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Betahistine hydrochloride

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Identification
Molecular formula
C8H13ClNO2
CAS number
5638-76-6
IUPAC name
[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methyl-ammonium;chloride
State
State

At room temperature, Betahistine hydrochloride is in a crystalline solid state.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
348.00
Boiling point (Kelvin)
621.15
General information
Molecular weight
209.70g/mol
Molar mass
209.7030g/mol
Density
1.2620g/cm3
Appearence

Betahistine hydrochloride typically appears as a white to off-white crystalline powder. It is very soluble in water, soluble in alcohol, and practically insoluble in chloroform and ether.

Comment on solubility

Solubility of [2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methyl-ammonium;chloride

The solubility of [2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methyl-ammonium;chloride can be influenced by a variety of factors, including pH, temperature, and the presence of ions in solution.

Key Factors Affecting Solubility:

  • Ionization: As a quaternary ammonium compound, it is likely to have good solubility in polar solvents like water due to its ionic nature.
  • Hydrophobic and Hydrophilic Balance: The presence of the 4-hydroxyphenyl group may enhance interactions with water, while the hydroxyethyl component contributes to its overall hydrophilicity.
  • Temperature: Increased temperature typically leads to enhanced solubility for many ionic compounds; thus, heating may facilitate the dissolution process.

In summary, one might expect this compound to exhibit substantial solubility in aqueous environments, primarily due to its ionic characteristics. As one researcher noted, "the balance of hydrophobic and hydrophilic groups within a molecule plays a pivotal role in determining its solubility profile." Therefore, understanding its behavior in different solvents and conditions is crucial for its practical applications.

Interesting facts

Interesting Facts about [2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methyl-ammonium;chloride

This compound, known for its unique structure and properties, is an important member of the family of ammonium salts. The presence of the hydroxyl groups and the phenolic structure in its molecular design gives it distinctive characteristics that are fascinating from both a chemical and practical standpoint.

Key Features:

  • Dual Functionality: The compound features both a hydroxyl group and a phenyl ring, making it capable of participating in hydrogen bonding and various chemical interactions.
  • Biological Relevance: Due to its structural similarities to certain biologically active compounds, it can serve as a model for studying pharmaceuticals and biochemical pathways.
  • Solubility: As an ammonium salt, it generally displays a high degree of solubility in water, which is crucial for applications in biological systems and drug formulation.

Applications:

  • Pharmaceutical Industry: The compound's unique characteristics may be investigated for their potential therapeutic benefits.
  • Chemical Research: Its versatile structure makes it an excellent candidate for studies focusing on reaction mechanisms and compound interactions.
  • Cosmetic Formulations: The hydroxyl groups offer moisturizing properties, making it relevant in the beauty industry for skin care products.

In conclusion, the study of [2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methyl-ammonium;chloride not only enhances our understanding of ammonium salts but also opens doors to innovative applications in various fields. As chemists delve deeper into its properties, they may uncover even more uses and significance of this compound in both industrial and academic research.

Synonyms
4-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride
[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methylazanium;chloride