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Tramadol Hydrochloride

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Identification
Molecular formula
C16H26ClNO2
CAS number
27203-92-5
IUPAC name
[2-hydroxy-2-(3-hydroxyphenyl)ethyl]-methyl-ammonium;chloride
State
State

At room temperature, tramadol hydrochloride is typically in a solid state as a crystalline powder.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.00
Boiling point (Celsius)
254.40
Boiling point (Kelvin)
527.50
General information
Molecular weight
299.85g/mol
Molar mass
299.8480g/mol
Density
1.2670g/cm3
Appearence

Tramadol hydrochloride appears as a white to off-white crystalline powder. It is odorless or nearly so and is readily soluble in water and methanol, while sparingly soluble in acetone or ether.

Comment on solubility

Solubility of [2-hydroxy-2-(3-hydroxyphenyl)ethyl]-methyl-ammonium;chloride

The solubility of the compound [2-hydroxy-2-(3-hydroxyphenyl)ethyl]-methyl-ammonium;chloride presents some intriguing characteristics:

  • Polarity: Due to the presence of hydroxyl groups and a quaternary ammonium structure, this compound tends to be highly polar.
  • Water Solubility: It is generally expected to be soluble in water, thanks to its ionic nature and the ability to form hydrogen bonds.
  • Solvent Dependency: The solubility may vary significantly in organic solvents versus aqueous solutions.
  • Temperature Influence: Increasing the temperature often enhances solubility for many organic compounds, and this may also apply here.

As noted, the ability of [2-hydroxy-2-(3-hydroxyphenyl)ethyl]-methyl-ammonium;chloride to dissolve is influenced by both its chemical structure and the surrounding solvent environment. To fully understand its solubility profile, one would need to consider factors such as ionic strength, pH, and the presence of other solutes in the solution.

In summary, with its significant polar characteristics, this compound is likely to show good solubility in water, making it an interesting candidate for various applications that require aqueous solutions.

Interesting facts

Interesting Facts about [2-hydroxy-2-(3-hydroxyphenyl)ethyl]-methyl-ammonium; chloride

This fascinating compound, known for its complex structure and unique functionality, is a member of the ammonium salts family. Here are some intriguing aspects which highlight its significance in chemistry:

  • Pharmaceutical Potential: The hydroxyl groups present in the structure often play a crucial role in pharmacological activities. Such compounds show promise in medicinal chemistry, particularly in the development of drugs targeting various biological pathways.
  • Structure-Activity Relationship: Understanding the correlation between its chemical structure and biological activity can lead to innovations in drug design. Researchers explore how changes in the hydroxyphenyl group influence binding affinities and overall effectiveness.
  • Applications in Material Science: This compound may also have utility in developing new materials, particularly in polymers where ionic interactions can be leveraged to improve material properties like conductivity and stability.
  • Quantum Chemistry Investigations: The intricate electronic and steric interactions within this structure are of interest in computational chemistry. Researchers often employ quantum mechanical methods to predict its behavior in various chemical contexts.
  • Environmental Relevance: Investigating the environmental impact and degradation pathways of such compounds can provide insights into their fate in ecosystems, promoting sustainability in chemical manufacturing.

In summary, the study of [2-hydroxy-2-(3-hydroxyphenyl)ethyl]-methyl-ammonium; chloride extends beyond mere chemistry; it touches upon fields such as pharmacology, material science, and environmental science. The ongoing research continues to unveil the potential applications and significance of this compound in our understanding of chemical interactions and innovations.