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2-fluoroethyl 2-(4-phenylphenyl)acetate

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Identification
Molecular formula
C16H15FO2
CAS number
7149-39-5
IUPAC name
2-fluoroethyl 2-(4-phenylphenyl)acetate
State
State

State at Room Temperature: The compound is typically in a liquid state at room temperature, primarily due to its relatively low melting point and characteristic ester functionalities.

Melting point (Celsius)
-48.00
Melting point (Kelvin)
225.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
242.27g/mol
Molar mass
242.2670g/mol
Density
1.0805g/cm3
Appearence

The compound appears as a colorless liquid, often with a characteristic ester-like odor. It may vary in viscosity but typically remains a free-flowing liquid.

Comment on solubility

Solubility of 2-fluoroethyl 2-(4-phenylphenyl)acetate

The solubility of 2-fluoroethyl 2-(4-phenylphenyl)acetate in various solvents is an intriguing subject, as it provides insight into its chemical behavior and potential applications. Understanding its solubility can help predict how it interacts with other substances and influences its behavior in different environments.

Factors Affecting Solubility

When analyzing the solubility of this compound, consider the following factors:

  • Polarity: The presence of both the fluorine atom and the ester functional group in the structure contributes to its polarity, which significantly affects solubility.
  • Hydrogen Bonding: The ability to form hydrogen bonds can enhance solubility in polar solvents.
  • Temperature: Increasing temperature generally increases solubility for solids and some liquids, but specific behaviors may vary.
  • Solvent Type: It is crucial to identify whether the compound is more soluble in polar or non-polar solvents, as this will influence its practical applications.

Solubility Behavior

In practice, it is observed that:

  • Low solubility in water, due to its relatively non-polar characteristics.
  • Higher solubility in organic solvents such as ethanol or acetone, where it can better interact due to its ester functional group.

Overall, *2-fluoroethyl 2-(4-phenylphenyl)acetate* demonstrates a complex solubility profile, significantly influenced by its chemical structure and the nature of the solvent used. Understanding these properties is vital for any applications in synthesis or formulation processes.

Interesting facts

Interesting Facts about 2-fluoroethyl 2-(4-phenylphenyl)acetate

2-fluoroethyl 2-(4-phenylphenyl)acetate is a fascinating compound that showcases the intricacies of organic synthesis and functional group manipulation. Here are some noteworthy points regarding this compound:

  • Fluorinated Compounds: The presence of a fluorine atom in the ethyl group makes this compound particularly interesting. Fluorine is known for its ability to enhance biological activity and pharmacological properties, often leading to increased potency in medicinal applications.
  • Versatile Intermediate: This compound can serve as an important intermediate in organic synthesis. It can be utilized in the preparation of various materials, including pharmaceuticals and agrochemicals, thanks to its reactivity derived from the functional groups present.
  • Role of Phenyl Groups: The 4-phenylphenyl substituent contributes significant electronic and steric effects, influencing the compound's behavior in chemical reactions. This arrangement can also affect its solubility, stability, and overall molecular interactions.
  • Applications in Stereochemistry: The compound’s asymmetric centers may lead to interesting stereochemical outcomes, which can be critical in developing compounds with specific chiral properties essential for biological activity.
  • Research and Development: Ongoing studies in organic chemistry continuously explore the potential applications of compounds like 2-fluoroethyl 2-(4-phenylphenyl)acetate in drug discovery and design, whereby understanding its structure-activity relationship becomes paramount.

In summary, 2-fluoroethyl 2-(4-phenylphenyl)acetate is more than just a chemical entity; it represents the intersection of innovation and research in chemistry. Its unique structure offers insights into how modifications at the molecular level can lead to enhanced effects in various fields, especially in the realm of pharmaceuticals.

Synonyms
FLUENETIL
4301-50-2
Fluenethyl
Mytrol
Lambrol
Fluenetil [ISO]
Fluenthyl
Fluenyl
Labrol EC
Fluenethyl [France]
Caswell No. 462A
HSDB 6437
TH 367-1
4-Biphenylacetic acid, 2-fluoroethyl ester
2-Fluorethyl-4-biphenylacetat
EPA Pesticide Chemical Code 462200
UNII-S8K34P1L02
Acetic acid, 4-biphenylyl-, 2-fluoroethyl ester
BRN 2979711
2-Fluoroethyl-4-bifenylacetaat
2-Fluor-ethyl-4-biphenylacetat
2-Fluorethyl-4-biphenylacetat [Denmark]
2-Fluor-ethyl-4-biphenylacetat [German]
(1,1'-Biphenyl)-4-acetic acid, 2-fluoroethyl ester
AI3-27477
2-Fluoroethyl (1,1'-biphenyl)-4-acetate
4-Bifenilacetato de 2-fluoroetilo
S8K34P1L02
2-Fluoroethyl-4-bifenylacetaat [Netherlands]
4-Bifenilacetato de 2-fluoroetilo [Spanish]
FLUENETIL [HSDB]
2-Fluorethylester kyseliny xenyloctove [Czech]
M 2060
2-(4-Bifenil)aceto de 2-fluoroetil
2-(4-Bifenil)aceto de 2-fluoroetil [Portugese]
2-Fluorethylester kyseliny xenyloctove
2-(4-Bifenilil)-aceto di 2-fluoroetile [Italian]
2-(4-Biphenylyl)acetate de 2-fluoroethyle [French]
2-(4-Bifenilil)-aceto di 2-fluoroetile
Biphenylyl-4,2-acetate de (fluoro-2-ethyle) [French]
2-(4-Biphenylyl)acetate de 2-fluoroethyle
DTXSID9058103
Biphenylyl-4,2-acetate de (fluoro-2-ethyle)
Fluenethyl (France)
.BETA.-FLUOROETHYL 4-BIPHENYLACETATE
ETHANOL, 2-FLUORO-, 4-BIPHENYLACETATE
M-2060
[1,1'-Biphenyl]-4-acetic acid, 2-fluoroethyl ester
2-Fluorethyl-4-biphenylacetat (Denmark)
2-Fluor-ethyl-4-biphenylacetat (German)
4-Bifenilacetato de 2-fluoroetilo (Spanish)
2-Fluoroethyl-4-bifenylacetaat (Netherlands)
2-Fluorethylester kyseliny xenyloctove (Czech)
2-(4-Bifenil)aceto de 2-fluoroetil (Portugese)
2-(4-Bifenilil)-aceto di 2-fluoroetile (Italian)
Biphenylyl-4,2-acetate de (fluoro-2-ethyle) (French)
Caswell No 462A
DTXCID2031871
2-Fluoroethyl biphenyl-4-ylacetate
4-biphenylacetic acid 2-fluoroethyl ester
BETA-FLUOROETHYL 4-BIPHENYLACETATE
2-(4-Biphenylyl) acetate de 2-fluoroethyle
2-FLUOROETHYL 4-BIPHENYLACETATE(ACN)
2-(4-Biphenylyl) acetate de 2-fluoroethyle (French)
2-fluoroethyl 2-(4-phenylphenyl)acetate
M2060; TH 367-1
2-fluoroethyl 2-([1,1'-biphenyl]-4-yl)acetate
2-Fluoroethyl 4-biphenylacetate
SCHEMBL161595
CHEBI:82161
XAERLJMOUYEBAB-UHFFFAOYSA-N
EAA30150
AKOS040746834
C19031
Q5462651