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2-Fluoro-N-methyl-N-(3-methylphenyl)acetamide

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Identification
Molecular formula
C10H12FNO
CAS number
7735-58-9
IUPAC name
2-fluoro-N-methyl-N-(m-tolyl)acetamide
State
State

At room temperature, 2-Fluoro-N-methyl-N-(3-methylphenyl)acetamide is typically found in a solid state.

Melting point (Celsius)
81.00
Melting point (Kelvin)
354.20
Boiling point (Celsius)
305.50
Boiling point (Kelvin)
578.70
General information
Molecular weight
181.20g/mol
Molar mass
181.1990g/mol
Density
1.1300g/cm3
Appearence

2-Fluoro-N-methyl-N-(3-methylphenyl)acetamide typically appears as a solid. The exact color and texture can vary depending on the level of purity and form in which it is obtained.

Comment on solubility

Solubility of 2-fluoro-N-methyl-N-(m-tolyl)acetamide

The solubility of 2-fluoro-N-methyl-N-(m-tolyl)acetamide (C10H12FNO) is influenced by its chemical structure and the presence of functional groups. This compound exhibits certain characteristics that provide insights into its solubility behaviors:

  • Polarity: The presence of the fluorine atom and the amide group contributes to the polarity of the molecule, which often enhances its solubility in polar solvents.
  • Hydrogen Bonding: The amide functional group allows the compound to participate in hydrogen bonding, potentially increasing its solubility in water.
  • Aromatic Character: The m-tolyl (methyl toluene) group introduces a hydrophobic character that can limit solubility in more aqueous environments.

Overall, while 2-fluoro-N-methyl-N-(m-tolyl)acetamide is likely to be soluble in polar organic solvents such as methanol or ethanol, its intricate balance of hydrophobic and hydrophilic interactions suggests varying degrees of solubility in water and non-polar solvents. As noted, "the solubility of a compound is a reflection of its structural intricacies and interactions in a given medium."

In summary, when exploring how 2-fluoro-N-methyl-N-(m-tolyl)acetamide behaves in different solvents, consider the factors above to better understand its solubility properties.

Interesting facts

Interesting Facts About 2-Fluoro-N-methyl-N-(m-tolyl)acetamide

2-Fluoro-N-methyl-N-(m-tolyl)acetamide is a compound that has garnered interest in various fields of chemistry, particularly in medicinal chemistry and synthetic organic chemistry. Here are some fascinating aspects of this compound:

  • Unique Structure: The presence of a fluorine atom in its structure contributes to unique chemical properties such as enhanced lipophilicity and improved metabolic stability.
  • Pharmaceutical Potential: This compound is often explored as a potential drug candidate due to its ability to interact with biological targets in a selective manner. Scientists have noted that fluorinated compounds can exhibit significant differences in activity compared to their non-fluorinated counterparts.
  • Diverse Applications: Beyond pharmaceuticals, 2-fluoro-N-methyl-N-(m-tolyl)acetamide finds applications in materials science and agrochemicals, showcasing its versatility in different fields.
  • Mechanistic Studies: Researchers are interested in the mechanisms through which this compound exerts its effects, leading to insights on how similar structures can be optimized for greater potency and selectivity.
  • Synergistic Effects: The combination of fluorine with the aromatic m-tolyl group may lead to synergistic effects, enhancing the compound's overall biological activity.

In summary, 2-fluoro-N-methyl-N-(m-tolyl)acetamide exemplifies the importance of fluorinated compounds in contemporary chemistry. With its intriguing structural attributes and potential applications, it remains a subject of ongoing research and excitement!

Synonyms
10016-01-0
m-ACETOTOLUIDIDE, 2-FLUORO-N-METHYL-
BRN 2096783
2-Fluoro-N-methyl-m-acetotoluidide
DTXSID70142981
DTXCID6065472
2-fluoro-N-methyl-N-(3-methylphenyl)acetamide
2-fluoro-N-methyl-N-(m-tolyl)acetamide
2-Fluoro-N-methyl-N-m-tolylacetamide
starbld0028171
AKOS040752903