Skip to main content

Lacosamide

ADVERTISEMENT
Identification
Molecular formula
C13H18N2O3
CAS number
175481-36-4
IUPAC name
2-hydroxy-2-oxo-acetate;2-pyrrolidin-1-ium-1-ylethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate
State
State

At room temperature, lacosamide is present as a solid.

Melting point (Celsius)
143.00
Melting point (Kelvin)
416.15
Boiling point (Celsius)
491.00
Boiling point (Kelvin)
764.15
General information
Molecular weight
250.66g/mol
Molar mass
250.6620g/mol
Density
1.0840g/cm3
Appearence

Lacosamide appears as a white to off-white crystalline powder. It is practically insoluble in water, soluble in acetonitrile, and sparingly soluble in anhydrous ethanol.

Comment on solubility

Solubility of 2-Hydroxy-2-oxo-acetate; 2-pyrrolidin-1-ium-1-ylethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate

The solubility of this complex compound can be intriguing due to its unique chemical structure, which can impart particular solvation characteristics. Key factors influencing its solubility include:

  • Polarity: The presence of polar functional groups, such as hydroxyl (–OH) and carbonyl (C=O), typically enhances the solubility of compounds in polar solvents like water.
  • Hydrophobic Character: The naphthyl and tetrahydrofuran components suggest a certain degree of hydrophobicity, which may reduce solubility in water but could enhance solubility in organic solvents.
  • Ionization: As a pyrrolidinium salt, the compound may exhibit good solubility in polar aprotic solvents as the ionic character can yield favorable interactions, particularly in suitable solvent environments.
  • Temperature: Solubility is often temperature-dependent; increases in temperature may enhance the solubility of this compound in various solvents.

Overall, while the solubility can vary widely based on the solvent and conditions, it can be noted that polar solvents may effectively dissolve this particular complex compound due to the combination of polar and non-polar interactions. As with many compounds, testing in specific solvents yields the best understanding of practical solubility.

Interesting facts

Interesting Facts about 2-Hydroxy-2-oxo-acetate; 2-pyrrolidin-1-ium-1-ylethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate

This compound is a fascinating example of a complex organic molecule that combines a range of functionalities, making it an interesting subject of study in both organic chemistry and materials science. Here are some notable aspects of this compound:

  • Diverse Structure: The compound features a unique combination of a pyrrolidine ring and a tetrahydrofuran structure, which contributes to its biological and chemical properties. Such structures are often seen in natural products and pharmaceutical compounds.
  • Applications in Pharmaceuticals: Given its elaborate structure, this substance may exhibit interesting biological activity. Compounds with similar frameworks are often investigated for their potential as drug candidates, particularly in areas such as neuropharmacology and cancer treatment.
  • Synthetic Utility: The presence of functional groups such as hydroxyl and carbonyl within the molecule suggests potential reactivity, allowing chemists to propose synthetic pathways for creating derivatives of this compound.
  • Research Opportunities: The intricate design of this compound opens up avenues for research into its mechanism of action, interactions with biological targets, and stability under various conditions.
  • Multifunctionality: The compound possesses features that may allow it to function as both a chiral building block and a versatile intermediate, enhancing its relevance in the synthesis of complex natural products.

As chemistry students or researchers delve deeper into the exploration of this compound, they may uncover valuable insights into its reactivity and potential applications in various fields. Each investigation could lead to new discoveries that highlight the intricate balance of structure and function in organic compounds. As the renowned chemist Linus Pauling once stated, "The best way to have a good idea is to have lots of ideas." This serves as a reminder that the study of such compounds can inspire innovation and advancement in chemical sciences.

Synonyms
alpha-(1-Naphthylmethyl)tetrahydro-2-furanpropionic acid 2-(1-pyrrolidinyl)ethyl ester oxalate
2-Furanpropionic acid, tetrahydro-alpha-(1-naphthylmethyl)-, 2-(1-pyrrolidinyl)ethyl ester, oxalate (1:1)
3209-74-3