Skip to main content

2-Fluoro-N-methyl-N-(4-nitrophenyl)acetamide

ADVERTISEMENT
Identification
Molecular formula
C9H9FN2O3
CAS number
531840-30-1
IUPAC name
2-fluoro-N-methyl-N-(4-nitrophenyl)acetamide
State
State

At room temperature, 2-Fluoro-N-methyl-N-(4-nitrophenyl)acetamide exists as a solid. The compound possesses a crystalline structure which is typical for many organic compounds containing aromatic rings and nitro groups.

Melting point (Celsius)
118.50
Melting point (Kelvin)
391.65
Boiling point (Celsius)
251.80
Boiling point (Kelvin)
524.95
General information
Molecular weight
212.19g/mol
Molar mass
212.1850g/mol
Density
1.4140g/cm3
Appearence

2-Fluoro-N-methyl-N-(4-nitrophenyl)acetamide is typically found as a crystalline solid. The compound is characterized by its yellow color, which is common in nitro compounds due to the chromophore formed by the nitro group.

Comment on solubility

Solubility of 2-fluoro-N-methyl-N-(4-nitrophenyl)acetamide

2-fluoro-N-methyl-N-(4-nitrophenyl)acetamide, with the chemical formula C9H9FN2O3, exhibits interesting solubility characteristics that are important for its applications in various chemical contexts.

The solubility of this compound can typically be assessed in the following way:

  • Solvent Compatibility: This compound is likely to show greater solubility in polar solvents, such as water and alcohols, due to the presence of polar functional groups.
  • Influence of Functional Groups: The nitro group (-NO2) and the fluorine atom (F) introduce polarity, which often enhances solubility in polar environments.
  • Temperature Factors: Like many organic compounds, the solubility may increase with temperature, allowing for more effective dissolution in solution.
  • Crystallization and Purity: When considering the purity of samples, solubility tests can be critical in determining the quality and effectiveness of the compound in reactions.

As a general observation, it's important to conduct specific solubility tests for precise applications. In some cases, the phrase “the more the polar groups, the better the solubility in polar solvents” holds true. However, empirical data should always be reviewed to verify the actual behavior of 2-fluoro-N-methyl-N-(4-nitrophenyl)acetamide in a range of solvents and conditions.

Interesting facts

Interesting Facts about 2-Fluoro-N-methyl-N-(4-nitrophenyl)acetamide

2-Fluoro-N-methyl-N-(4-nitrophenyl)acetamide is a compound that showcases a fascinating interplay of molecular characteristics and potential applications. Here are some noteworthy points about this compound:

  • Fluorine Influence: The presence of a fluorine atom often enhances the biological activity and metabolic stability of organic compounds. In pharmaceutical chemistry, fluorine atoms can significantly alter the lipophilicity and chemical reactivity of molecules.
  • Structural Insights: This compound features a unique combination of a nitrophenyl group and an acetamide moiety. The aromatic nature of the nitrophenyl portion contributes to its overall electronic properties, making it an interesting subject for medicinal chemistry investigations.
  • Potential Applications: Compounds like 2-fluoro-N-methyl-N-(4-nitrophenyl)acetamide are often explored for various applications, including their use as intermediates in drug synthesis or as agrochemical agents. The nitro group is particularly interesting, as it can participate in various reduction reactions, leading to bioactive compounds.
  • Research Relevance: This compound may warrant further research due to its structural components. Investigating how the combination of the nitrophenyl and acetamide varies in different settings can yield important insights into structure-activity relationships (SAR) in drug design.
  • Analytical Techniques: Studying 2-fluoro-N-methyl-N-(4-nitrophenyl)acetamide often involves sophisticated methods such as NMR spectroscopy, mass spectrometry, and X-ray crystallography. These techniques help elucidate its structure and interactions at the molecular level.

As a conclusion, 2-fluoro-N-methyl-N-(4-nitrophenyl)acetamide stands out not only due to its unique molecular features but also because of its potential applications in various fields, especially in medicinal chemistry. The exploration of such compounds continues to captivate scientists looking to expand our understanding of chemical interactions and their implications in real-world applications.

Synonyms
10016-09-8
2-Fluoro-N-methyl-4'-nitroacetanilide
BRN 2127703
ACETANILIDE, 2-FLUORO-N-METHYL-4'-NITRO-
DTXSID30142987
DTXCID6065478
2-fluoro-N-methyl-N-(4-nitrophenyl)acetamide
2-Fluoro-N-methyl-4/'-nitroacetanilide
SCHEMBL28799029