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2-Hydroxy-2-phenylacetamidine

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Identification
Molecular formula
C8H10N2O
CAS number
.120419-11-6
IUPAC name
2-hydroxy-2-phenyl-acetamidine
State
State

At room temperature, 2-Hydroxy-2-phenylacetamidine is a solid. It is typically handled as a crystalline powder and should be stored in a tightly sealed container to prevent any moisture absorption.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
150.19g/mol
Molar mass
150.1880g/mol
Density
1.1000g/cm3
Appearence

2-Hydroxy-2-phenylacetamidine is typically a white to off-white crystalline solid. The compound's appearance may vary slightly depending on its purity and form.

Comment on solubility

Solubility of 2-hydroxy-2-phenyl-acetamidine

2-hydroxy-2-phenyl-acetamidine, known for its unique structural features, exhibits intriguing solubility characteristics:

  • Polar Nature: The presence of the hydroxy group (-OH) suggests that 2-hydroxy-2-phenyl-acetamidine is likely to have polar properties, which can enhance its solubility in polar solvents like water.
  • Hydrogen Bonding: This compound can form hydrogen bonds, which not only contributes to its stability but also promotes its interaction with solvents that can engage in hydrogen bonding.
  • Solvent Variability: Generally, such compounds are more soluble in water than in non-polar solvents due to their polar characteristics, but specific solubility can vary based on temperature and pH conditions.
  • Practical Implications: The solubility of 2-hydroxy-2-phenyl-acetamidine in biological and medicinal settings is significant, as it may influence the compound's bioavailability and efficacy.

In summary, while 2-hydroxy-2-phenyl-acetamidine's solubility can be anticipated based on its functional groups, experimental data is crucial for definitive understanding. Exploring further could reveal specific solubility limits in various solvents under different conditions.

Interesting facts

Interesting Facts about 2-Hydroxy-2-phenyl-acetamidine

2-Hydroxy-2-phenyl-acetamidine is an intriguing compound that presents a fascinating intersection of organic chemistry and medicinal applications. Here are some points that make this compound stand out:

  • Structure and Function: The unique structure of 2-hydroxy-2-phenyl-acetamidine includes a hydroxyl group and an amidine functional group, which can significantly influence its reactivity and interaction with biological targets.
  • Biological Relevance: This compound possesses potential pharmacological properties. Compounds containing the amidine structure are often investigated for their role as enzyme inhibitors, making them crucial in drug development for various diseases.
  • Versatility: The hydroxyl group in the compound can lead to a variety of derivative compounds through chemical modifications, providing numerous opportunities for researchers to explore its derivatives' different properties and applications.
  • Synthesis: The synthesis of 2-hydroxy-2-phenyl-acetamidine usually involves the reaction of an acetamidine with phenolic compounds, showcasing an interesting method for creating compounds with tailored characteristics for specific applications.
  • Research Implications: Research indicates that compounds like 2-hydroxy-2-phenyl-acetamidine could contribute to advancements in the fields of biochemistry and pharmacology, particularly in the design of novel therapeutic agents.

Given these points, it is clear that 2-hydroxy-2-phenyl-acetamidine is more than just a name; it is a compound with the potential to impact various scientific fields. The ongoing exploration of its properties and applications underscores the dynamic nature of chemical research.

Synonyms
2-hydroxy-2-phenylethanimidamide
51936-80-2
2-Hydroxy-2-phenylacetimidamide
mandelamidine
2-hydroxy-2-phenylethanamidine
Benzyl alcohol, alpha-amidino-
2-hydroxy-2-phenyl-acetamidine
SCHEMBL1623400
NIOSH/DN3153000
acetamidine, 2-hydroxy-2-phenyl-
SBB018894
SU-347
AKOS006283228
Ethanol, 2-amino-2-imino-1-phenyl-
benzene, (C-amidino-C-hydroxy)methyl-
DN31530000