Skip to main content

2-Fluoroacetyl fluoride

ADVERTISEMENT
Identification
Molecular formula
C2H2FO2
CAS number
359-05-7
IUPAC name
2-fluoroacetyl fluoride
State
State

At room temperature, 2-fluoroacetyl fluoride is a liquid.

Melting point (Celsius)
-121.00
Melting point (Kelvin)
152.15
Boiling point (Celsius)
38.00
Boiling point (Kelvin)
311.15
General information
Molecular weight
94.04g/mol
Molar mass
94.0350g/mol
Density
1.2334g/cm3
Appearence

2-Fluoroacetyl fluoride is a colorless liquid with a pungent odor.

Comment on solubility

Solubility of 2-Fluoroacetyl Fluoride

2-Fluoroacetyl fluoride, with the chemical formula C2H2F3O, exhibits interesting solubility characteristics that are important for its applications and handling. In terms of solubility in various solvents, here are some key points to consider:

  • Polar Solvents: 2-Fluoroacetyl fluoride is generally soluble in polar organic solvents such as acetone and dimethyl sulfoxide (DMSO), which facilitate interactions via dipole-dipole forces.
  • Non-Polar Solvents: When it comes to non-polar solvents like hexane, the solubility is significantly lower due to the lack of favorable interactions.
  • Water Solubility: The compound has low to moderate solubility in water, attributed to its molecular structure and the presence of functional groups that can engage in limited hydrogen bonding.
  • Hydrolytic Stability: It is also important to note that 2-fluoroacetyl fluoride is susceptible to hydrolysis, which occurs when it comes into contact with water, leading to the formation of additional compounds and further influencing overall solubility.

In practice, the solubility can vary significantly depending on temperature and the presence of other solutes in a solution. Understanding the solubility profile of 2-fluoroacetyl fluoride is essential in various chemical processes, whether it be in a laboratory setting or an industrial application.

Interesting facts

Interesting Facts about 2-Fluoroacetyl Fluoride

2-Fluoroacetyl fluoride is an intriguing compound that garners attention in both industrial and research settings. Below are some captivating aspects of this unique chemical:

  • Organofluorine Chemistry: This compound belongs to a class known as organofluorines, which are characterized by the presence of carbon-fluorine bonds. These bonds are known for their strength and stability, making organofluorines vital in pharmaceuticals and agrochemicals.
  • Application in Synthesis: 2-Fluoroacetyl fluoride is often utilized as an intermediate in the synthesis of various organic compounds. Its reactivity allows scientists to develop new molecules with significant pharmaceutical applications.
  • Toxicological Considerations: As with many organofluorine compounds, caution is advised in handling 2-fluoroacetyl fluoride due to its potential toxicity and reactivity. Proper safety measures and protocols are essential to ensure safe laboratory practices.
  • Fluorine's Unique Properties: The presence of fluorine in this compound imparts unique chemical properties, including enhanced metabolic stability and lipophilicity. Such traits are often sought after in drug development, providing better bioavailability and longer-lasting effects.
  • Research Significance: The study of 2-fluoroacetyl fluoride and related compounds contributes to advances in medicinal chemistry. Exploring its reactions and properties can lead to the discovery of new chemical pathways and innovative therapeutic agents.

In conclusion, the study of 2-fluoroacetyl fluoride not only deepens our understanding of organofluorine chemistry but also highlights its practical significance in the field of synthetic organic chemistry. As researchers continue to explore its applications, this compound remains an important subject of study in the quest for novel chemical solutions.

Synonyms
Fluoroacetyl fluoride
1514-42-7
2-fluoroacetyl fluoride
ACETYL FLUORIDE, FLUORO-
Fluorid kyseliny fluoroctove
Fluorid kyseliny fluoroctove [Czech]
TL 736
BRN 1739050
LPGXUEOAYSYXNJ-UHFFFAOYSA-
DTXSID70164784
MFCD01673458
AKOS006279564
InChI=1/C2H2F2O/c3-1-2(4)5/h1H2