Skip to main content

2-Fluoro-N-isobutylacetamide

ADVERTISEMENT
Identification
Molecular formula
C6H12FNO
CAS number
32814-09-8
IUPAC name
2-fluoro-N-isobutyl-acetamide
State
State

At room temperature, 2-Fluoro-N-isobutylacetamide is in a liquid state.

Melting point (Celsius)
-32.00
Melting point (Kelvin)
241.15
Boiling point (Celsius)
213.00
Boiling point (Kelvin)
486.15
General information
Molecular weight
147.17g/mol
Molar mass
147.1730g/mol
Density
0.9732g/cm3
Appearence

2-Fluoro-N-isobutylacetamide is typically a colorless to pale yellow liquid. It is clear and free-flowing, with a characteristic odor related to its amide and fluoro substituents.

Comment on solubility

Solubility of 2-fluoro-N-isobutyl-acetamide

When considering the solubility of 2-fluoro-N-isobutyl-acetamide, several factors play a crucial role:

  • Polarity: The presence of the polar -NH and -CO functional groups contributes to the compound's ability to interact with polar solvents.
  • Hydrogen Bonding: The amide structure enables hydrogen bonding interactions with water, which can enhance its solubility in organic solvents that can also form hydrogen bonds.
  • Alkyl Substituent: The isobutyl group provides a hydrophobic character, which may limit the solubility in highly polar solvents but potentially increase compatibility with non-polar solvents.
  • Temperature Effects: As with many compounds, solubility may vary with temperature; generally, higher temperatures can increase solubility in solvents.

In summary, while 2-fluoro-N-isobutyl-acetamide shows a favorable solubility profile in polar solvents due to its functional groups, its overall solubility can be affected by the balance between its hydrophobic and hydrophilic characteristics. Thus, the context of its use and environmental conditions will determine its actual solubility behavior.

Interesting facts

Interesting Facts about 2-Fluoro-N-isobutyl-acetamide

2-Fluoro-N-isobutyl-acetamide is a fascinating compound that has garnered interest in various fields of research due to its unique properties and potential applications. Here are some noteworthy points about this chemical compound:

  • Fluorine Influence: The presence of the fluorine atom in the structure significantly alters the chemical behavior and reactivity of the compound. Fluorine is renowned for enhancing lipophilicity, which can influence biological activity.
  • Synthetic Applications: This compound serves as an important intermediate in organic synthesis. It can be utilized to create larger, more complex molecules, making it valuable in pharmaceuticals and materials science.
  • Biological Relevance: Compounds featuring fluorine are often more biologically active than their non-fluorinated counterparts. Studies suggest that 2-fluoro-N-isobutyl-acetamide may exhibit interesting interactions with biological systems, potentially enhancing its efficacy in medicinal applications.
  • Regulatory Aspects: As with many fluorinated compounds, there might be regulations surrounding the use and disposal of 2-fluoro-N-isobutyl-acetamide in certain jurisdictions due to environmental concerns associated with fluorinated substances.
  • Future Research: The ongoing investigation into the properties and functionalities of this compound opens new avenues for research in fields like drug design, agrochemicals, and advanced materials.

As a chemistry student or a researcher, understanding the nuances of such compounds can unlock numerous possibilities in both academic and industrial settings. The combination of fluorine and amide functionalities is a promising area of study with the potential to yield innovative solutions in chemistry and beyond!

Synonyms
N-Isobutylfluoroacetamide
371-44-8
2-Fluoro-N-isobutylacetamide
ACETAMIDE, 2-FLUORO-N-ISOBUTYL-
BRN 1748989
Acetamide, 2-fluoro-N-(2-methylpropyl)-
DTXSID80190594
4-04-00-00633 (Beilstein Handbook Reference)
SCHEMBL19559001
DTXCID20113085
AKOS006278701