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2-Fluoroethyl 4-fluorobutanoate

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Identification
Molecular formula
C6H10F2O2
CAS number
62202-76-4
IUPAC name
2-fluoroethyl 4-fluorobutanoate
State
State

At room temperature, 2-fluoroethyl 4-fluorobutanoate exists as a liquid.

Melting point (Celsius)
-51.00
Melting point (Kelvin)
222.15
Boiling point (Celsius)
162.00
Boiling point (Kelvin)
435.15
General information
Molecular weight
164.15g/mol
Molar mass
164.1530g/mol
Density
1.1066g/cm3
Appearence

2-Fluoroethyl 4-fluorobutanoate is a colorless liquid.

Comment on solubility

Solubility of 2-fluoroethyl 4-fluorobutanoate

The solubility of 2-fluoroethyl 4-fluorobutanoate can be influenced by various factors such as temperature, the presence of solvents, and the molecular structure of the compound itself. In general:

  • Polarity: The presence of fluorine atoms contributes to the compound's overall polarity, which can enhance its solubility in polar solvents like water.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents (e.g., ethanol, acetone) compared to nonpolar solvents due to its moderate polarity.
  • Hydrogen Bonding: If hydrogen bonding is possible with the solvent molecules, it may further increase solubility.
  • Temperature Effects: Increased temperature typically promotes greater solubility, possibly facilitating the dissolution of 2-fluoroethyl 4-fluorobutanoate in suitable solvents.

In conclusion, while specific solubility data for 2-fluoroethyl 4-fluorobutanoate may not be widely documented, understanding the influence of its chemical structure on solubility can guide predictions on its behavior in various solvents. The remarkable versatility of solubility in chemical compounds often emphasizes the significance of molecular interactions.

Interesting facts

Interesting Facts about 2-Fluoroethyl 4-Fluorobutanoate

2-Fluoroethyl 4-fluorobutanoate is a fascinating chemical compound that showcases the unique versatility of fluorinated organic molecules. As a chemist or chemistry student, you'll find its properties and applications immensely interesting. Here are some highlights:

  • Fluorine's Role: The presence of fluorine in this compound significantly alters its physical and chemical properties compared to its non-fluorinated analogs. Fluorine is known for its electronegativity, which can enhance the compound's reactivity and affinity for binding with biological systems.
  • Synthesis Applications: 2-Fluoroethyl 4-fluorobutanoate can be utilized as a synthetic intermediate in the production of various pharmaceuticals, agrochemicals, and fluorinated materials. This contributes to the growing field of medicinal chemistry where fluorinated compounds often display improved efficacy and reduced side effects.
  • Biological Relevance: Compounds like 2-fluoroethyl 4-fluorobutanoate may be explored for their potential applications in drug design. Fluorine substituents often serve to increase metabolic stability while maintaining biological activity.
  • Environmental Considerations: The introduction of fluorine into organic compounds can also raise questions about their environmental impact. Researchers are increasingly focusing on the degradation pathways and accumulation of fluorinated compounds in ecosystems.
  • Structure-Activity Relationship Studies: This compound serves as an excellent model for studying structure-activity relationships in drug development, where minor modifications can lead to significant changes in biological activity.

In conclusion, 2-fluoroethyl 4-fluorobutanoate exemplifies the profound impact that fluorinated compounds have in various scientific domains, especially in pharmaceutical development. The study of such compounds not only deepens our understanding of chemical properties but also enhances our capability to innovate and create new therapeutic agents.

Synonyms
2-Fluoroethyl gamma-fluorobutyrate
371-29-9
TL 1127
BUTYRIC ACID, 4-FLUORO-, 2-FLUOROETHYL ESTER
beta-Fluoroethyl gamma-fluorobutyrate
BRN 1756085
DTXSID60190592
3-02-00-00621 (Beilstein Handbook Reference)
DTXCID00113083