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(2-furylmethyleneamino)urea

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Identification
Molecular formula
C6H7N3O2
CAS number
1329-52-4
IUPAC name
(2-furylmethyleneamino)urea
State
State
At room temperature, (2-furylmethyleneamino)urea is found in a solid state. It is commonly handled in its crystalline or powder form.
Melting point (Celsius)
202.00
Melting point (Kelvin)
475.00
Boiling point (Celsius)
251.00
Boiling point (Kelvin)
524.00
General information
Molecular weight
151.14g/mol
Molar mass
151.1390g/mol
Density
1.4500g/cm3
Appearence

(2-furylmethyleneamino)urea typically appears as a crystalline solid. It may have a characteristic color ranging from white to off-white and can exhibit a slight odor typical of organic compounds related to furan rings or urea groups.

Comment on solubility

Solubility of (2-furylmethyleneamino)urea

(2-furylmethyleneamino)urea is an intriguing compound with notable solubility characteristics. As a derivative of urea, it possesses an amine functional group and a furan ring, contributing to its unique solubility profile.

Generally, the solubility of organic compounds like (2-furylmethyleneamino)urea can depend on several factors:

  • Polarity: The presence of polar functional groups tends to enhance solubility in polar solvents such as water. In the case of (2-furylmethyleneamino)urea, its amine group may promote interactions with water molecules.
  • Hydrogen Bonding: Compounds capable of forming hydrogen bonds typically exhibit better solubility in polar solvents. The NH groups in (2-furylmethyleneamino)urea are likely to engage in hydrogen bonding.
  • Temperature: Solubility often increases with temperature. Solutions may become more concentrated as thermal energy provides kinetic energy for solute-solvent interactions.
  • Structural Configuration: The spatial arrangement of functional groups can affect how well the compound dissolves. The furan ring could influence solvation dynamics.

In experimental settings, (2-furylmethyleneamino)urea has shown to have variable solubility depending on the solvent used and the conditions applied. It is essential to perform solubility tests under controlled environments to gain a precise understanding of its behavior.

As quoted in chemistries, "The nature of solubility speaks volumes about the interactions between molecules." Therefore, understanding the solubility of (2-furylmethyleneamino)urea not only highlights its potential utility but also enriches our grasp of molecular chemistry.


Interesting facts

Interesting Facts about (2-furylmethyleneamino)urea

(2-furylmethyleneamino)urea is a fascinating chemical compound that has garnered attention due to its unique structure and potential applications in various fields, particularly in medicinal chemistry and agrochemicals. Here are some noteworthy aspects of this compound:

  • Structural Significance: The presence of the furan ring in the compound contributes to its reactivity and stability. Furan derivatives are known for their aromaticity and electron-rich nature, making them versatile building blocks in organic synthesis.
  • Potential Anticancer Activity: Research has indicated that urea and its derivatives, including (2-furylmethyleneamino)urea, possess antitumor properties. Preliminary studies suggest that it may inhibit the growth of certain cancer cell lines, which opens up possibilities for its use in cancer therapy.
  • Agricultural Applications: This compound could also play a role in agriculture as a bioregulator or a pesticide agent. Compounds with urea moieties often exhibit herbicidal or fungicidal properties, allowing for targeted crop protection.
  • Intermolecular Interactions: Due to its functional groups, (2-furylmethyleneamino)urea can participate in hydrogen bonding and π-π stacking interactions. This feature influences its solubility and potential interaction with biomolecules, which is crucial for drug design.
  • Importance in Synthesis: The compound serves as an important intermediate in the synthesis of various pharmaceuticals and fine chemicals. Its reactivity allows chemists to create more complex molecules through various reactions, providing a platform for innovative chemical processes.

In conclusion, (2-furylmethyleneamino)urea exemplifies how relatively simple compounds can have profound implications in scientific research and industry. As highlighted by its diverse applications, it is a reminder of the intricacies of chemical design and the ever-evolving nature of chemical discovery.

Synonyms
2-Furaldehyde,semicarbazone
SCHEMBL9697563
DTXSID90859726
AKOS017263210
DS-011251
Hydrazinecarboxamide,2-(2-furanylmethylene)-
2-[(Furan-2-yl)methylidene]hydrazine-1-carboxamide