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2-fluoro-N-(2,2,2-tribromo-1-hydroxy-ethyl)acetamide

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Identification
Molecular formula
C4H4Br3FNO2
CAS number
136093-39-3
IUPAC name
2-fluoro-N-(2,2,2-tribromo-1-hydroxy-ethyl)acetamide
State
State
This compound exists as a solid at room temperature.
Melting point (Celsius)
113.50
Melting point (Kelvin)
386.70
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
343.83g/mol
Molar mass
343.8250g/mol
Density
2.8700g/cm3
Appearence

The compound is typically a crystalline solid with a slightly off-white color, often appearing as a fine powder.

Comment on solubility

Solubility of 2-fluoro-N-(2,2,2-tribromo-1-hydroxy-ethyl)acetamide

The solubility of 2-fluoro-N-(2,2,2-tribromo-1-hydroxy-ethyl)acetamide can be considered through various factors that influence its behavior in different solvents. Understanding these factors can provide insight into the compound's practical applications and interactions.

Factors Influencing Solubility

  • Polarity: The presence of functional groups such as the fluorine atom and hydroxy group may impart polar characteristics, affecting solubility in polar solvents like water.
  • Hydrophobic Interactions: The tribromo and ethyl components contribute hydrophobic nature, which may limit solubility in water while enhancing solubility in organic solvents.
  • Hydrogen Bonding: The hydroxy group can engage in hydrogen bonding, potentially enhancing solubility in polar solvents.

In general, one might expect:

  • The compound may demonstrate moderate solubility in polar solvents due to the hydrogen bonding capability.
  • It may show higher solubility in nonpolar organic solvents, where the hydrophobic regions of the molecule can interact more favorably.
  • A quantitative evaluation would be necessary to determine specific solubility metrics in various solvents.

To summarize, the solubility of 2-fluoro-N-(2,2,2-tribromo-1-hydroxy-ethyl)acetamide is influenced by a balance between its polar and nonpolar characteristics, making it essential to consider the solvent choice for desired applications.

Interesting facts

Interesting Facts about 2-fluoro-N-(2,2,2-tribromo-1-hydroxy-ethyl)acetamide

2-fluoro-N-(2,2,2-tribromo-1-hydroxy-ethyl)acetamide is a fascinating chemical compound with applications across multiple fields, particularly in pharmaceuticals and agrochemicals. Here are some intriguing insights:

  • Fluorination Significance: The presence of the F atom plays a crucial role in the compound's biological activity and potential medicinal applications. Fluorinated compounds often exhibit increased metabolic stability and enhanced lipophilicity, which can lead to improved efficacy in drug formulation.
  • Tribromo Group: The addition of the Br atoms contributes to potent biological activity. Tribromo compounds have drawn interest in studies related to their effects as antimicrobial agents and their role in various chemical reactions.
  • Hydroxyl Impact: The hydroxy group in this compound can act as a site for further chemical reactions, permitting interesting pathways for synthesis and functionalization. Hydroxy-substituted compounds have also shown enhanced solubility in polar environments, often proving beneficial during formulations.
  • Potential Applications: Depending on the synthesis and structure-activity relationships, this compound might be explored for use in herbicides, antifungal applications, or other biological activities, making it a compound of interest for researchers in agriculture and medicinal chemistry.
  • Safety Considerations: Brominated compounds have been studied for their environmental impact. Therefore, understanding the degradation pathways and toxicity is vital for the safe handling and application of this compound.

In summary, 2-fluoro-N-(2,2,2-tribromo-1-hydroxy-ethyl)acetamide is a compound rich in potential, thanks to its unique structural features and reactivity. As with many chemical species, further empirical research is required to unlock its full potential and explore new applications.

Synonyms
1187-66-2
2-fluoro-N-(2,2,2-tribromo-1-hydroxyethyl)acetamide
Bromal fluoroacetamide
BRN 1867393
ACETAMIDE,2-FLUORO-(N-(1-HYDROXY-2,2,2-TRIBROMO)ETHYL)-
DTXSID00922758
ACETAMIDE, 2-FLUORO-(N-(1'-HYDROXY-2',2',2'-TRIBROMO)ETHYL)-
2-Fluoro-N-(2,2,2-tribromo-1-hydroxyethyl)ethanimidic acid