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Fluoracetamide

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Identification
Molecular formula
C2H4FNO
CAS number
640-19-7
IUPAC name
2-fluoro-N-(4-fluorophenyl)-N-(2-hydroxyethyl)acetamide
State
State

Fluoracetamide is typically found in a solid state at room temperature, appearing as white crystals.

Melting point (Celsius)
106.00
Melting point (Kelvin)
379.00
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.00
General information
Molecular weight
151.12g/mol
Molar mass
151.1230g/mol
Density
1.3540g/cm3
Appearence

Fluoracetamide typically appears as a white crystalline solid. Its appearance may vary slightly depending on its form and purity, but it generally maintains this solid, crystalline nature.

Comment on solubility

Solubility of 2-fluoro-N-(4-fluorophenyl)-N-(2-hydroxyethyl)acetamide

The solubility of 2-fluoro-N-(4-fluorophenyl)-N-(2-hydroxyethyl)acetamide, represented by its chemical formula C2H4FNO, offers some interesting characteristics worth exploring.

Key factors influencing its solubility include:

  • Polarity: The presence of polar functional groups, such as the hydroxyethyl moiety, enhances its ability to interact with polar solvents, particularly water.
  • Fluorine Atoms: The fluorine atoms in the structure can influence the solubility by increasing the compound's lipophilicity, potentially affecting its solubility in organic solvents.
  • Hydrogen Bonding: The hydroxyl group enables hydrogen bonding, which can increase solubility in polar aprotic solvents.

As a result, 2-fluoro-N-(4-fluorophenyl)-N-(2-hydroxyethyl)acetamide is likely to exhibit:

  • Moderate solubility in water due to its polar characteristics.
  • Enhanced solubility in organic solvents, particularly those that can engage in dipole-dipole interactions.

In summary, while 2-fluoro-N-(4-fluorophenyl)-N-(2-hydroxyethyl)acetamide may not be highly soluble in all solvent systems, it demonstrates notable solubility behavior that can be anticipated based on its molecular structure and functional groups.

Interesting facts

Exploring 2-Fluoro-N-(4-fluorophenyl)-N-(2-hydroxyethyl)acetamide

2-Fluoro-N-(4-fluorophenyl)-N-(2-hydroxyethyl)acetamide is a fascinating compound with multiple applications in the fields of medicinal chemistry and material science. Here are some interesting facts about this compound:

  • Structural Significance: The presence of fluorine atoms in this compound enhances its biological activity and helps optimize pharmacological properties, making it a subject of interest in drug design.
  • Hydrogen Bonding: The hydroxyl group (-OH) provides an opportunity for hydrogen bonding, which can significantly affect the solubility and interaction with biological targets.
  • Pharmacological Potential: Compounds with acetamide functional groups often exhibit analgesic or anti-inflammatory properties, suggesting potential therapeutic applications.
  • Fluorinated Compounds: The incorporation of fluorine can increase lipophilicity, potentially improving the passage of the compound through cellular membranes, which is critical in drug development.
  • Electronics and Nanotechnology: Beyond its medicinal implications, this compound's distinct electronic properties may lend itself to applications in materials science, particularly in developing new materials with tailored functionalities.

In summary, 2-fluoro-N-(4-fluorophenyl)-N-(2-hydroxyethyl)acetamide is not just another compound; it serves as a reminder of how intricate molecular modifications can lead to significant advances in various scientific fields. As the well-known chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas." This sentiment encapsulates the excitement surrounding the exploration of compounds like this one.

Synonyms
10016-07-6
2,4'-Difluoro-N-(2-hydroxyethyl)acetanilide
BRN 2124077
ACETANILIDE, 2,4'-DIFLUORO-N-(2-HYDROXYETHYL)-
DTXSID10142985
DTXCID6065476
2-fluoro-N-(4-fluorophenyl)-N-(2-hydroxyethyl)acetamide
2,4/'-Difluoro-N-(2-hydroxyethyl)acetanilide