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Deferiprone

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Identification
Molecular formula
C6H7NO2
CAS number
30652-11-0
IUPAC name
2-hydroxy-1H-pyridin-4-one
State
State

At room temperature, Deferiprone is typically in a solid state, appearing as a powder or crystalline solid.

Melting point (Celsius)
137.50
Melting point (Kelvin)
410.60
Boiling point (Celsius)
259.50
Boiling point (Kelvin)
532.70
General information
Molecular weight
139.13g/mol
Molar mass
139.1100g/mol
Density
1.2990g/cm3
Appearence

Deferiprone is a white to yellowish powder with crystalline properties. It may also appear as a white to off-white solid powder, depending on the purity and sample preparation.

Comment on solubility

Solubility of 2-hydroxy-1H-pyridin-4-one

2-hydroxy-1H-pyridin-4-one, commonly referred to as a pyridinone derivative, exhibits interesting solubility characteristics that can vary depending on the solvent used.

Solubility Profile:

  • In Water: This compound is generally considered to be moderately soluble in water, thanks to its hydroxyl group (-OH) that can engage in hydrogen bonding.
  • In Organic Solvents: It tends to be more soluble in polar organic solvents, such as alcohols and acetone, owing to its ability to interact with solvent molecules.
  • Temperature Dependency: Its solubility can be influenced by temperature, with higher temperatures typically leading to increased solubility.

Hey there! If you're experimenting with this compound, keep in mind that the pH of the solution can also play a significant role in its solubility. As pH increases, the solubility may alter due to deprotonation of the hydroxyl group.

In conclusion, for practical applications, understanding the unique solubility properties of 2-hydroxy-1H-pyridin-4-one can help in selecting appropriate solvents and conditions for your chemical processes.

Interesting facts

Interesting Facts about 2-Hydroxy-1H-pyridin-4-one

2-Hydroxy-1H-pyridin-4-one, also known as 4-hydroxy-2(1H)-pyridinone, is a fascinating compound that belongs to the class of heterocyclic organic compounds. Here are some intriguing aspects about this chemical:

  • Therapeutic Applications: This compound has garnered significant attention for its potential therapeutic uses. It serves as a potent chelator for metal ions, especially iron, making it a candidate for treating conditions like thalassemia and other iron overload disorders.
  • Biological Importance: Its metal-binding properties are crucial as they help in regulating metal homeostasis in biological systems, which is vital for numerous cellular processes.
  • Antioxidant Properties: Recent studies have highlighted its role as an antioxidant, suggesting that it can scavenge free radicals, thus potentially contributing to protective effects against oxidative stress-related diseases.
  • Research Interest: In the realm of academic research, 2-hydroxy-1H-pyridin-4-one is a compound of interest for studying its interactions with various transition metals and its implications in drug development.
  • Derivatives Exploration: The study of its derivatives is equally captivating, with researchers investigating modifications that can enhance its biological activity or bind select metals more effectively.
  • Coordination Chemistry: The compound's ability to coordinate with metal ions leads to interesting applications in coordination chemistry, contributing to the development of new materials and catalysts.

As a reminder, the investigation into compounds like 2-hydroxy-1H-pyridin-4-one not only expands our understanding of chemistry but also opens avenues for innovation in pharmaceuticals and materials science. Exploring its properties and applications makes it a valuable subject of study in modern chemistry.