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Phenylephrine hydrochloride

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Identification
Molecular formula
C9H14ClNO2
CAS number
61-76-7
IUPAC name
[2-hydroxy-2-(4-nitrophenyl)ethyl]-isopropyl-ammonium;chloride
State
State

At room temperature, Phenylephrine hydrochloride is in a solid state. It is usually available in powder form and is stable under standard conditions.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.00
Boiling point (Celsius)
246.00
Boiling point (Kelvin)
519.00
General information
Molecular weight
203.67g/mol
Molar mass
203.6730g/mol
Density
1.1610g/cm3
Appearence

Phenylephrine hydrochloride appears as a white or almost white crystalline powder. It is freely soluble in water and soluble in alcohol, which makes it useful for pharmaceutical applications.

Comment on solubility

Solubility of [2-hydroxy-2-(4-nitrophenyl)ethyl]-isopropyl-ammonium;chloride

The solubility of a compound such as [2-hydroxy-2-(4-nitrophenyl)ethyl]-isopropyl-ammonium;chloride can be quite intriguing due to its unique structural elements. Here are some key points regarding its solubility:

  • Solvent Dependence: The solubility of this compound may vary significantly depending on the solvent used. For instance, it is expected to be more soluble in polar solvents due to its quaternary ammonium nature.
  • Hydrophilicity: The presence of the hydroxyl group (-OH) enhances hydrophilicity, making it soluble in water. Hydrophilic compounds typically exhibit better solubility in polar mediums.
  • Influence of Ionic Nature: As a chloride salt, it often indicates a degree of ionic character which can further contribute to its solubility in aqueous solutions.
  • Temperature Effects: Generally, increasing the temperature can enhance the solubility of solids in liquids, and this compound may be no exception.
  • Potential Limitations: While solubility is favored in certain environments, different pH levels or ionic strengths of the solution could impact solubility behavior.

In conclusion, the solubility of [2-hydroxy-2-(4-nitrophenyl)ethyl]-isopropyl-ammonium;chloride reflects a complex interplay of its structural characteristics and the environmental conditions. To fully understand its solubility profile, experimental data in various solvent systems and conditions would be essential.

Interesting facts

Interesting Facts about [2-hydroxy-2-(4-nitrophenyl)ethyl]-isopropyl-ammonium;chloride

This compound, often referred to in literature as a quaternary ammonium salt, is notable for its unique structure and applications in various fields. Here are some intriguing aspects:

  • Pharmacological Significance: Compounds like this one are frequently studied for their role in drug development, particularly in the area of antimicrobial agents. The presence of nitrophenyl groups can enhance biological activity.
  • Electrophilic Properties: The 4-nitrophenyl moiety can act as an electron-withdrawing group, making the compound an interesting candidate for substitution reactions and helping to modulate reactivity.
  • Solubility and Stability: The quaternary ammonium structure offers enhanced solubility in various solvents, which makes it versatile for use in formulations across pharmaceutical and agrochemical industries.
  • Research Applications: This compound serves as a model in studies involving cationic surfactants, linking to properties that can be exploited in drug delivery systems and antibacterial formulations.
  • Potency and Activity: Its design allows for modulation of pharmacokinetic properties, potentially leading to improved therapeutic outcomes in targeted drug therapies.

As a scientist or chemistry student, understanding compounds like [2-hydroxy-2-(4-nitrophenyl)ethyl]-isopropyl-ammonium;chloride is crucial. The intersection of organic chemistry, pharmacology, and materials science offers a fascinating playground for innovation and discovery.

In the words of renowned chemist Robert H. Grubbs, "It is the interplay of science and the invisible that drives us to explore new realms of knowledge." This compound is a prime example of how chemistry can lead to advancements in health and technology.