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Glycocyamine

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Identification
Molecular formula
C3H7N3O2
CAS number
352-97-6
IUPAC name
2-guanidinoacetic acid
State
State

At room temperature, 2-guanidinoacetic acid is a solid. It maintains this state under normal conditions of temperature and pressure and does not sublimate easily. Its stability allows it to be handled without special precautions for its physical state.

Melting point (Celsius)
247.00
Melting point (Kelvin)
520.15
Boiling point (Celsius)
309.00
Boiling point (Kelvin)
582.15
General information
Molecular weight
118.11g/mol
Molar mass
118.1110g/mol
Density
0.5700g/cm3
Appearence

2-Guanidinoacetic acid, also known as glycocyamine, appears as a crystalline powder that is colorless to white. It is soluble in water, which gives a colorless to faintly cloudy solution, and is sparingly soluble in alcohol. Its form can resemble that of many amino acids and related compounds, maintaining a crystalline structure at room temperature.

Comment on solubility

Solubility of 2-Guanidinoacetic Acid

2-Guanidinoacetic acid (C3H7N3O2), an amino acid derivative, exhibits notable solubility properties, particularly in polar solvents. Here's what you should know:

  • It is highly soluble in water, enhancing its biological and chemical interactions.
  • The solubility in aqueous solutions is primarily attributed to the presence of its guanidino group, which can effectively engage in hydrogen bonding.
  • In contrast, its solubility in non-polar solvents is relatively low, making it less effective in those environments.

As a result, 2-guanidinoacetic acid is primarily utilized in aqueous formulations, where its solubility facilitates various applications, including its roles in metabolic and pharmacological contexts.

In summary, when considering the solubility of 2-guanidinoacetic acid:

  1. Highly soluble in water
  2. Poorly soluble in non-polar solvents
  3. Effective in aqueous formulations

This solubility behavior is crucial for its functionality in biochemical processes and pharmaceutical applications.

Interesting facts

Interesting Facts about 2-Guanidinoacetic Acid

2-Guanidinoacetic acid, often abbreviated as GAA, is a fascinating compound that plays a significant role in biochemistry and nutrition. Here are some key points that highlight its importance:

  • Precursor to Creatine: GAA is recognized as a vital precursor to creatine, a compound that is integral to energy metabolism in muscles. This makes it particularly interesting for athletes and those engaged in high-intensity training.
  • Potential Health Benefits: Research has suggested that GAA may help improve exercise performance, enhance muscle mass, and prevent age-related muscle loss. This has sparked interest in its use as a dietary supplement.
  • Natural Occurrence: GAA is naturally synthesized in the body from the amino acid arginine and glycine. It can be found in trace amounts in foods such as meat and fish, which are also sources of creatine.
  • Role in Methylation: The compound is involved in the methylation cycle, which is essential for numerous biological processes, including DNA repair and gene expression.
  • Research Frontier: Ongoing studies are examining the effects of GAA supplementation, which may offer new insights into not just athletic performance but also cognitive function and overall metabolic health.

This compound exemplifies how a seemingly simple molecule can have profound implications in sports nutrition and overall health. With the continuous research in this area, GAA stands out as a compound worth watching in both scientific and fitness communities.

Synonyms
glycocyamine
guanidinoacetic acid
352-97-6
Guanidineacetic acid
2-Guanidinoacetic acid
Guanidoacetic acid
N-amidinoglycine
Betacyamine
Guanyl glycine
guanidinoacetate
Betasyamine
Glykocyamin
Guanidylacetic acid
GLYCINE, N-AMIDINO-
Guanidine, (carboxymethyl)-
glycine, N-(aminoiminomethyl)-
N-(Aminoiminomethyl)glycine
N-[AMINO(IMINO)METHYL]GLYCINE
n-amidino-glycine
amidinoglycine
N-carbamimidoylglycine
Acetic acid, ((aminoiminomethyl)amino)-
2-(diaminomethylideneamino)acetic acid
N-(carbamimidoyl)glycine
(carbamimidamido)acetic acid
2-carbamimidamidoacetic acid
NSC 1901
Guanidoacetate
Guanidylacetate
GUANIDINO ACETATE
Guanidineacetate
a-Guanidinoacetate
b-Guanidinoacetate
EINECS 206-529-5
MFCD00004278
N-(aminoiminomethyl)-glycine
beta-Guanidinoacetate
GO52O1A04E
alpha-Guanidinoacetate
a-Guanidinoacetic acid
b-Guanidinoacetic acid
CHEBI:16344
AI3-17119
NSC1901
beta-Guanidinoacetic acid
NSC-1901
(carboxymethyl)-Guanidine
alpha-Guanidinoacetic acid
GLYCOCYAMINE [MI]
NSC-26360
NSC-227847
.alpha.-Guanidinoacetic acid
GLYCOCYAMINE [WHO-DD]
CHEMBL281593
[(aminoiminomethyl)amino]-Acetate
DTXSID50861885
[(aminoiminomethyl)amino]-Acetic acid
2-[[Amino(imino)methyl]amino]acetate
2-[[Amino(imino)methyl]amino]acetic acid
2-((AMINO(IMINO)METHYL)AMINO)ACETIC ACID
NMG
N-(Amino(Imino)Methyl)Glycine
((aminoiminomethyl)amino)-Acetate
N-Guanylglycine
((aminoiminomethyl)amino)-Acetic acid
2-((Amino(imino)methyl)amino)acetate
Acetic acid, [(aminoiminomethyl)amino]-
CHEBI:131444
UNII-GO52O1A04E
Glucocyamine
guanidine acetic acid
GUANIDOACETIC_ACID
bmse000384
Guanidineacetic acid, 99%
Glycine, N-amidino-(8CI)
SCHEMBL33970
2-carbamimidamido-acetic acid
AMIDINOGLYCINE [INCI]
Glycine, N-amidino- (8CI)
GTPL5325
(Diaminomethylenamino)-essigsaure
DTXCID70810739
HMS3604I10
GAA; Glycocyamine; Guanidinoacetate
NSC26360
AC2229
BDBM50021601
NSC227847
s6340
STL164350
AKOS005363765
DB02751
FG23711
HY-W021448
2-[(diaminomethylidene)amino]acetic acid
([Amino(imino)methyl]amino)acetic acid #
AS-10760
SY015122
DB-069193
CS-0040590
G0167
NS00009387
EN300-49151
C00581
Q2740979
Z586248684
N-(Aminoiminomethyl)-glycine;2-[[Amino(imino)methyl]amino]acetic acid;NSC 26360
206-529-5