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Phenylephrine Hydrochloride

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Identification
Molecular formula
C9H13NO2 · HCl
CAS number
61-76-7
IUPAC name
(2-hydroxy-2-phenyl-ethyl)-methyl-ammonium;chloride
State
State

Phenylephrine Hydrochloride is commonly found in a solid state as a crystalline powder at room temperature.

Melting point (Celsius)
137.00
Melting point (Kelvin)
410.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
203.66g/mol
Molar mass
203.6630g/mol
Density
1.0000g/cm3
Appearence

Phenylephrine Hydrochloride appears as a white to almost white crystalline powder. It is soluble in water and slightly soluble in alcohol.

Comment on solubility

Solubility of (2-hydroxy-2-phenyl-ethyl)-methyl-ammonium chloride

The solubility of (2-hydroxy-2-phenyl-ethyl)-methyl-ammonium chloride can be characterized by various factors, including its ionic nature, temperature, and the solvent used. As a quaternary ammonium compound, it generally demonstrates a tendency to be soluble in polar solvents, particularly water.

Factors Influencing Solubility

  • Ionic interactions: The presence of the chloride ion contributes to the compound's ability to dissolve in aqueous solutions.
  • Temperature: Increasing the temperature typically enhances solubility in many cases, allowing the compound to disperse more readily in solution.
  • Alternative solvents: While soluble in water, the compound may exhibit varying degrees of solubility in organic solvents, rendering it versatile for different applications.

Overall, it is often noted that (2-hydroxy-2-phenyl-ethyl)-methyl-ammonium chloride has a favorable solubility profile in aqueous environments, making it suitable for various biochemical applications. However, as solubility can be context-dependent, it is recommended to conduct empirical tests for specific solvent systems to confirm solubility properties.

Interesting facts

Interesting Facts about (2-hydroxy-2-phenyl-ethyl)-methyl-ammonium chloride

(2-hydroxy-2-phenyl-ethyl)-methyl-ammonium chloride, often referred to in academic discussions as a quaternary ammonium compound, presents significant potential in various fields, ranging from medicinal chemistry to materials science. Here are some fascinating insights:

  • Dual Character: This compound exhibits both hydroxyl (-OH) and quaternary ammonium functionalities, making it a robust candidate for numerous chemical reactions and applications.
  • Biological Relevance: Quaternary ammonium compounds are often characterized by their antimicrobial properties, meaning they can be utilized in disinfectants and antimicrobial agents.
  • Stability: The presence of the phenyl group enhances the molecule's stability, which is essential in drug formulation and delivery systems.
  • Applications in Drug Design: This compound structure can be a vital part of drug design, providing a framework for synthesizing new therapeutic agents.
  • Chemical Versatility: The hydroxyl group contributes to its ability to participate in hydrogen bonding, potentially increasing solubility in various solvents and enhancing its chemical versatility.

Interestingly, the study of such ammonium salts not only sheds light on fundamental chemistry concepts but also encourages innovation in material design and medicinal applications. As noted by chemist John C. Warner, "The best science often stems from creatively applying traditional concepts to solve modern problems." This encapsulates the potential of compounds like (2-hydroxy-2-phenyl-ethyl)-methyl-ammonium chloride in paving the way for future advancements in both chemistry and biochemistry.


Synonyms
61217-79-6
Benzyl alcohol, alpha-((methylamino)methyl)-, hydrochloride
(2-hydroxy-2-phenylethyl)-methylazanium;chloride
(2-hydroxy-2-phenylethyl)(methyl)azanium chloride
NSC 23619
Phenylethanolmethylamine, hydrochloride
1-Phenyl-2-methylaminoethanol hydrochloride
HALOSTACHINE, HYDROCHLORIDE, (+-)-
Phenyl(methylaminomethyl)carbinol, hydrochloride
alpha-Methylaminomethylbenzyl alcohol hydrochloride
Phenyl-beta-hydroxy-ethyl-methylamine, hydrochloride
l-1-Hydroxy-1-phenyl-2-methylaminoethane, hydrochloride
l-alpha-(Methylaminomethyl)benzyl alcohol, hydrochloride
BENZYL ALCOHOL, alpha-METHYLAMINOMETHYL-, HYDROCHLORIDE
(2-HYDROXY-2-PHENYL-ETHYL)-METHYL-AZANIUM CHLORIDE
Benzenemethanol, alpha-((methylamino)methyl)-, hydrochloride
DB-246841