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Synephrine hydrochloride

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Identification
Molecular formula
C9H14ClNO2
CAS number
5985-28-4
IUPAC name
[2-hydroxy-2-(4-hydroxy-3,5-dimethoxy-phenyl)ethyl]-methyl-ammonium;chloride
State
State

At room temperature, synephrine hydrochloride is in a solid state, typically found as a crystalline powder.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
83.00
Boiling point (Kelvin)
356.15
General information
Molecular weight
219.67g/mol
Molar mass
219.7000g/mol
Density
1.3050g/cm3
Appearence

Synephrine hydrochloride typically appears as a white to off-white crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility Characteristics

The compound [2-hydroxy-2-(4-hydroxy-3,5-dimethoxy-phenyl)ethyl]-methyl-ammonium; chloride exhibits specific solubility properties that are essential for its applications in various fields. Understanding these solubility characteristics is vital for effective utilization.

General Solubility Insights

Overall, this compound is likely to be:

  • Soluble in polar solvents: Given the presence of multiple hydroxyl groups and the quaternary ammonium ion, the compound shows a propensity to dissolve in water and other polar solvents.
  • Less soluble in non-polar solvents: The steric effects of the bulky dimethoxy substituents may hinder solubility in organic solvents like hexane or benzene.

Factors Influencing Solubility

Several factors contribute to the solubility of this compound:

  • Hydrogen bonding: The hydroxyl groups are capable of hydrogen bonding, enhancing solubility in aqueous solutions.
  • Ionic interactions: As a quaternary ammonium chloride, the ionic nature can further aid in solubilizing this compound in water.
  • Temperature: Increased temperature typically enhances the solubility of compounds, which may also apply here.

In conclusion, the solubility of [2-hydroxy-2-(4-hydroxy-3,5-dimethoxy-phenyl)ethyl]-methyl-ammonium; chloride is greatly influenced by its structural features, with a clear predilection for polar environments. As noted, "solubility is not just a property, but the key to a compound's mobility and reactivity." Understanding its solubility behavior opens up pathways for further research and applications.

Interesting facts

Interesting Facts about [2-hydroxy-2-(4-hydroxy-3,5-dimethoxy-phenyl)ethyl]-methyl-ammonium;chloride

This fascinating compound, with its complex molecular structure, has caught the attention of chemists and biologists alike. Here are some captivating aspects:

  • Pharmacological Importance: This compound serves as a significant subject of study due to its potential therapeutic applications. Its structural features may impart antioxidant and anti-inflammatory properties, making it a candidate for pharmaceutical research.
  • Natural Product Derivative: The compound contains a phenolic ring, which is commonly found in various natural products. These derivatives often play crucial roles in plant biochemistry, contributing to functions such as pigmentation and defense mechanisms.
  • Quaternary Ammonium Compound: Being a quaternary ammonium salt, this compound possesses unique properties as a surfactant and can be used in formulations to enhance solubility and stability. Surfactants are vital in various industrial and biological applications.
  • Insights into Structure-Activity Relationship: The presence of methoxy groups in the phenyl ring can provide insights into the structure-activity relationship (SAR) of similar compounds. Understanding these relationships can guide the design of new compounds with improved activity.
  • Chemical Behavior: The hydroxyl groups present in the structure enhance its reactivity, permitting interactions with a wide range of biomolecules. This property is essential for its potential role in drug design.

In the realm of chemistry, understanding such compounds sheds light on important biological processes and paves the way for innovative therapeutic strategies. As our knowledge of these types of compounds expands, so too does our ability to harness their potential in both medicine and industry.

Synonyms
Pressamina
Dimethophrine hydrochloride
22775-12-8
AUO1AP3DJR
Dimetofrine HCl
Dimetrophine hydrochloride
[2-hydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)ethyl]-methylazanium;chloride
Dimetofrina cloridrato
Dimetofrina cloridrato [Italian]
4-Hydroxy-3,5-dimethoxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride
UNII-AUO1AP3DJR
EINECS 245-212-6
(+-)-1-(3,5-Dimethoxy-4-hydroxyphenyl)-2-(methylamino)ethanol hydrochloride
(+-)-1-(4-Hydroxy-3,5-dimethoxyphenyl)-2-methylaminoethanol hydrochloride
(+-)-1-(4-Idrossi-3,5-dimetossifenil)-2-metilaminoetanolo cloridrato [Italian]
(+-)-4-Hydroxy-3,5-dimethoxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride
Benzenemethanol, 4-hydroxy-3,5-dimethoxy-alpha-((methylamino)methyl)-, hydrochloride
(+-)-1-(4-Idrossi-3,5-dimetossifenil)-2-metilaminoetanolo cloridrato
Benzyl alcohol, 4-hydroxy-3,5-dimethoxy-alpha-((methylamino)methyl)-, hydrochloride