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Coumarin 6

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Identification
Molecular formula
C20H16O4
CAS number
38215-36-0
IUPAC name
2-hydroxy-3-[(2-hydroxy-1-naphthyl)methyl]chromen-4-one
State
State

At room temperature, Coumarin 6 is in a solid state, typically found as a powder.

Melting point (Celsius)
216.00
Melting point (Kelvin)
489.15
Boiling point (Celsius)
510.00
Boiling point (Kelvin)
783.15
General information
Molecular weight
350.39g/mol
Molar mass
350.3900g/mol
Density
1.2933g/cm3
Appearence

Coumarin 6 appears as a yellow crystalline powder.

Comment on solubility

Solubility of 2-hydroxy-3-[(2-hydroxy-1-naphthyl)methyl]chromen-4-one

The solubility of 2-hydroxy-3-[(2-hydroxy-1-naphthyl)methyl]chromen-4-one, also known as a derivative of flavonoids, presents intriguing characteristics influenced by its molecular structure.

Key factors affecting its solubility include:

  • Polarity: The presence of hydroxyl groups makes the compound relatively polar, which enhances its solubility in polar solvents such as water.
  • Hydrophobic regions: The naphthyl group contributes to hydrophobic interactions, which can affect solubility in non-polar solvents.
  • Temperature: Like many organic compounds, its solubility may vary significantly with temperature, generally increasing as the temperature rises.

Various studies indicate that flavonoids, particularly those with multiple hydroxyl substituents, are often soluble in organic solvents as well, including:

  • Alcohols (e.g., ethanol, methanol)
  • Acetone
  • Dimethyl sulfoxide (DMSO)

Thus, it can be concluded that while 2-hydroxy-3-[(2-hydroxy-1-naphthyl)methyl]chromen-4-one exhibits good solubility in polar solvents, its solubility profile in non-polar media might be limited due to the competing polar and non-polar functional groups within its structure. This dual nature can make it a fascinating subject for further study in medicinal and chemical applications.

Interesting facts

Interesting Facts about 2-hydroxy-3-[(2-hydroxy-1-naphthyl)methyl]chromen-4-one

2-hydroxy-3-[(2-hydroxy-1-naphthyl)methyl]chromen-4-one, commonly known as a derivative of flavonoids, is a fascinating compound that has garnered significant attention in the field of natural products and medicinal chemistry. Here are some key insights about this intriguing compound:

  • Flavonoid Family: This compound belongs to the flavonoid family, which is renowned for its diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties.
  • Natural Sources: It can be found in various plants, particularly those known for their medicinal uses in traditional systems of medicine like Ayurveda and Traditional Chinese Medicine.
  • Biological Activity: Research has shown that derivatives similar to this compound exhibit a range of biological activities. Some potential benefits include:
    • Modulation of cellular signaling pathways
    • Inhibition of tumor growth
    • Protection against oxidative stress
  • Research Potential: Scientists are continually exploring the pharmacological applications of this compound. Future studies may reveal its potential in developing therapeutic agents for various diseases.
  • Structure-Activity Relationship: The unique structure of 2-hydroxy-3-[(2-hydroxy-1-naphthyl)methyl]chromen-4-one allows for the exploration of how changes in its molecular structure can influence its activity. This makes it an excellent subject for theoretical and experimental studies.

In conclusion, 2-hydroxy-3-[(2-hydroxy-1-naphthyl)methyl]chromen-4-one is not just an ordinary flavonoid; its profound implications in health and disease invite exciting new research avenues. As a student or scientist, delving into its complexities can lead to remarkable insights into the world of organic compounds!