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2-Fluoroethyl 2-aminoacetate

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Identification
Molecular formula
C4H8FNO2
CAS number
459-40-3
IUPAC name
2-fluoroethyl 2-aminoacetate
State
State

At room temperature, 2-Fluoroethyl 2-aminoacetate is in a liquid state.

Melting point (Celsius)
-31.00
Melting point (Kelvin)
242.15
Boiling point (Celsius)
187.00
Boiling point (Kelvin)
460.15
General information
Molecular weight
135.12g/mol
Molar mass
135.1200g/mol
Density
1.1960g/cm3
Appearence

2-Fluoroethyl 2-aminoacetate typically appears as a colorless to pale yellow liquid. It is a clear compound that may have a mild odor.

Comment on solubility

Solubility of 2-fluoroethyl 2-aminoacetate

The solubility of 2-fluoroethyl 2-aminoacetate can be assessed through several key factors that dictate its interaction with various solvents. Generally speaking, amines and their derivatives often display interesting solubility characteristics due to their polarity and ability to form hydrogen bonds.

Here are some important points to consider:

  • Polarity: The presence of the amino group (-NH2) contributes significantly to the polarity of 2-fluoroethyl 2-aminoacetate, potentially increasing its solubility in polar solvents like water.
  • Hydrogen Bonding: The amino group can participate in hydrogen bonding with solvent molecules, which can enhance solubility further.
  • Fluorine Influence: The presence of the fluorine atom may influence the compound's overall solubility due to its electronegative nature. This can lead to unique interactions within various solvent systems.
  • Hydrophobic vs. Hydrophilic Balance: The ethyl group contributes hydrophobic characteristics, which may reduce solubility in very polar solvents.

In summary, while 2-fluoroethyl 2-aminoacetate is likely to be soluble in polar solvents due to its amino group and the potential for hydrogen bonding, the solubility can vary depending on solvent conditions. Experimental verification in known solvents is crucial to accurately determine its solubility profile.

Interesting facts

Interesting Facts About 2-Fluoroethyl 2-Aminoacetate

2-Fluoroethyl 2-aminoacetate, a fascinating compound, plays a vital role in the field of medicinal chemistry and synthetic organic chemistry. Here are some intriguing aspects of this compound:

  • Functional Versatility: The presence of both fluoro and amino groups in the structure allows 2-fluoroethyl 2-aminoacetate to serve as an important building block in the synthesis of more complex molecules and pharmaceuticals.
  • Biological Significance: The fluorine atom in the compound often enhances biological activity and metabolic stability, making it an attractive candidate for drug discovery.
  • Research Applications: This compound may be utilized in studying enzyme activities, receptor interactions, and other biological processes due to its specific functional groups, making it a valuable tool in biochemical research.
  • Synthesis Pathways: Chemists have developed various synthesis pathways for 2-fluoroethyl 2-aminoacetate, showcasing its accessibility for laboratory procedures and industrial applications.
  • Influence on Properties: The introduction of fluorine can dramatically alter the physicochemical properties of the compound, including its lipophilicity and binding affinity, which can be crucial for designing effective therapeutics.

As one delves deeper into its potential applications and significance, it's clear that 2-fluoroethyl 2-aminoacetate provides a fascinating intersection of fundamental chemistry and practical application, contributing to advancements in both academic and industrial settings.

Synonyms
2-fluoroethyl glycinate
371-39-1