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Naringenin

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Identification
Molecular formula
C15H12O3
CAS number
480-41-1
IUPAC name
2-hydroxy-3-(1-phenylpropyl)chromen-4-one
State
State

Naringenin is in a solid state at room temperature.

Melting point (Celsius)
252.00
Melting point (Kelvin)
525.20
Boiling point (Celsius)
544.20
Boiling point (Kelvin)
817.30
General information
Molecular weight
272.26g/mol
Molar mass
272.2580g/mol
Density
1.3240g/cm3
Appearence

Naringenin is a flavanone compound that typically appears as a pale yellow solid.

Comment on solubility

Solubility of 2-hydroxy-3-(1-phenylpropyl)chromen-4-one

The solubility of 2-hydroxy-3-(1-phenylpropyl)chromen-4-one, a notable flavonoid compound, is influenced by various factors such as temperature, pH, and solvent type. Generally, flavonoids have varying solubility profiles:

  • Polar Solvents: This compound tends to have greater solubility in polar solvents like water and alcohols due to the presence of the hydroxyl group.
  • Non-Polar Solvents: In contrast, solubility may decrease in non-polar solvents like hexane, as the compound may have limited interactions with these solvents.
  • pH Levels: The solubility can further vary with changes in pH; in acidic environments, the hydroxyl group may become protonated, affecting its ability to dissolve.

As a general guideline, it can be said that:

  1. "Increased temperature usually enhances solubility for many substances."
  2. "Compounds with multiple functional groups often exhibit better solubility."

In conclusion, understanding the solubility characteristics of 2-hydroxy-3-(1-phenylpropyl)chromen-4-one is crucial for its applications in various fields, including pharmaceuticals and natural products chemistry.

Interesting facts

Interesting Facts about 2-hydroxy-3-(1-phenylpropyl)chromen-4-one

2-hydroxy-3-(1-phenylpropyl)chromen-4-one, commonly known as a flavonoid, represents a fascinating class of compounds with a wide array of activities and applications. These compounds are characterized by their structure, which includes:

  • Flavonoid Backbone: This compound features a chromone structure, which is integral to its function.
  • Hydroxyl Group: The presence of the hydroxyl (-OH) group contributes to its solubility and reactivity, enhancing its biological interactions.
  • Phenyl Propyl Side Chain: The addition of a phenylpropyl group adds to the compound's potential biological activity and can affect its binding properties.

This compound has gained attention in the field of medicinal chemistry due to its potential therapeutic applications, which include:

  • Antioxidant Activity: Like many flavonoids, it may help combat oxidative stress in biological systems.
  • Anti-inflammatory Properties: Research suggests it could reduce inflammation, making it a candidate for treating chronic inflammatory conditions.
  • Anticancer Potential: Some studies indicate that compounds with similar structures have shown promise in inhibiting cancer cell proliferation.

Additionally, this compound can often be found in plant sources, contributing to their health benefits, and is studied for its role in traditional medicine as well as its potential in drug development. Fascinatingly, flavonoids like this one also play a role in providing color to plants and fruits, contributing to their attractiveness, and thereby aiding in pollination.

Key Takeaways:

  • We are only beginning to unlock the full scope of biological activities of this flavonoid.
  • Continued research may lead to novel applications in pharmaceuticals and nutraceuticals.
  • Understanding its structure and function can give insights into the broader categories of flavonoids and their health benefits.