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Iodoxanol

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Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
2-hydroxy-3-[1-(3-iodophenyl)-3-oxo-butyl]chromen-4-one
State
State

At room temperature, Iodoxanol is typically in a solid state.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
750.00
Boiling point (Kelvin)
1 023.15
General information
Molecular weight
821.13g/mol
Molar mass
821.1270g/mol
Density
1.7600g/cm3
Appearence

Iodoxanol appears as a white to off-white crystalline powder. It is known for being a nonionic, dimeric, iodinated radiocontrast agent commonly used for medical imaging.

Comment on solubility

Solubility of 2-hydroxy-3-[1-(3-iodophenyl)-3-oxo-butyl]chromen-4-one

The solubility of the compound 2-hydroxy-3-[1-(3-iodophenyl)-3-oxo-butyl]chromen-4-one can be influenced by several factors due to its complex structure. Here are some key considerations regarding its solubility:

  • Polarity: The presence of hydroxyl groups makes the molecule somewhat polar, which generally enhances its solubility in polar solvents such as water and alcohols.
  • Aromatic Influence: The aromatic ring within the structure may lead to increased solubility in organic solvents, particularly non-polar ones like benzene or hexane.
  • Hydrogen Bonding: The -OH group can participate in hydrogen bonding, which may significantly influence solubility behavior in various solvents.
  • Temperature Effect: As with many compounds, solubility can be temperature-dependent. Higher temperatures can enhance solubility by providing sufficient energy to overcome intermolecular forces.

It is important to note that specific data regarding exact solubility values may vary, and experimental determination in relevant solvents might yield more definitive insights. Additionally, factors like pH and the presence of other ions in solution can further affect the solubility of this compound.

In summary, while the unique characteristics of 2-hydroxy-3-[1-(3-iodophenyl)-3-oxo-butyl]chromen-4-one promote varied solubility properties, understanding the interplay between its functional groups, solvent choice, and environmental conditions is crucial for predicting its behavior in solution.

Interesting facts

Interesting Facts about 2-Hydroxy-3-[1-(3-Iodophenyl)-3-Oxo-Butyl]Chromen-4-One

The compound known as 2-hydroxy-3-[1-(3-iodophenyl)-3-oxo-butyl]chromen-4-one is a fascinating molecule in the realm of organic chemistry. Here are some interesting points that highlight its significance:

  • Chromone Backbone: This compound features a chromone structure, a prominent moiety in many biologically active natural products.
  • Iodine Substituent: The presence of the iodine atom not only contributes to its unique properties but also enhances its potential in medicinal chemistry, as iodine is known to increase the lipophilicity of organic molecules.
  • Pharmacological Potential: Compounds similar to this one have been studied for their anti-inflammatory, antioxidant, and anticancer activities. The unique substitution pattern could lead to new therapeutic applications.
  • Synthesis Challenges: The synthesis of such complex molecules can present significant challenges, often requiring multi-step procedures and careful control of reaction conditions.
  • Research Importance: This compound serves as a valuable point of study in chemical research, particularly in examining the structure-activity relationship (SAR) of chromone derivatives.

As the field of medicinal chemistry continues to evolve, compounds like 2-hydroxy-3-[1-(3-iodophenyl)-3-oxo-butyl]chromen-4-one are pivotal for driving advancements in drug discovery and development. Understanding their intricate structures allows chemists to innovate and synthesize novel compounds for therapeutic use.