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Remdesivir

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Identification
Molecular formula
C27H35N6O8P
CAS number
1809249-37-3
IUPAC name
2-hydroxy-2-oxo-acetate;1-[3-methoxy-4-[4-[3-(2-methoxyphenoxy)pyrrolidin-1-ium-1-yl]butoxy]phenyl]ethanone
State
State

Remdesivir is typically processed into an aqueous solution for medical applications, frozen or lyophilized, making it a solid in its stable storage form, but it becomes a liquid when reconstituted for use.

Melting point (Celsius)
121.00
Melting point (Kelvin)
394.15
Boiling point (Celsius)
763.10
Boiling point (Kelvin)
1 036.25
General information
Molecular weight
602.59g/mol
Molar mass
602.5850g/mol
Density
1.5140g/cm3
Appearence

Remdesivir appears as a white to off-white powder in its pure form. It is generally odorless, and the compound is often processed into a formulated solution for intravenous administration.

Comment on solubility

Solubility of 2-hydroxy-2-oxo-acetate; 1-[3-methoxy-4-[4-[3-(2-methoxyphenoxy)pyrrolidin-1-ium-1-yl]butoxy]phenyl]ethanone

The solubility of the compound 2-hydroxy-2-oxo-acetate; 1-[3-methoxy-4-[4-[3-(2-methoxyphenoxy)pyrrolidin-1-ium-1-yl]butoxy]phenyl]ethanone is significantly influenced by its complex structure and the presence of various functional groups. As a result, its solubility behavior can be characterized by the following points:

  • Hydrophilicity vs. Lipophilicity: The presence of polar groups such as hydroxyl (-OH) and methoxy (-OCH3) contributes to enhanced solubility in polar solvents like water.
  • Ionization: The pyrrolidin-1-ium moiety may enhance solubility in aqueous solution due to its ionic character, increasing solubility when in contact with water.
  • Solvent Interactions: The solubility of this compound can be dependent on the solvent used; it is likely more soluble in organic solvents due to its lipophilic portions.
  • Temperature Effects: As with many organic compounds, solubility may increase with rising temperature, although this can vary depending on the specific interactions in solution.

In conclusion, it is important to note that the intricate balance of hydrophilic and hydrophobic regions contributes to the overall solubility characteristics of this compound. Understanding these interactions is crucial for predicting its behavior in different environments.

Interesting facts

Interesting Facts about 2-Hydroxy-2-oxo-acetate; 1-[3-methoxy-4-[4-[3-(2-methoxyphenoxy)pyrrolidin-1-ium-1-yl]butoxy]phenyl]ethanone

This complex compound, while not extensively studied, opens up a realm of interesting avenues for exploration in the fields of medicinal chemistry and synthetic organic chemistry. Here are some key facts:

  • Structure Diversity: This compound exhibits a unique combination of functional groups that enhance its biological activity and potential therapeutic effects.
  • Pyrrolidine Moiety: The presence of the pyrrolidine ring contributes to interesting stereoelectronic effects, potentially influencing its interactions with biological targets.
  • Biological Activity: Compounds of this nature often hold potential for a variety of biological activities, including anti-inflammatory and analgesic effects, making them of interest in pharmaceutical development.
  • Research Potential: Due to its unique structure, exploring the reactivity and synthesis pathways of this compound could lead to discoveries of new derivatives with enhanced efficacy.
  • Applications: Beyond medicinal applications, this compound structure could inspire new materials in chemical sensors or nanotechnology due to its unique electronic properties.

As a chemistry student or scientist, one might reflect on the importance of such compounds in drug discovery and development. The intricacies of their design and function often lead to breakthrough innovations. As the famous chemist Linus Pauling stated, "The best way to have a good idea is to have a lot of ideas." This compound certainly exemplifies the endless possibilities that arise from complex molecular architectures.


Synonyms
Acetophenone, 3'-methoxy-4'-(4-(3-(o-methoxyphenoxy)-1-pyrrolidinyl)butoxy)-, oxalate (1:1)
3'-Methoxy-4'-(4-(3-(o-methoxyphenoxy)-1-pyrrolidinyl)butoxy)-acetophenone oxalate (1:1)
23026-56-4
RefChem:316940