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Tapentadol hydrochloride

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Identification
Molecular formula
C14H23NO2 • HCl
CAS number
175591-09-0
IUPAC name
(2-hydroxy-1-methyl-2-phenyl-ethyl)-(2-phenylpropyl)ammonium;chloride
State
State

At room temperature, Tapentadol hydrochloride exists as a solid. Due to its crystalline nature, it maintains this solid-state without readily absorbing moisture from the air under typical conditions.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
327.90g/mol
Molar mass
327.8950g/mol
Density
1.1600g/cm3
Appearence

Tapentadol hydrochloride typically appears as a white to off-white crystalline powder. This appearance can slightly vary depending on purity and manufacturing processes, but it generally maintains a uniform texture and color.

Comment on solubility

Solubility of (2-hydroxy-1-methyl-2-phenyl-ethyl)-(2-phenylpropyl)ammonium;chloride

The solubility of (2-hydroxy-1-methyl-2-phenyl-ethyl)-(2-phenylpropyl)ammonium;chloride is influenced by its unique molecular structure, which contains both hydrophilic and hydrophobic elements. The presence of the ammonium group enhances its potential for solubility in water; however, the bulky phenyl groups can hinder this process to some extent. Key points to consider include:

  • Water Solubility: This compound is likely to exhibit moderate water solubility due to the ionic nature of the ammonium chloride component.
  • Organic Solvents: It should have good solubility in organic solvents, as the hydrophobic phenyl groups can interact favorably with non-polar solvents.
  • Temperature Dependence: Solubility may increase with temperature, a typical behavior for many salts, which can help in dissolution processes.

In conclusion, while the solubility will be enhanced by the ionic ammonium component, the presence of hydrophobic characteristics from the phenyl groups introduces complexity that can reduce solubility in polar solvents. Understanding these factors is essential for applications in various chemical processes.

Interesting facts

Interesting Facts about (2-hydroxy-1-methyl-2-phenyl-ethyl)-(2-phenylpropyl)ammonium;chloride

The compound known as (2-hydroxy-1-methyl-2-phenyl-ethyl)-(2-phenylpropyl)ammonium;chloride exhibits a fascinating blend of properties that make it a subject of interest in both organic chemistry and pharmacology. Here are some intriguing aspects:

  • Quaternary Ammonium Compounds: This compound falls under the category of quaternary ammonium compounds, which means it features a positively charged nitrogen atom bonded to four organic groups. These compounds are renowned for their antimicrobial properties.
  • Pharmacological Relevance: Due to its structural characteristics, this compound could potentially play a role in the development of pharmacological agents, especially as a local anesthetic or muscle relaxant, owing to its ammonium functionality.
  • Synthesis Potential: The synthetic pathways to create this compound are quite fascinating. Through various methods of alkylation and hydroxylation, chemists can fine-tune its properties, making it an ideal candidate for study in synthetic chemistry.
  • Biological Applications: Research indicates that compounds like this may have applications in drug delivery systems, particularly because of their solubility and ability to cross biological membranes efficiently.
  • Structure-Activity Relationship (SAR): The presence of hydroxy groups in the structure can significantly affect the compound's reactivity and biological activities. Analyzing SAR can lead to better understanding and optimization of its functionalities.

In summary, (2-hydroxy-1-methyl-2-phenyl-ethyl)-(2-phenylpropyl)ammonium;chloride is not only intriguing due to its complex molecular structure but also due to its potential applications in modern chemistry and medicine. As researchers delve deeper into its properties, it is likely that even more exciting uses will be developed.

Synonyms
BS-40
alpha-(1-((beta-Methylphenethyl)amino)ethyl)benzyl alcohol hydrochloride
BENZYL ALCOHOL, alpha-(1-((beta-METHYLPHENETHYL)AMINO)ETHYL)-, HYDROCHLORIDE
18864-12-5