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N-hydroxyglycine

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Identification
Molecular formula
C2H5NO3
CAS number
4517-94-4
IUPAC name
2-[formyl(hydroxy)amino]acetic acid
State
State
N-hydroxyglycine is a solid at room temperature. It is typically found in a stable, powdered form.
Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
89.07g/mol
Molar mass
89.0670g/mol
Density
2.1100g/cm3
Appearence

N-hydroxyglycine appears as a white crystalline powder. It is generally known for its pure and consistent crystalline structure.

Comment on solubility

Solubility of 2-[formyl(hydroxy)amino]acetic acid

The solubility of 2-[formyl(hydroxy)amino]acetic acid can be influenced by a variety of factors, including its chemical structure, pH, and temperature. This compound features both a carboxylic acid group and an amino group, which contribute to its solubility characteristics.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups, such as –OH (hydroxyl) and –NH2 (amino), tends to enhance solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds can significantly increase solubility. In this compound, the –OH group can engage in hydrogen bonding with solvent molecules.
  • Environment: The solubility may vary with changes in pH. For example, in acidic conditions, the carboxylic acid group may remain protonated, affecting its overall polarity.

As a general observation, compounds with multiple polar groups are often well-soluble in water, while less polar compounds tend to have lower solubility. Therefore, 2-[formyl(hydroxy)amino]acetic acid is likely to demonstrate good solubility in aqueous environments, making it suitable for various biochemical applications.

In summary, the solubility of 2-[formyl(hydroxy)amino]acetic acid can be attributed to:

  1. Presence of multiple polar functional groups
  2. Ability to form hydrogen bonds
  3. Effect of the solution's pH on the compound's ionization state
Interesting facts

Interesting Facts about 2-[formyl(hydroxy)amino]acetic acid

2-[formyl(hydroxy)amino]acetic acid, commonly known as glycine anhydride, is a fascinating compound in the realm of organic chemistry. This compound possesses a range of properties and applications that make it unique and noteworthy. Here are some interesting aspects:

  • Biological Significance: Glycine is the simplest amino acid and plays a crucial role in biological systems. It is a building block of proteins and participates in various metabolic processes.
  • Medical Relevance: Due to its structure, 2-[formyl(hydroxy)amino]acetic acid has potential therapeutic applications. Research has indicated its possible use in the formulation of drugs to treat neurological disorders.
  • Chemo-sensitivity: The compound is known for its interactions with several enzymes, impacting their activity and making it a key interest in biochemical studies.
  • Versatile Applications: Beyond the lab, this compound has implications in the food industry as a flavor enhancer and in the development of functional foods.
  • Research Opportunities: With ongoing studies focusing on its derivative compounds, 2-[formyl(hydroxy)amino]acetic acid serves as a promising lead compound for developing novel therapeutic agents.

In essence, 2-[formyl(hydroxy)amino]acetic acid is not just a simple molecule; it is a vital player in both biological systems and industrial applications. As a student of chemistry or a scientific researcher, understanding its multifaceted roles can lead to exciting discoveries and innovations.

Synonyms
Hadacidin
689-13-4
Asymmetrin
Hadacidine
N-FORMYL-N-HYDROXYGLYCINE
Hadacin
Nfhaa
N-Formyl hydroxyaminoacetic acid
GLYCINE, N-FORMYL-N-HYDROXY-
N-hydroxyformamidoacetic acid
UNII-BFO5P1010A
NSC 72962
BRN 1927168
BFO5P1010A
CHEBI:43040
[formyl(hydroxy)amino]acetic acid
N-formyl-N-hydroxyaminoacetic acid
HADACIDIN [MI]
2-[formyl(hydroxy)amino]acetic acid
NSC 521778
DTXSID1043962
NSC-72962
NSC-521778
(formyl(hydroxy)amino)acetic acid
hadicidine
2-(formyl(hydroxy)amino)acetic acid
DTXCID9023962
2-(N-Hydroxyformamido)acetic acid
N-formyl-N- hydroxyaminoacetic acid
CHEMBL331373
Glycine,N-formyl-N-hydroxy-
Asymmetrin; Hadacidin
SCHEMBL2115651
2-(N-Hydroxyformamido)aceticacid
(Formyl-hydroxy-amino)-acetic acid
BCP31244
BDBM50149248
AKOS006278464
DB02109
NCI60_004270
DB-230505
HY-126055
CS-0090334
NS00068473
Q15303927