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Fluoroacetamide

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Identification
Molecular formula
C2H4FNO
CAS number
640-19-7
IUPAC name
2-fluoroacetamide
State
State

Fluoroacetamide is solid at room temperature, maintaining a stable structure unless dissolved in water or heated. It is often handled in its solid state for industrial and laboratory purposes.

Melting point (Celsius)
106.00
Melting point (Kelvin)
379.15
Boiling point (Celsius)
188.00
Boiling point (Kelvin)
461.15
General information
Molecular weight
77.06g/mol
Molar mass
77.0580g/mol
Density
1.2340g/cm3
Appearence

Fluoroacetamide is a colorless, crystalline solid. It tends to form needles or flaky crystals and is typically odorless.

Comment on solubility

Solubility of 2-Fluoroacetamide

2-Fluoroacetamide, with the formula C2H4FNO, exhibits notable solubility characteristics that are worth exploring. This compound is known to be soluble in various polar solvents, making it an interesting candidate for chemical applications. Here are some key points regarding its solubility:

  • Water Solubility: 2-Fluoroacetamide is soluble in water due to its ability to form hydrogen bonds with water molecules, which is a crucial aspect of its chemical nature.
  • Solvent Interactions: It shows good solubility in common polar aprotic solvents like dimethyl sulfoxide (DMSO) and acetonitrile, which can enhance its reactivity in certain chemical reactions.
  • Alkane Solubility: On the flip side, 2-fluoroacetamide is poorly soluble in nonpolar solvents such as hexane, which underscores the importance of polarity in determining solubility.

In summary, the solubility of 2-fluoroacetamide is greatly influenced by the nature of the solvent and its polarity. As a polar compound, it interacts favorably with polar solvents, allowing for its utilization in various synthesis and reaction environments. Understanding its solubility will facilitate better application choices in chemical processes.

Interesting facts

Interesting Facts About 2-Fluoroacetamide

2-Fluoroacetamide is a fascinating compound that has garnered attention for its unique chemical properties and potential applications in various fields. Here are some interesting facts about this intriguing compound:

  • Fluorinated Functional Group: The presence of a fluorine atom in the acetamide structure significantly alters its reactivity and biological activity. Fluorination is known to enhance pharmacological properties, making compounds more potent and selectively active.
  • Role in Synthesis: 2-Fluoroacetamide can be utilized as an important building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its reactivity allows chemists to create a wide range of derivatives with desirable traits.
  • Biological Activity: This compound may exhibit interesting biological properties. Some studies have indicated that fluorinated compounds can influence physiological processes, making them valuable in drug development for various diseases.
  • Analytical Applications: Due to its distinctive nitrogen and fluorine atoms, 2-fluoroacetamide can serve as a useful reagent in analytical chemistry. It can assist in identifying compounds through techniques such as NMR (Nuclear Magnetic Resonance) spectroscopy.
  • Research Potential: Ongoing research in the field of material science explores the potential of 2-fluoroacetamide in creating novel materials. Its unique properties may contribute to advances in the development of polymers and other high-performance materials.

Overall, 2-fluoroacetamide stands out in the realm of chemical compounds, offering multiple avenues for exploration and innovation. As research progresses, it may hold even more surprises in store!

Synonyms
FLUOROACETAMIDE
2-Fluoroacetamide
Monofluoroacetamide
Acetamide, 2-fluoro-
Baran
Flutritex 1
Caswell No. 461
2-Fluoro-Acetamide
Fluoroacetamide [BSI:ISO]
CHEBI:53124
HSDB 2880
RCRA waste no. P057
EINECS 211-363-1
NSC 31876
EPA Pesticide Chemical Code 075002
BRN 1739054
DTXSID2034255
UNII-B18R611M38
AI3-25667
NSC-31876
WLN: ZV1F
B18R611M38
FLUOROACETAMIDE [MI]
FLUOROACETAMIDE [ISO]
FLUOROACETAMIDE [HSDB]
DTXCID0014255
Sjyhcahiktp
2Fluoroacetamide
Acetamide, 2fluoro
alpha-fluoroacetamide
Pesticide Code: 075002
4-02-00-00454 (beilstein handbook reference)
fvtwjxmfyoxokk-uhfffaoysa-n
rodex
un2811
640-19-7
Fluorkill
Fluoroacetic acid amide
Megatox
Fussol
Yanock
Fluoroakil 100
Fluorakil 100
Navron
Compound 1081
Fluoracetamide
AFL 1081
RCRA waste number P057
Amid kyseliny fluoroctove
Amid kyseliny fluoroctove [Czech]
FTM
2-fluoranylethanamide
CHEMBL160811
NSC31876
Tox21_301297
BDBM50226191
AKOS009031511
NCGC00166013-01
NCGC00257537-01
CAS-640-19-7
Fluoroacetamide 100 microg/mL in Ethanol
DB-029786
DB-050525
F0029
NS00006286
EN300-19853
A10407
C18675
A834612
Q419124
Z104475768