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2-Hydroxy-1-methylquinolin-4-one

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Identification
Molecular formula
C10H9NO2
CAS number
1823-00-7
IUPAC name
2-hydroxy-1-methyl-quinolin-4-one
State
State

At room temperature, 2-hydroxy-1-methylquinolin-4-one is in a solid state. It is a crystalline compound.

Melting point (Celsius)
231.00
Melting point (Kelvin)
504.15
Boiling point (Celsius)
538.40
Boiling point (Kelvin)
811.60
General information
Molecular weight
175.18g/mol
Molar mass
175.1840g/mol
Density
1.3000g/cm3
Appearence

2-Hydroxy-1-methylquinolin-4-one is typically a solid substance at room temperature. It can appear as a yellow to yellow-green crystalline powder or solid.

Comment on solubility

Solubility of 2-hydroxy-1-methyl-quinolin-4-one

The solubility of 2-hydroxy-1-methyl-quinolin-4-one, a chemical compound known for its intriguing structure and activity, can be influenced by various factors. Here are some key points to consider regarding its solubility:

  • Polarity: The presence of a hydroxyl group (–OH) contributes to its polarity, which plays a significant role in its ability to dissolve in water.
  • Solvent Compatibility: This compound may exhibit greater solubility in organic solvents such as methanol, ethanol, or dimethyl sulfoxide (DMSO) compared to water.
  • Temperature Effects: Like many organic compounds, solubility can increase with temperature. Therefore, higher temperatures may improve the dissolution of the compound in a given solvent.
  • pH Sensitivity: The solubility of 2-hydroxy-1-methyl-quinolin-4-one can also be affected by the pH of the solution, particularly due to its hydroxyl group which can partake in acid-base reactions.

It is noteworthy to mention that the solubility characteristics make 2-hydroxy-1-methyl-quinolin-4-one an exciting compound for various applications, including biological assessments, where understanding solubility can aid in its practical use. As stated, "Solubility is life." This quote underscores the importance of solubility in determining how compounds behave in complex environments.

Interesting facts

Exploring 2-hydroxy-1-methyl-quinolin-4-one

2-hydroxy-1-methyl-quinolin-4-one, also known as 8-hydroxyquinoline, is a fascinating compound that has attracted considerable attention in the fields of chemistry and pharmaceuticals. Here are some interesting facts about this intriguing molecule:

  • Historical Significance: The compound was first synthesized in the early 20th century and quickly found applications in various industrial and medical contexts.
  • Biological Activity: 8-hydroxyquinoline exhibits notable biological properties, including antibacterial, antiviral, and antifungal activities. This makes it a compound of interest for researchers looking to develop new medications.
  • Metal Chelation: One of the most remarkable properties of this compound is its ability to chelate metal ions. It forms stable complexes with metals such as iron and copper, which can be beneficial for treating metal overload conditions in the body.
  • Applications in Analytical Chemistry: Due to its metal-binding capabilities, it is widely used in analytical chemistry as a reagent, particularly in the detection and quantification of metals in various samples.
  • Research Potential: Ongoing research is exploring its potential in cancer therapy, where its ability to interfere with cellular processes may lead to innovative treatment strategies.

As a compound that bridges the gap between organic chemistry and medicinal applications, 2-hydroxy-1-methyl-quinolin-4-one continues to pique the interest of scientists and offers exciting opportunities for future discoveries. As noted by one researcher, “The versatility of 8-hydroxyquinoline opens doors to new avenues in drug design and environmental science.”