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glycidyl fluoride

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Identification
Molecular formula
C3H5FO
CAS number
503-18-8
IUPAC name
2-(fluoromethyl)oxirane
State
State

At room temperature, glycidyl fluoride is a liquid. It maintains its liquid form under standard atmospheric pressures and temperatures.

Melting point (Celsius)
-108.00
Melting point (Kelvin)
165.15
Boiling point (Celsius)
72.00
Boiling point (Kelvin)
345.15
General information
Molecular weight
76.07g/mol
Molar mass
76.0730g/mol
Density
1.1630g/cm3
Appearence

Glycidyl fluoride is a colorless liquid. It is typically clear and has no significant color, making it appear similar to water in its liquid state.

Comment on solubility

Solubility of 2-(fluoromethyl)oxirane

2-(fluoromethyl)oxirane, also known as fluoromethyloxirane, is a compound with intriguing solubility characteristics. Understanding its solubility can be essential for various chemical applications and reactions.

In terms of solubility:

  • Polar Solvents: 2-(fluoromethyl)oxirane displays good solubility in polar solvents due to its polar oxirane ring and the presence of a fluoromethyl group. This enhances its interactions with solvent molecules.
  • Nonpolar Solvents: Its solubility in nonpolar solvents is comparatively lower, making it less favorable for reactions that occur in nonpolar mediums.
  • Aqueous Solubility: The compound has limited solubility in water. This is primarily due to its hydrophobic properties resulting from the fluoromethyl group, which hinders extensive hydrogen bonding with water molecules.

Overall, the solubility of 2-(fluoromethyl)oxirane can be summarized as significantly influenced by the nature of the solvent:

  1. If the solvent is polar, expect enhanced solubility.
  2. For nonpolar solvents, anticipate reduced solubility.
  3. In aqueous environments, solubility is limited.

These characteristics make 2-(fluoromethyl)oxirane a versatile compound in organic synthesis, especially when selecting appropriate solvents for reactions. As is often said in chemistry, "like dissolves like," and this principle applies remarkably well to this compound.

Interesting facts

Interesting Facts about 2-(Fluoromethyl)oxirane

2-(Fluoromethyl)oxirane, commonly known as fluoromethyl epoxide, is an intriguing compound with several notable features:

  • Reactivity: As an epoxide, 2-(fluoromethyl)oxirane exhibits high reactivity due to the strained three-membered ring structure. This makes it an excellent target for nucleophilic attack, making it valuable in organic synthesis.
  • Fluorine's Influence: The fluoromethyl group can significantly enhance the compound's reactivity and stability compared to its non-fluorinated counterparts. The presence of fluorine often leads to altered electronic properties, which can be beneficial in various chemical reactions.
  • Application in Synthesis: This compound is valuable in the synthesis of more complex molecules. It can act as a building block in pharmaceuticals and agrochemicals, exemplifying its significance in medicinal chemistry.
  • Environmental Considerations: Due to the increasing importance of fluorinated compounds in various industries, understanding their environmental impact is crucial. Research is ongoing to evaluate the safety and sustainability of using such compounds.

As one researcher noted, “The incorporation of fluorinated groups can dramatically modify the properties of compounds, leading to exciting new applications in various fields.”
Understanding the nuances of compounds like 2-(fluoromethyl)oxirane can lead to breakthroughs in chemical synthesis and materials science.

In summary, 2-(fluoromethyl)oxirane is more than just a chemical compound; it represents a fascinating area of study where chemistry, biology, and environmental science intersect.

Synonyms
Epifluorohydrin
1,2-EPOXY-3-FLUOROPROPANE
Oxirane, (fluoromethyl)-
3-Fluoropropene-1,2-oxide
Propane, 1,2-epoxy-3-fluoro-
CCRIS 6034
BRN 0102460
0ZZ4ROH5IL
EINECS 207-960-1
NSC 21303
oxirane, 2-(fluoromethyl)-
FLUOROMETHYLOXIRANE
NSC-21303
NSC-88608
3-FLUOROPROPYLENE OXIDE
DTXSID4025244
5-17-01-00019 (Beilstein Handbook Reference)
J1.567I
1-fluoro-2,3-epoxypropane
DTXCID705244
Oxirane, (fluoromethyl)-(9CI)
3-FLUOROPROPENE 1,2-OXIDE
207-960-1
oxirane, (fluoromethyl)-, (+-)-
503-09-3
2-(Fluoromethyl)oxirane
(Fluoromethyl)oxirane
Epifluorhydrine
3-Fluoro-1,2-propenoxide
NSC21303
MFCD00005131
OXIRANE, (FLUOROMETHYL)-, (+/-)-
WLN: T3OTJ B1F
Propane,2-epoxy-3-fluoro-
UNII-0ZZ4ROH5IL
2-fluoromethyl-oxirane
Epifluorohydrin, 98%
2-(Fluoromethyl)oxirane #
ALBB-023708
NSC88608
BBL101624
GEO-01282
STL555420
AKOS005259611
AT22387
PS-10259
CS-0238445
NS00042658
EN300-195514
Q27251088