2-fluoro-N-(4-phenylphenyl)acetamide

Identification

Molecular formula

C₁₄H₁₂FNO

CAS number

219541-66-9

IUPAC name

2-fluoro-N-(4-phenylphenyl)acetamide

State

At room temperature, 2-fluoro-N-(4-phenylphenyl)acetamide is typically found in a solid state, specifically as a crystalline powder.

Melting point (Celsius)

102.00

Melting point (Kelvin)

375.15

Boiling point (Celsius)

332.00

Boiling point (Kelvin)

605.15

General information

Molecular weight

229.24g/mol

Molar mass

229.2410g/mol

Density

1.1968g/cm³

Appearence

2-Fluoro-N-(4-phenylphenyl)acetamide typically appears as a white to off-white crystalline powder. Its solid form makes it possible to handle it in powder or crystalline form. The appearance can vary slightly depending on the purity of the compound.

Comment on solubility

Solubility of 2-fluoro-N-(4-phenylphenyl)acetamide

The solubility of 2-fluoro-N-(4-phenylphenyl)acetamide can be influenced by several factors, particularly its molecular structure and interactions with solvents. Generally, the presence of the fluoro group can enhance its solubility in polar solvents due to its electronegative nature, while the aryl groups may limit solubility in non-polar solvents. Here are some key aspects to consider:

Polar Solvents: This compound may show better solubility in polar solvents such as water, methanol, or ethanol due to its ability to engage in hydrogen bonding and dipole interactions.
Non-Polar Solvents: In contrast, solubility in non-polar solvents like hexane may be limited due to the steric hindrance and lack of compatible interactions.
Temperature Effects: Increasing temperature can often enhance the solubility of organic compounds, and thus, 2-fluoro-N-(4-phenylphenyl)acetamide may demonstrate increased solubility at higher temperatures.

Ultimately, the solubility of this compound is a balance between its polar and non-polar characteristics. Understanding these interactions is crucial for applications in various chemical processes, formulations, or syntheses.

Interesting facts

Interesting Facts About 2-Fluoro-N-(4-phenylphenyl)acetamide

2-Fluoro-N-(4-phenylphenyl)acetamide is a compound that has garnered attention in both academic and industrial chemistry due to its unique properties and potential applications. Here are some key points of interest:

Structural Features: The presence of a fluorine atom within the acetamide structure facilitates enhanced electronic properties, making it a useful candidate for various chemical reactions and interactions.
Biological Relevance: Compounds containing both acetamide and fluorine functionalities, like 2-fluoro-N-(4-phenylphenyl)acetamide, are often explored for their pharmaceutical potentials. They may exhibit interesting activities as anti-inflammatory or analgesic agents.
Potential in Material Science: The unique electronic characteristics imparted by the fluorine atom can lead to the discovery of new materials with valuable properties, such as improved thermal stability or enhanced mechanical strength.
Synthesis Challenges: The synthesis of this compound can be intricate due to the need to maintain the stability of the phenyl groups while introducing the fluorine atom. This aspect encourages innovative synthetic strategies and a deeper understanding of organic synthesis techniques.
Interdisciplinary Applications: Beyond organic chemistry, this compound may find relevance in fields such as medicinal chemistry, materials science, and organic electronics, showcasing the interdisciplinary nature of modern scientific research.

In conclusion, 2-fluoro-N-(4-phenylphenyl)acetamide exemplifies how seemingly simple compounds can possess a wealth of complexity and potential. The exploration of its properties and applications reflects the dynamic nature of chemical research and the pathways toward innovation in various fields.

Synonyms

Acetanilide, alpha-fluoro-p-phenyl-

BRN 3054412

450-55-5

ACETANILIDE, 2-FLUORO-4'-PHENYL-

4-12-00-03249 (Beilstein Handbook Reference)

DTXSID90963317

N-([1,1'-Biphenyl]-4-yl)-2-fluoroacetamide