good solubility in polar solvents like water.
  • Hydrogen bonding: The presence of the acetamide group can engage in hydrogen bonding, potentially enhancing its solubility.
  • Competing factors: The fluorine substituent can both stabilize and destabilize interactions with solvents, complicating its solubility profile.

In summary, while one might expect some degree of solubility due to polar characteristics and hydrogen bonding potential, the overall solubility of 2-fluoro-N-(2-nitrophenyl)acetamide is characterized by a delicate balance of competing interactions. As with many compounds, empirical testing is crucial to determine its precise solubility in specific solvents.

Interesting facts

Interesting Facts About 2-Fluoro-N-(2-nitrophenyl)acetamide

2-Fluoro-N-(2-nitrophenyl)acetamide is a unique compound that has garnered attention for its intriguing chemical properties and potential applications. Here are some engaging insights:

  • Pharmaceutical Significance: This compound is part of a class of molecules that are often researched for their medicinal properties. Its structural components suggest potential as an inhibitor in various biochemical pathways, making it a candidate for drug development.
  • Fluorine Substitution: The incorporation of a fluorine atom is significant. Fluorination often enhances the biological activity of compounds, influencing their interaction with biological targets. This feature is a crucial focus in medicinal chemistry.
  • Nitro Group Activity: The presence of a nitro group in the para position can contribute heavily to the compound's reactivity. Nitro groups are known for their role in facilitating electron-withdrawing effects, which can enhance the compound’s electrophilicity.
  • Versatile Applications: Beyond pharmaceuticals, 2-fluoro-N-(2-nitrophenyl)acetamide has potential utilizations in fields such as agrochemicals or material sciences, where modifications to the acetamide framework can lead to novel compounds with tailored properties.
  • Research Opportunities: The synthesis and modification of 2-fluoro-N-(2-nitrophenyl)acetamide present numerous scholarly avenues. From studying its reactivity patterns to exploring its application in synthesis of more complex molecules, there is much to investigate in both academic and industrial settings.

In summary, 2-fluoro-N-(2-nitrophenyl)acetamide is a compound rich in potential, with multiple aspects waiting to be explored in the world of chemistry. Its significance stretches across various applications, making it a must-study for students and researchers alike.

Synonyms
2-Fluoro-2'-nitroacetanilide
3435-75-4
BRN 2115220
ACETANILIDE, 2-FLUORO-2'-NITRO-
DTXSID80187924
DTXCID40110415