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Phenylephrine hydrochloride

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Identification
Molecular formula
C8H11NO2·HCl
CAS number
61-76-7
IUPAC name
(2-hydroxy-2-phenyl-ethyl)ammonium;chloride
State
State

At room temperature, phenylephrine hydrochloride exists as a solid. It is typically distributed in powder form for medicinal uses, particularly in decongestants.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.00
Boiling point (Celsius)
80.00
Boiling point (Kelvin)
353.00
General information
Molecular weight
203.67g/mol
Molar mass
203.6740g/mol
Density
1.0500g/cm3
Appearence

Phenylephrine hydrochloride appears as a white or almost white crystalline powder. It is often used in the form of its hydrochloride salt due to enhanced solubility and stability.

Comment on solubility

Solubility of (2-hydroxy-2-phenyl-ethyl)ammonium chloride

(2-hydroxy-2-phenyl-ethyl)ammonium chloride is an interesting compound when it comes to its solubility characteristics. Understanding the solubility of this compound involves considering several factors:

  • Polarity: The presence of the hydroxyl (-OH) group contributes to the overall polarity of the molecule, which can enhance solubility in polar solvents like water.
  • Ionic Nature: As a chloride salt, the ionic component can further increase solubility in polar solvents and potentially facilitate dissolution due to ion-dipole interactions.
  • Temperature Dependence: Like many salts, the solubility may increase with temperature, making it more effective to dissolve in warm water.
  • pH Influence: The compound's solubility can be influenced by the pH of the solution, given that the ammonium part can accept protons under certain conditions, affecting its ionic state.

Overall, the solubility of (2-hydroxy-2-phenyl-ethyl)ammonium chloride is generally good in polar solvents, particularly in water, due to its structural features. As a compound of interest, it presents potential for various applications largely dictated by its solubility behavior.


Interesting facts

Interesting Facts about (2-hydroxy-2-phenyl-ethyl)ammonium chloride

(2-hydroxy-2-phenyl-ethyl)ammonium chloride, also known as a quaternary ammonium compound, exhibits a range of fascinating properties and applications that highlight its significance in both chemical research and practical uses. Here are some noteworthy aspects of this compound:

  • Amphiphilic Nature: This compound possesses both hydrophilic and hydrophobic characteristics, making it valuable in applications such as emulsifiers and surfactants.
  • Biological Activity: Quaternary ammonium compounds have been extensively studied for their antibacterial and antifungal properties. Research indicates that they may be effective against various pathogens.
  • Solvent for Reactions: Due to its unique structure, (2-hydroxy-2-phenyl-ethyl)ammonium chloride can serve as a solvent or stabilizing agent in various organic synthesis reactions.
  • Pharmaceutical Applications: This compound is of interest in drug design and formulation, particularly in enhancing the solubility or bioavailability of pharmaceutical agents.
  • Cross-Linking Agent: It has potential use as a cross-linking agent in polymer chemistry, contributing to the production of hydrogels and other materials with specific properties.
  • Sustainability: There is growing interest in the development of eco-friendly alternatives in chemical synthesis. Compounds like (2-hydroxy-2-phenyl-ethyl)ammonium chloride can be part of greener methodologies due to their versatility.

Overall, the study of (2-hydroxy-2-phenyl-ethyl)ammonium chloride not only contributes to our understanding of molecular behavior and interactions but also opens doors to innovative applications in various scientific fields. As a quote from a renowned chemist emphasizes, “Understanding the structures of compounds can lead to unparalleled advancements in science.” This compound exemplifies that principle through its diverse utility.

Synonyms
alpha-Phenyl-beta-aminoethanol hydrochloride
(2-hydroxy-2-phenylethyl)azanium;chloride
Phenylethanol amine hydrochloride
1-Ethanol, 1-phenyl-2-amino-, hydrochloride
Ethanol, alpha-phenyl-beta-amino-, hydrochloride
Benzenemethanol, alpha-(aminomethyl)-, hydrochloride
BENZYL ALCOHOL, alpha-(AMINOMETHYL)-, HYDROCHLORIDE