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Diphosphatidylglycerol

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Identification
Molecular formula
C42H82O13P2
CAS number
2438-81-5
IUPAC name
(2-hexadecanoyloxy-3-phosphonooxy-propyl) hexadecanoate
State
State

At room temperature, diphosphatidylglycerol is typically found in a solid state. It is often encountered in a laboratory setting as a constituent of membranes where it assumes a bilayer form.

Melting point (Celsius)
72.00
Melting point (Kelvin)
345.00
Boiling point (Celsius)
580.00
Boiling point (Kelvin)
853.00
General information
Molecular weight
1302.00g/mol
Molar mass
1 302.0000g/mol
Density
0.9000g/cm3
Appearence

Diphosphatidylglycerol, commonly known as cardiolipin, typically appears as a light yellow powder. It can also exist in lipid bilayers where it plays a crucial role in mitochondrial membrane structure and function.

Comment on solubility

Solubility of (2-hexadecanoyloxy-3-phosphonooxy-propyl) hexadecanoate

The solubility of (2-hexadecanoyloxy-3-phosphonooxy-propyl) hexadecanoate, with the chemical formula C42H82O13P2, can be quite intriguing due to its complex structure. This compound is a type of phospholipid, characterized by long hydrophobic hydrocarbon chains combined with polar headgroups. Here’s what you should consider about its solubility:

  • Hydrophobic vs Hydrophilic: The long hydrophobic chains (hexadecanoyloxy) suggest that this compound might exhibit low solubility in water. Phospholipids typically have a dual nature, where their hydrophilic head can interact with water but their hydrophobic tails resist it.
  • Solvent Compatibility: It is likely more soluble in organic solvents such as chloroform or ethanol, where the non-polar interactions can effectively stabilize the molecule.
  • Concentration Impact: Increased concentration in polar solvents may lead to phase separation or micelle formation, indicating that solubility isn't merely binary (soluble vs insoluble) but more about dynamic equilibrium.
  • Temperature Role: Temperature can greatly affect solubility; generally, higher temperatures may enhance solubility in non-polar solvents.

In summary, the solubility behavior of (2-hexadecanoyloxy-3-phosphonooxy-propyl) hexadecanoate is influenced by its chemical structure, solvent choice, concentration, and temperature. Understanding these factors is essential for those working with this compound in both laboratory and industrial contexts.

Interesting facts

Interesting Facts about (2-hexadecanoyloxy-3-phosphonooxy-propyl) hexadecanoate

(2-hexadecanoyloxy-3-phosphonooxy-propyl) hexadecanoate is a fascinating compound worth exploring due to its unique structure and potential applications. Here are some noteworthy points:

  • Phospholipid Characteristics: This compound embodies properties often associated with phospholipids, which are essential components of cell membranes. Its dual functional groups facilitate interactions within biological systems.
  • Surface Activity: Due to its long hydrocarbon chain, this compound exhibits surfactant properties, which can reduce surface tension in solutions, making it useful in various formulations.
  • Biochemical Relevance: The presence of phosphonoate groups in the structure suggests possible roles in biochemical processes, including signaling pathways within cells, making it a potential candidate for pharmaceutical research.
  • Applications in Drug Delivery: Compounds like this one, with hydrophobic and hydrophilic characteristics, are often investigated for their ability to encapsulate drugs and improve bioavailability, providing avenues for more effective therapeutic interventions.
  • Research Potential: Ongoing studies into amphiphilic compounds (those having both hydrophilic and hydrophobic parts) like this one could lead to advancements in nanotechnology and materials science, particularly in creating better delivery systems for genetic material and therapeutic agents.

In summary, the complex structure of (2-hexadecanoyloxy-3-phosphonooxy-propyl) hexadecanoate not only contributes to its unique physicochemical properties but also highlights its versatility in various scientific fields. From drug formulation to studying cell membranes, its significance is manifold. As one researcher noted, "Understanding amphiphilic compounds opens doors to innovative solutions in medicine and biotechnology."

Synonyms
19698-29-4
1,2-Dipalmitoy
2,3-Bis(palmitoyloxy)propyl dihydrogen phosphate
dipalmitoylphosphatidic acid
Palmitin, 1,2-di-, dihydrogen phosphate
dihexadecanoyl phosphatidic acid
Palmitin, 1,2-di-, phosphate
CHEBI:78105
Hexadecanoic acid, 1-[(phosphonooxy)methyl]-1,2-ethanediyl ester
PA(16:0/16:0)[rac]
1,2-Dipalmitoyl-rac-glycerophosphoric acid
3-(phosphonooxy)propane-1,2-diyl dihexadecanoate
(1)-1-[(Phosphonooxy)methyl]-1,2-ethanediyl dihexadecanoate
Hexadecanoic acid, 1-((phosphonooxy)methyl)-1,2-ethanediyl ester
PA(32:0)
EINECS 225-873-7
EINECS 243-238-2
2,3-bis-(Palmitoyloxy)propyl dihydrogen phosphate
CBiol_001831
BSPBio_001456
KBioGR_000176
KBioSS_000176
(1)-2,3-Bis(palmitoyloxy)propyl dihydrogen phosphate
(2-hexadecanoyloxy-3-phosphonooxypropyl) hexadecanoate
SCHEMBL2718544
CHEMBL1606485
KBio2_000176
KBio2_002744
KBio2_005312
KBio3_000351
KBio3_000352
DTXSID00864003
PORPENFLTBBHSG-UHFFFAOYSA-N
Bio1_000117
Bio1_000606
Bio1_001095
Bio2_000176
Bio2_000656
HMS1791I18
HMS1989I18
HMS3402I18
1,2-dipalmitoylglycero-3-phosphate
LMGP10010012
1,2-dihexadecanoylglycero-3-phosphate
IDI1_033926
NCGC00161388-01
NCGC00161388-02
NCGC00161388-03
5129-68-0
PD047005
NS00045440
PA 16:0_16:0
PA(16:0_16:0)
Q27147644