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2-Fluoro-N-methyl-N-(1-naphthylmethyl)ethanamine

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Identification
Molecular formula
C14H16FN
CAS number
101987-86-4
IUPAC name
2-fluoro-N-methyl-N-(1-naphthylmethyl)ethanamine
State
State

The compound is typically a liquid at room temperature, noted for its clear or slightly yellow hue, which may vary based on its purity and environmental conditions.

Melting point (Celsius)
71.50
Melting point (Kelvin)
344.60
Boiling point (Celsius)
273.50
Boiling point (Kelvin)
546.60
General information
Molecular weight
201.27g/mol
Molar mass
201.2670g/mol
Density
1.1655g/cm3
Appearence

2-Fluoro-N-methyl-N-(1-naphthylmethyl)ethanamine typically appears as a liquid. It is often colorless or pale yellow, depending on the purity and specific conditions.

Comment on solubility

Solubility of 2-fluoro-N-methyl-N-(1-naphthylmethyl)ethanamine

Understanding the solubility of 2-fluoro-N-methyl-N-(1-naphthylmethyl)ethanamine is essential for its application in various chemical processes and formulations. This compound, due to its complex structure, exhibits unique solubility characteristics:

  • Polar and Non-Polar Interactions: The presence of both polar (amine and fluoro) and non-polar (naphthyl) groups suggests that the compound may have varying solubility in different solvents.
  • Solvent Compatibility: It is likely to be soluble in organic solvents such as ethanol, methanol, and acetone, while displaying limited solubility in water due to the hydrophobic naphthyl moiety.
  • pH Dependence: The solubility can be influenced by the pH of the solution, as amine groups can become protonated in acidic conditions, affecting solubility.
  • Structure-Activity Relationship: Understanding how different structural components impact solubility is key in pharmaceuticals, as it can affect bioavailability and therapeutic action.

It is often said that “like dissolves like.” Therefore, the interplay between polarity and hydrophobic characteristics plays a significant role in determining the solubility of this compound in various environments.

Interesting facts

Interesting Facts about 2-fluoro-N-methyl-N-(1-naphthylmethyl)ethanamine

2-fluoro-N-methyl-N-(1-naphthylmethyl)ethanamine is a fascinating compound that sits at the intersection of chemistry and pharmacology. Here are some neat insights:

  • Chemical Structure: This compound includes a fluorine atom attached to a carbon chain, which often enhances its reactivity and biological activity. The presence of the naphthyl group greatly contributes to its aromatic properties, making it more lipophilic.
  • Biological Significance: Compounds similar to 2-fluoro-N-methyl-N-(1-naphthylmethyl)ethanamine have been investigated for their potential therapeutic effects, particularly in relation to neurochemistry and drug design. Such structures can influence neurotransmitter activity, making them of great interest in developing medicines for psychiatric disorders.
  • Fluorinated Compounds: The substitution of hydrogen with a fluorine atom often alters the physical and chemical properties of organic molecules. This modification can influence the compound's affinity for biological targets, which is why fluorinated versions of other amines are pivotal in the pharmaceutical industry.
  • Synthetic Routes: The synthesis of this compound involves several chemical reactions, including potentially using catalytic methods to introduce the fluorine atom. This process exemplifies the creativity and precision needed in modern organic synthesis.
  • Applications in Research: As researchers explore its capabilities, 2-fluoro-N-methyl-N-(1-naphthylmethyl)ethanamine may serve as a useful tool in studying the action mechanisms of drugs, enabling a deeper understanding of how modifications at the molecular level can lead to significant pharmacological changes.

This compound reflects the incredible possibilities of organic chemistry and its ongoing contributions to science and medicine. As we explore more about compounds like 2-fluoro-N-methyl-N-(1-naphthylmethyl)ethanamine, we pave the way for innovative treatments and solutions in modern healthcare.

Synonyms
BRN 3269710
318-88-7
1-NAPHTHALENEMETHYLAMINE, N-(2-FLUOROETHYL)-N-METHYL-
N-(2-Fluoroethyl)-N-methylnaphthalene-1-methylamine
DTXSID20185666
4-12-00-03192 (Beilstein Handbook Reference)
DTXCID60108157