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Carbofuran

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Identification
Molecular formula
C12H15NO3
CAS number
1563-66-2
IUPAC name
[2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate
State
State

At room temperature, carbofuran is typically a solid. It is used as an insecticide and is known for its effectiveness in agriculture, though it's applied in a highly controlled manner due to its toxicity.

Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
221.20g/mol
Molar mass
221.2010g/mol
Density
1.1800g/cm3
Appearence

Carbofuran appears as a white crystalline solid. It is known for its high solubility in organic solvents and has a distinct chemical odor.

Comment on solubility

Solubility of [2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate

[2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate, with the chemical formula C12H15NO3, presents interesting solubility characteristics that are influenced by both its functional groups and molecular structure. Understanding its solubility can provide insight into its potential applications and behavior in various environments.

Key Aspects of Solubility

  • Polarity: The presence of a hydroxyl group (-OH) suggests that the compound may interact favorably with polar solvents, particularly water, which can enhance its solubility.
  • Hydrophobic Interactions: The methoxyphenyl group contributes to hydrophobic interactions, potentially limiting solubility in highly polar solvents.
  • Form of Carbamate: Carbamates are generally expected to exhibit moderate solubility in organic solvents, as well as variable solubility in water, depending on their structure.

Therefore, it can be anticipated that [2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate might demonstrate:

  1. Moderate solubility in water due to polar interactions.
  2. Increased solubility in organic solvents such as ethanol or acetone.
  3. Potential challenges in solubility under certain conditions due to competing hydrophobic properties.

In conclusion, while [2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate has favorable attributes for solubility in certain solvents, the overall solubility profile is context-dependent, influenced by both the solvent polarity and the intermolecular interactions at play.

Interesting facts

Interesting Facts About [2-Hydroxy-3-(2-methoxyphenoxy)propyl] Carbamate

[2-Hydroxy-3-(2-methoxyphenoxy)propyl] carbamate is an intriguing compound that showcases the versatility of carbamates in chemical applications. This compound can be analyzed from various perspectives including its synthesis, potential uses, and interactions within biological systems.

Synthesis and Structure

The synthesis of this compound typically involves the reaction of phenolic substances with carbamate precursors. The presence of the methoxyphenoxy group introduces unique reactivity patterns and enhances solubility in organic solvents. Such structural motifs are pivotal in creating libraries of compounds for pharmaceutical research.

Biological Potential

This compound's hydroxyl group plays a crucial role in its biological activity, possibly contributing to its ability to interact with various biological targets. Some interesting aspects include:

  • Enzyme Inhibition: Compounds like this one can serve as inhibitors for certain enzymes, potentially leading to therapeutic applications.
  • Drug Design: The presence of functional groups allows for modifications that can enhance efficacy and reduce side effects.
  • Target Interaction: The unique structure may lead to selective interactions with receptors or enzymes, making it a candidate for targeted drug development.

Applications

In terms of practical applications, [2-Hydroxy-3-(2-methoxyphenoxy)propyl] carbamate is being studied for its potential roles in:

  • Pesticide Formulations: The compound may be explored as an active ingredient in protecting crops.
  • Pharmaceutical Chemistry: Its structure may inspire new candidates for treating diseases.

Research and Future Directions

As scientific research continues to evolve, the role of such compounds becomes increasingly important. With advancements in organic synthesis and understanding of structure-activity relationships, we can anticipate innovative applications on the horizon.

In conclusion, [2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate is more than just a chemical compound; it represents the intersection of synthetic chemistry and biological sciences, promising exciting discoveries in future research.

Synonyms
methocarbamol
532-03-6
Robaxin
Delaxin
Metocarbamol
Metocarbamolo
Etroflex
Lumirelax
Methocal
Metofenia
Miolaxene
Miorilas
Myolaxene
Parabaxin
Reflexyn
Relestrid
Romethocarb
Surquetil
Tresortil
Avetil
Miowas
Perilax
Robinax
Forbaxin
Metofenina
Neuraxin
Guaiphenesin carbamate
Guaiacol glyceryl ether carbamate
2-Hydroxy-3-(2-methoxyphenoxy)propyl carbamate
Guaiphenesine carbamate
Glycerylguaiacolate carbamate
Glycerylguajacol-carbamat
AHR 85
Methocarbamolum
Robaxine
Robamol
Robaxan
Robaxon
1,2-Propanediol, 3-(2-methoxyphenoxy)-, 1-carbamate
Guiacol-gliceriletere monocarbammato
3-(o-Methoxyphenoxy)-2-hydroxypropyl carbamate
ROBAXIN-750
3-(2-Methoxyphenoxy)-1-glyceryl carbamate
NSC 170960
HSDB 3122
2-Hydroxy-3-(o-methoxyphenoxy)propyl 1-carbamate
[2-hydroxy-3-(2-methoxyphenoxy)propyl] carbamate
3-(o-Methoxyphenoxy)-1,2-propanediol 1-carbamate
EINECS 208-524-3
Metocarbamol [INN-Spanish]
MFCD00057662
Methocarbamolum [INN-Latin]
NSC-170960
BRN 1884446
DTXSID6023286
UNII-125OD7737X
1,2-Propanediol, 3-(o-methoxyphenoxy)-, 1-carbamate
Carbamic acid, 2-hydroxy-3-(o-methoxyphenoxy)propyl ester
125OD7737X
MLS000028610
DTXCID503286
CHEBI:77498
Methocarbamol [USP:INN:BAN:JAN]
3-(2-Methoxyphenoxy)-1,2-propanediol 1-carbamate
NSC170960
ROBAXISAL COMPONENT METHOCARBAMOL
(+-)-3-(o-Methoxyphenoxy)-1,2-propanediol 1-carbamate
SMR000058719
Traumacut
Metocarbamol (INN-Spanish)
Methocarbamolum (INN-Latin)
METHOCARBAMOL (MART.)
METHOCARBAMOL [MART.]
METHOCARBAMOL (USP-RS)
METHOCARBAMOL [USP-RS]
(RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
Metocarbamolo [DCIT]
Robaxisol
(+/-)-3-(O-METHOXYPHENOXY)-1,2-PROPANEDIOL 1-CARBAMATE
(R)-Methocarbamol
Methocarbamol (USP:INN:BAN:JAN)
METHOCARBAMOL (USP MONOGRAPH)
METHOCARBAMOL [USP MONOGRAPH]
1,2-PROPANEDIOL, 3-(2-METHOXYPHENOXY)-, 1-CARBAMATE, (+/-)-
Carbamate, Guaiphenesin
SR-01000000240
2-hydroxy-3-{[2-(methyloxy)phenyl]oxy}propyl carbamate
Robaxin-V Tablets
NCGC00016492-01
Methocarbamol,(S)
CAS-532-03-6
Prestwick_614
Delaxin (TN)
Robaxin (TN)
Methocarbamol Tablets
METHCARBAMOL
Robaxin-V Injectable
Methocarb 500-EZS
Robaxisol (Salt/Mix)
Spectrum_000997
Methocarbamol (Robaxin)
Methocarbamol (Standard)
Opera_ID_1471
Prestwick0_000184
Prestwick1_000184
Prestwick2_000184
Prestwick3_000184
Spectrum2_001272
Spectrum3_000496
Spectrum4_000049
Spectrum5_000956
METHOCARBAMOL [MI]
2-Hydroxy-3-(o-methoxyphenoxy)propyl carbamate
METHOCARBAMOL [INN]
METHOCARBAMOL [JAN]
METHOCARBAMOL [HSDB]
SCHEMBL34365
BSPBio_000107
BSPBio_001991
KBioGR_000517
KBioSS_001477
METHOCARBAMOL [VANDF]
MLS001148605
DivK1c_000434
SPECTRUM1500397
WLN: ZVO1YQ1OR BO1
SPBio_001264
SPBio_002028
METHOCARBAMOL [WHO-DD]
BPBio1_000119
CHEBI:6832
GTPL6829
Methocarbamol (JAN/USP/INN)
Methocarbamol Granules DC 90%
CHEMBL1201117
HMS501F16
HY-B0262R
KBio1_000434
KBio2_001477
KBio2_004045
KBio2_006613
KBio3_001491
M03BA03
NINDS_000434
HMS1568F09
HMS1920L19
HMS2091D14
HMS2095F09
HMS2233G18
HMS3259M17
HMS3369B17
HMS3655O06
HMS3712F09
METHOCARBAMOL [GREEN BOOK]
Pharmakon1600-01500397
METHOCARBAMOL [ORANGE BOOK]
145841-69-6
BCP13801
HY-B0262
Tox21_110454
CCG-39655
NSC757112
s1736
Methocarbamol Tablets, USP, 500 mg
Methocarbamol Tablets, USP, 750 mg
AKOS015960743
Tox21_110454_1
DB00423
FM25163
NC00509
NSC-757112
IDI1_000434
NCGC00018257-02
NCGC00018257-03
NCGC00018257-04
NCGC00018257-07
NCGC00018257-08
NCGC00018257-16
NCGC00089805-02
NCGC00089805-03
1, 3-(o-methoxyphenoxy)-, 1-carbamate
AC-12037
AS-11691
DA-65368
SY035642
1, 3-(2-methoxyphenoxy)-, 1-carbamate
METHOCARBAMOL COMPONENT OF ROBAXISAL
SBI-0051442.P003
3-O-(2-Methoxyphenyl)-1-glyceryl carbamate
AB00052040
M2254
NS00001031
SW196781-3
D00402
D70323
EN300-119525
AB00052040-15
AB00052040_16
AB00052040_17
2-Hydroxy-3-(2-methoxyphenoxy)propyl carbamate #
Q411456
rac-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
SR-01000000240-2
SR-01000000240-3
(+-)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
BRD-A31521121-001-05-8
BRD-A31521121-001-25-6
BRD-A31521121-001-26-4
Guaiacol glyceryl ether carbamate, analytical standard
Z1521553984
Carbamic Acid 2-Hydroxy-3-(2-methoxyphenoxy)propyl Ester
carbamic acid [2-hydroxy-3-(2-methoxy-phenoxy)-propyl] ester
Methocarbamol, United States Pharmacopeia (USP) Reference Standard
Methocarbamol, Pharmaceutical Secondary Standard; Certified Reference Material
208-524-3
3967-43-9