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Acetophenone oxime hydrochloride

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Identification
Molecular formula
C8H10ClNO
CAS number
22699-21-4
IUPAC name
(2-hydroxy-2-phenyl-ethanimidoyl)ammonium;chloride
State
State

At room temperature, acetophenone oxime hydrochloride is in a solid state, appearing as a fine crystalline powder. It is stable under normal conditions but should be stored in a dry environment to prevent moisture absorption.

Melting point (Celsius)
233.50
Melting point (Kelvin)
506.65
Boiling point (Celsius)
257.20
Boiling point (Kelvin)
530.35
General information
Molecular weight
183.63g/mol
Molar mass
183.6300g/mol
Density
1.2123g/cm3
Appearence

Acetophenone oxime hydrochloride appears as a white to off-white crystalline powder. It is known for its fine powdery texture and is hygroscopic, absorbing moisture from the air, which can lead to clumping.

Comment on solubility

Solubility of (2-hydroxy-2-phenyl-ethanimidoyl)ammonium chloride

The solubility of (2-hydroxy-2-phenyl-ethanimidoyl)ammonium chloride in various solvents can significantly influence its applications in chemical synthesis and pharmaceutical research. While specific data on this compound might be sparse, we can generalize its solubility behavior based on structural characteristics.

  • Water Solubility: Due to the presence of the ammonium group, this compound is likely to exhibit moderate to high solubility in water. Ammonium salts tend to dissolve well in polar solvents because of their ionic nature.

  • Organic Solvent Solubility: The phenyl group introduces some hydrophobic characteristics, which may enhance solubility in polar organic solvents but could limit solubility in non-polar solvents.

  • Temperature Effects: Solubility can be influenced by temperature; typically, increased temperature leads to greater solubility for solids.

It's essential to conduct empirical solubility tests to accurately gauge the behavior of (2-hydroxy-2-phenyl-ethanimidoyl)ammonium chloride in various media, as solubility can vary widely depending on factors like concentration, pH, and interactions with other solutes.

Interesting facts

Interesting Facts about (2-hydroxy-2-phenyl-ethanimidoyl)ammonium Chloride

(2-hydroxy-2-phenyl-ethanimidoyl)ammonium chloride is a fascinating compound that showcases the intricate interplay between organic and inorganic chemistry. This compound, often referred to in the literature for its unique structural properties, has attracted attention for several reasons:

  • Versatile Applications: The compound is commonly utilized in synthetic organic chemistry as a versatile building block, particularly in the synthesis of various pharmaceuticals and organic compounds.
  • Hydrogen Bonding: The presence of a hydroxyl group in its structure significantly enhances its ability to undergo hydrogen bonding, which can influence its reactivity and interaction with other chemical species.
  • Chirality and Stereoisomerism: Being chiral, (2-hydroxy-2-phenyl-ethanimidoyl)ammonium chloride can exist in different stereoisomeric forms, each potentially exhibiting different biological activities or chemical reactivities.
  • Biological Significance: Some of the derivatives of this compound have been investigated for their anti-inflammatory and analgesic properties, making them of interest in medicinal chemistry and drug development.

Moreover, the compound's salts, particularly chlorides, often play a vital role in various chemical reactions administered in acidic conditions. As a student of chemistry might say, “Understanding the behavior of such compounds is crucial for mastering organic synthesis.”

Research on (2-hydroxy-2-phenyl-ethanimidoyl)ammonium chloride continues to enhance our understanding of complex chemical systems and paved the way for innovations in material science and pharmaceuticals.