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2-fluoro-N-(2,4,5-trichlorophenyl)acetamide

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Identification
Molecular formula
C8H5Cl3FNO
CAS number
78357-54-3
IUPAC name
2-fluoro-N-(2,4,5-trichlorophenyl)acetamide
State
State

At room temperature, 2-fluoro-N-(2,4,5-trichlorophenyl)acetamide is in a solid state characterized by its crystalline form and relatively high density.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
402.85
Boiling point (Kelvin)
676.00
General information
Molecular weight
242.49g/mol
Molar mass
242.4850g/mol
Density
1.5930g/cm3
Appearence

2-fluoro-N-(2,4,5-trichlorophenyl)acetamide appears as a white to off-white crystalline solid. Its appearance is typical for many organic amides and it may appear as powder or crystalline chunks.

Comment on solubility

Solubility of 2-fluoro-N-(2,4,5-trichlorophenyl)acetamide

The solubility of 2-fluoro-N-(2,4,5-trichlorophenyl)acetamide can be described as *moderate* to *low*, which is influenced by several factors:

  • Polarity: The presence of polar functional groups in the compound enhances its solubility in polar solvents such as water, although the hydrophobic character introduced by the trichlorophenyl moiety limits its overall solubility.
  • Temperature: As temperature increases, the solubility of many organic compounds, including this one, typically improves. Higher temperatures can break intermolecular forces and make it easier for the compound to dissolve.
  • Solvent choice: 2-fluoro-N-(2,4,5-trichlorophenyl)acetamide displays better solubility in organic solvents like acetone and ethanol, compared to water, owing to its larger non-polar structure.

In summary, while 2-fluoro-N-(2,4,5-trichlorophenyl)acetamide shows some solubility in polar solvents, its solubility is greatly affected by the solvent’s characteristics, temperature, and the compound's own molecular structure. For practical applications, it is essential to consider these attributes to effectively utilize this compound in various chemical processes.

Interesting facts

Interesting Facts about 2-Fluoro-N-(2,4,5-trichlorophenyl)acetamide

2-Fluoro-N-(2,4,5-trichlorophenyl)acetamide is a noteworthy compound that showcases the intricate interplay between chemical structure and biological activity. Here are some fascinating insights into this compound:

  • Unique Structure: The presence of both a fluoro group and multiple chlorine substitutions contributes significantly to its chemical behavior, stability, and reactivity.
  • Biological Relevance: Due to its structural characteristics, this compound is of interest in pharmacology and toxicology. It may exhibit biological activities that can influence various enzymatic processes.
  • Pesticide Applications: Compounds with similar substituent patterns have been investigated for their potential use as herbicides, fungicides, and insecticides, making them invaluable in agricultural chemistry.
  • Environmental Considerations: The halogenated nature of this compound raises discussions regarding its persistence in the environment and potential ecological impacts.
  • Research Potential: Scientists are encouraged to explore the properties of 2-fluoro-N-(2,4,5-trichlorophenyl)acetamide further. It poses interesting avenues for studies related to drug design and chemical synthesis.

In summary, 2-fluoro-N-(2,4,5-trichlorophenyl)acetamide highlights the synergy of halogenation in altering chemical properties and offers a glimpse into the significance of its usage in various scientific fields. As research continues to evolve, this compound stands as a testament to the complexities and marvels of modern chemistry.

Synonyms
2-Fluoro-2',4',5'-trichloroacetanilide
23595-40-6
BRN 2115448
ACETANILIDE, 2-FLUORO-2',4',5'-TRICHLORO-
DTXSID10178244
RefChem:315755
DTXCID40100735