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2-Fluoroethyl(trimethyl)ammonium

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Identification
Molecular formula
C5H12FN
CAS number
462-27-1
IUPAC name
2-fluoroethyl(trimethyl)ammonium
State
State

Under standard conditions of temperature and pressure, 2-Fluoroethyl(trimethyl)ammonium exists as a liquid.

Melting point (Celsius)
-10.00
Melting point (Kelvin)
263.15
Boiling point (Celsius)
147.00
Boiling point (Kelvin)
420.15
General information
Molecular weight
136.21g/mol
Molar mass
136.2060g/mol
Density
0.8998g/cm3
Appearence

2-Fluoroethyl(trimethyl)ammonium exhibits a clear, colorless liquid appearance. It tends to have physical properties similar to other liquid organic ammonium salts.

Comment on solubility

Solubility of 2-fluoroethyl(trimethyl)ammonium

The solubility of 2-fluoroethyl(trimethyl)ammonium, a quaternary ammonium compound, can vary based on several factors. Understanding its solubility is crucial for applications in various fields including pharmaceuticals and chemical synthesis. Here are some key points to consider:

  • Polar Nature: The presence of both the polar fluoroethyl group and the positively charged ammonium moiety contributes to enhanced solubility in polar solvents, particularly water.
  • Hydrogen Bonding: The positively charged nitrogen can engage in hydrogen bonding with water molecules, which generally improves solubility.
  • Organic Solvents: In addition to water, this compound may also dissolve well in organic solvents like ethanol and acetone, due to the balance between hydrophobic and hydrophilic characteristics.

However, the specific conditions such as temperature and the presence of other solutes can significantly influence the solubility behavior. Therefore, it is essential to conduct empirical testing to determine the exact solubility parameters for practical applications.

Interesting facts

Interesting Facts about 2-Fluoroethyl(trimethyl)ammonium

2-Fluoroethyl(trimethyl)ammonium is an intriguing quaternary ammonium compound that is notable for its applications in various fields of chemistry and biochemistry. Here are some compelling aspects of this compound:

  • Quaternary Ammonium Nature: As a quaternary ammonium salt, this compound features a positively charged nitrogen atom bonded to four groups, which enhances its reactivity and biological involvement.
  • Fluorinated Alkyl Group: The presence of a fluoroethyl group can profoundly influence the compound's properties, including its solubility and interaction with biological membranes. Fluorine atoms can enhance lipophilicity, making the compound more bioavailable in certain applications.
  • Applications in Synthesis: Compounds like 2-fluoroethyl(trimethyl)ammonium serve as versatile intermediates in synthetic organic chemistry. They can be used to synthesize various pharmaceutical agents and other organic compounds.
  • Biological Activity: Due to its ammonium ion and fluorinated structure, this compound may exhibit interesting biological effects, potentially acting as a pharmacophore in drug design and development.
  • Stability and Reactivity: The stability of quaternary ammonium compounds lends them a favorable profile for exploring chemical reactivity, while their reactivity with nucleophiles makes them useful in various synthetic pathways.

In summary, 2-fluoroethyl(trimethyl)ammonium is a compound that exemplifies the intersection of organic synthesis, drug development, and the unique behavior of fluorinated substances. The opportunities it presents for research and practical applications make it a fascinating subject of study in the field of chemistry.

Synonyms
44580-38-3
SCHEMBL15637581
DTXSID70274498