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Octyl-phosphocholine

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Identification
Molecular formula
C32H68NO6P
CAS number
3109-63-5
IUPAC name
2-[hydroxy-(2-methoxy-3-octadecoxy-propoxy)phosphoryl]oxyethyl-trimethyl-ammonium
State
State

At room temperature, Octyl-phosphocholine is typically found as a liquid. It is a zwitterionic surfactant and is soluble in water and various organic solvents.

Melting point (Celsius)
-5.00
Melting point (Kelvin)
268.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
504.77g/mol
Molar mass
504.7690g/mol
Density
1.0050g/cm3
Appearence

Octyl-phosphocholine typically appears as a clear to slightly yellowish liquid. It might also be encountered in the form of a viscous solution. The compound is known for its surfactant properties, which may influence its viscosity and appearance under different conditions.

Comment on solubility

Solubility of 2-[hydroxy-(2-methoxy-3-octadecoxy-propoxy)phosphoryl]oxyethyl-trimethyl-ammonium

The solubility of the compound 2-[hydroxy-(2-methoxy-3-octadecoxy-propoxy)phosphoryl]oxyethyl-trimethyl-ammonium (C32H68NO6P) is influenced by several key factors:

  • Hydrophilic vs. Hydrophobic Nature: This compound exhibits both hydrophilic and hydrophobic characteristics, primarily owing to the presence of the ammonium group and the long hydrocarbon chain.
  • Solvent Compatibility: Typically, compounds with long alkyl chains, such as this one, tend to be more soluble in non-polar organic solvents. In contrast, they may present limited solubility in polar solvents like water.
  • Temperature Influence: The solubility of this compound is likely to increase with temperature, as higher temperatures can disrupt the packing of molecules, enhancing interaction with solvent particles.

Moreover, it is essential to consider:

  • Concentration Dependency: As the concentration of the compound increases, its solubility might reach a saturation point, beyond which no further dissolution occurs.
  • Interactions with Solvents: The nature of the solvent can significantly affect solubility; for example, polar protic solvents may enhance the interaction with the ammonium group.

In summary, understanding the solubility of this compound requires a careful evaluation of its molecular structure and the solvent environment. Its unique properties make it a fascinating subject for further study in the context of solubility dynamics.

Interesting facts

Interesting Facts about 2-[hydroxy-(2-methoxy-3-octadecoxy-propoxy)phosphoryl]oxyethyl-trimethyl-ammonium

This compound exhibits a fascinating blend of organic and inorganic chemistry, showcasing the versatility of phosphonium compounds. Phosphorus compounds like this play crucial roles in a range of applications, particularly in the fields of biochemistry and materials science.

Key Characteristics:

  • Ammonium Structure: The presence of a trimethylammonium group imparts cationic properties, allowing it to interact favorably with negatively charged surfaces, which makes it valuable in formulations such as surfactants and emulsifiers.
  • Phosphate Group: The phosphoryl group in this compound is significant for its involvement in biological processes, notably in energy transfer mechanisms similar to those seen in ATP (adenosine triphosphate).
  • Hydrophobic and Hydrophilic Properties: The long octadecoxy chain provides hydrophobic characteristics, while the trimethylammonium and hydroxyl groups contribute to hydrophilicity. This duality enhances its performance in various applications including drug delivery systems and surfactants.
  • Potential Uses: Given its unique properties, this compound could serve as a promising agent in drug formulation, helping in the targeted delivery of therapeutic agents into cells.

The synthesis of such compounds often involves intricate methods, demonstrating the sophisticated techniques used in modern chemistry. As Albert Einstein once said, "Everything should be made as simple as possible, but no simpler." This reminds us that understanding complex chemical structures necessitates simplification to contribute effectively to scientific advancements.

In summary, 2-[hydroxy-(2-methoxy-3-octadecoxy-propoxy)phosphoryl]oxyethyl-trimethyl-ammonium serves as an intriguing example of how tailored molecular design can lead to innovative materials with diverse applications in both industry and healthcare.

Synonyms
144615-60-1
3-Octadecyloxy-2-methoxypropylphosphonocholine
2-[hydroxy-(2-methoxy-3-octadecoxypropoxy)phosphoryl]oxyethyl-trimethylazanium
65492-82-2
130157-42-5
1-Octadecyl-2-methylphosphorylcholine
Choline, 1-octadecyl-2-methoxy-3-phosphoryl-
PHOSPHORYLCHOLINE, 1-OCTADECYL-2-METHYL- (ALP)
SDZ-62-826
2-[hydroxy-(2-methoxy-3-octadecoxy-propoxy)phosphoryl]oxyethyl-trimethyl-ammonium
AlP
CHEMBL60166
SCHEMBL8251942
HSCI1_000364
NCI60_002816
2-((Hydroxy(2-methoxy-3-(octadecyloxy)propoxy)phosphoryl)oxy)-N,N,N-trimethylethanaminium
2-Methoxy-3-(octadecyloxy)propyl 2-(trimethyl-lambda~5~-azanyl)ethyl hydrogen phosphate
3,5, 9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N, N-trimethyl-, hydroxide, inner salt, 4-oxide