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Dodine

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Identification
Molecular formula
C17H36N4
CAS number
2439-10-3
IUPAC name
2-hexadecylguanidine
State
State

At room temperature, Dodine is a solid. However, due to its relatively low melting point, it can also be found in a semi-solid state under slightly warmer conditions.

Melting point (Celsius)
30.50
Melting point (Kelvin)
303.70
Boiling point (Celsius)
374.00
Boiling point (Kelvin)
647.00
General information
Molecular weight
296.53g/mol
Molar mass
299.5320g/mol
Density
0.9209g/cm3
Appearence

Dodine is typically found as a white crystalline solid. It may also appear in other formulations such as powders or mixed with carriers or solvents for agricultural use. The pure compound is distinctly white, emphasizing its crystalline nature.

Comment on solubility

Solubility of 2-hexadecylguanidine

2-hexadecylguanidine, known for its long hydrocarbon chain, displays notable solubility characteristics that can be influenced by various factors. Its solubility behavior can be described as follows:

  • Hydrophobic Nature: The long hexadecyl (C16) chain contributes to its hydrophobic characteristics, making it less soluble in polar solvents such as water.
  • Solubility in Organic Solvents: It exhibits better solubility in non-polar and slightly polar organic solvents, such as:
    • Hexane
    • Toluene
    • Chloroform
  • Temperature Dependence: Like many organic compounds, the solubility of 2-hexadecylguanidine can increase with temperature, making it more soluble in warm organic solvents.

In summary, while 2-hexadecylguanidine is notably insoluble in water, its solubility profile in organic solvents allows for versatile applications in various chemical processes. Understanding its solubility behavior is essential for its effective use in formulations and experimental designs.

Interesting facts

Interesting Facts about 2-Hexadecylguanidine

2-Hexadecylguanidine is a fascinating compound that plays a significant role in various fields, particularly in materials science and biochemistry. Here are some intriguing insights about this compound:

  • Unique Structure: The compound features a long hydrophobic hexadecyl chain attached to the guanidine structure, which grants it unique amphiphilic properties. This dual nature allows it to interact with both polar and non-polar environments.
  • Biological Applications: 2-Hexadecylguanidine is being explored for its potential antibacterial properties. Research has indicated that compounds with long-chain hydrophobic tails can disrupt microbial membranes, leading to enhanced antimicrobial activity.
  • Cell Penetration: The hydrophobic nature of 2-hexadecylguanidine allows for easier penetration through lipid bilayers, making it a valuable candidate for drug delivery systems. Its ability to transport therapeutic agents across cell membranes is being actively researched.
  • Surfactant Properties: This compound also exhibits surfactant characteristics, which can be utilized in various formulations, including emulsions and foams. This trait is particularly useful in the cosmetic and pharmaceutical industries.
  • Environmental Impact: Studies are ongoing to assess the environmental sustainability of 2-hexadecylguanidine, as the long-chain alkyl groups can alter the behavior of biological systems and ecosystems.

In summary, 2-hexadecylguanidine is not just a simple organic compound; it represents a bridge between chemistry and its practical applications in health and industry. As research continues, we may uncover even more innovative uses for this intriguing substance.

Synonyms
SCHEMBL1069234
SCHEMBL10879354