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2-Formylbenzenesulfonyl chloride

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Identification
Molecular formula
C7H3ClO3S
CAS number
7352-65-4
IUPAC name
2-formylbenzenesulfonyl chloride
State
State

At room temperature, 2-formylbenzenesulfonyl chloride is typically a solid.

Melting point (Celsius)
38.00
Melting point (Kelvin)
311.15
Boiling point (Celsius)
366.00
Boiling point (Kelvin)
639.15
General information
Molecular weight
204.63g/mol
Molar mass
204.6320g/mol
Density
1.4810g/cm3
Appearence

2-Formylbenzenesulfonyl chloride is a solid compound that can be found in a crystalline form. Its color can range from white to slightly yellowish.

Comment on solubility

Solubility of 2-Formylbenzenesulfonyl Chloride

2-Formylbenzenesulfonyl chloride, a compound with the chemical formula C7H6ClO3S, displays interesting solubility properties that are characteristic of sulfonyl halides. Its solubility can be summarized as follows:

  • Solvents: This compound is generally soluble in organic solvents such as chloroform, dichloromethane, and ethyl acetate. Such solubility is expected due to its non-polar aromatic and sulfonyl groups.
  • Polar Solvents: 2-Formylbenzenesulfonyl chloride is less soluble in water due to its hydrophobic character. The presence of the sulfonyl group does enhance some degree of interaction with polar solvents, but it remains limited.
  • Temperature Influence: Solubility can increase with temperature; thus, higher temperatures may facilitate dissolution in various organic solvents, contributing to better reactivity in synthesis.

In conclusion, while 2-formylbenzenesulfonyl chloride is predominantly soluble in non-polar and some moderately polar organic solvents, it exhibits limited solubility in water, affirming the general behavior of many sulfonyl chlorides. Always consider these factors when utilizing this compound for chemical reactions and applications.

Interesting facts

Interesting Facts about 2-Formylbenzenesulfonyl Chloride

2-Formylbenzenesulfonyl chloride, often recognized in the chemical community for its versatile reactivity and application, is a compound that stands out for several reasons:

  • Structural Uniqueness: This compound features a sulfonyl chloride functional group attached to a benzaldehyde moiety, which makes it a valuable intermediate in the synthesis of various chemical compounds.
  • Reactivity: The presence of the sulfonyl chloride group grants it the ability to engage in nucleophilic substitution reactions. This property is particularly useful in laboratory settings, enabling the efficient transformation of substrates.
  • Applications in Synthesis: 2-Formylbenzenesulfonyl chloride is widely employed in the manufacture of pharmaceuticals and agrochemicals. It can act as a building block for creating more complex molecules.
  • Role in Medicinal Chemistry: Researchers often utilize this compound in the development of bioactive molecules due to its ability to form stable linkages with various nucleophiles, enhancing the pharmacological properties of drug candidates.
  • Innovative Uses: Beyond traditional chemistry, this compound has found its way into materials science, where it contributes to the synthesis of functionalized polymers, showcasing its versatility across different scientific disciplines.

Noteworthy Insights

As a chemist or a student in the field, exploring compounds like 2-formylbenzenesulfonyl chloride is essential for understanding how structural variations can lead to diverse chemical functionalities. The compound exemplifies the principles of reactivity and synthesis in organic chemistry. Notably, in the words of Sir Isaac Newton, “If I have seen further, it is by standing on the shoulders of giants.” This compound is one such giant, offering a platform from which many innovative discoveries can arise.


Synonyms
2-formylbenzene-1-sulfonyl chloride
21639-41-8
O-FORMYLBENZENESULFONYL CHLORIDE
DTXSID80176030
RefChem:855264
DTXCID3098521
885-787-6
2-formylbenzenesulfonyl chloride
MFCD10697733
o-formyl-benzenesulfonylchloride
SCHEMBL1647327
2-formylbenzenesulphonyl chloride
SCHEMBL15166880
SCHEMBL29849654
GSUMVXPZWCITFC-UHFFFAOYSA-N
2-formylbenzene-1-sulfonylchloride
WAA63941
AKOS006240265
AB60361
CS-0252670
EN300-61171
H36365
Z959662504