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(2-Fluorophenyl)urea

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Identification
Molecular formula
C7H7FN2O
CAS number
2285-49-2
IUPAC name
(2-fluorophenyl)urea
State
State

At room temperature, (2-Fluorophenyl)urea exists as a solid. It is important to handle the compound in a well-ventilated area as it may have mild aromatic odors.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.00
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.00
General information
Molecular weight
154.15g/mol
Molar mass
154.1460g/mol
Density
1.3920g/cm3
Appearence

(2-Fluorophenyl)urea usually appears as a white crystalline solid. The crystals can exhibit different shapes including needles and plates depending on the method of crystallization used. It is a fairly stable compound under standard temperature and pressure.

Comment on solubility

Solubility of (2-Fluorophenyl)urea

(2-Fluorophenyl)urea, also known by its systematic name, can exhibit notable solubility characteristics that are essential for its applications in various fields. Solubility plays a critical role in determining how this compound interacts in different environments.

Factors Influencing Solubility

The solubility of (2-fluorophenyl)urea can be influenced by several key factors:

  • Polarity: The presence of the fluorine atom increases the polarity of the molecule, facilitating interactions with polar solvents.
  • Hydrogen Bonding: As an urea derivative, (2-fluorophenyl)urea can engage in hydrogen bonding, enhancing its solubility in water.
  • Temperature: Generally, solubility improves with an increase in temperature, affecting how much of the compound can dissolve.

Typical Solubility Behavior

In terms of its solubility behavior, you might find that:

  • (2-Fluorophenyl)urea is soluble in water due to its polar nature and ability to form hydrogen bonds.
  • It is also soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), making it versatile for various chemical reactions.

In conclusion, the solubility of (2-fluorophenyl)urea is an important consideration in its chemical applications, with its ability to dissolve in both polar and non-polar environments enhancing its functionality and usage in synthetic chemistry.

Interesting facts

Interesting Facts about (2-fluorophenyl)urea

(2-fluorophenyl)urea is an intriguing compound that presents a range of biological and chemical significance. As a derivative of urea, this compound possesses unique properties that make it notable in both research and practical applications.

Key Highlights:

  • Pharmaceutical Relevance: (2-fluorophenyl)urea has been studied for its potential therapeutic effects, particularly in the development of anti-cancer and anti-inflammatory agents. Its structure allows for specific interactions with biological targets, making it a subject of research in medicinal chemistry.
  • Role in Organic Synthesis: This compound serves as a valuable building block in organic synthesis. It can participate in various chemical reactions and transformations, thereby facilitating the creation of more complex molecules.
  • Fluorine's Impact: The incorporation of fluorine into organic compounds often alters their reactivity and biological activity. In (2-fluorophenyl)urea, the fluorine atom influences the electronic properties and steric factors, which can enhance its efficacy in biological settings.
  • Research Interest: Scientists continue to investigate the synthesis and application of (2-fluorophenyl)urea. Its ability to act as a ligand in coordination chemistry makes it appealing for studies related to metal complexes and catalysis.

As a chemistry student or scientist, exploring the properties and applications of (2-fluorophenyl)urea opens up pathways to understand the intricate relationships between molecular structure and function. The ongoing research surrounding fluoro-substituted compounds such as this one reflects the dynamic nature of chemical sciences and its impact on various fields, from pharmaceuticals to materials science.

Synonyms
(2-Fluorophenyl)urea
(o-Fluorophenyl)urea
EINECS 211-513-6
Urea, (o-fluorophenyl)-
DTXSID00215854
NSC 204323
DTXCID30138345
211-513-6
656-31-5
2-FLUOROPHENYLUREA
1-(2-fluorophenyl)urea
N-(2-Fluorophenyl)urea
NSC-204323
O-fluorophenylurea
NSC204323
96AN4P4BDX
Urea, N-(2-fluorophenyl)-
SCHEMBL157188
MFCD00014786
STL124181
AKOS000200398
FF77191
MS-11461
CS-0237075
NS00042710
EN300-17760
A835167
Z57028527