Skip to main content

Carvedilol

ADVERTISEMENT
Identification
Molecular formula
C24H26FNO4
CAS number
72956-09-3
IUPAC name
[2-hydroxy-3-(2-methylphenoxy)propyl] 2-(4-fluorophenoxy)acetate
State
State

At room temperature, Carvedilol is in a solid state.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.00
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.00
General information
Molecular weight
406.49g/mol
Molar mass
406.4860g/mol
Density
1.2000g/cm3
Appearence

Carvedilol appears as a white to off-white crystalline powder. It is sparingly soluble in methanol, slightly soluble in ethanol, and practically insoluble in water.

Comment on solubility

Solubility of [2-hydroxy-3-(2-methylphenoxy)propyl] 2-(4-fluorophenoxy)acetate

The solubility of the compound [2-hydroxy-3-(2-methylphenoxy)propyl] 2-(4-fluorophenoxy)acetate can be influenced by various factors, including its molecular structure and the presence of polar or non-polar functional groups. This compound features both aromatic and hydroxy groups, which play a crucial role in determining its solubility in different solvents. Here are some key points on its solubility characteristics:

  • Polarity: The hydroxy group in the molecule may enhance its solubility in polar solvents, such as water or methanol, due to hydrogen bonding.
  • Aromatic Interactions: The presence of aromatic moieties can lead to greater solubility in organic solvents like ethanol, acetone, or dichloromethane.
  • Hydrophobic Regions: On the other hand, the compound's bulky aromatic structures could hinder solvation, potentially reducing solubility in highly polar solvents.
  • Temperature Influence: Solubility may also depend on temperature, with increased temperatures generally leading to enhanced solubility for many compounds.

In conclusion, predicting the exact solubility of [2-hydroxy-3-(2-methylphenoxy)propyl] 2-(4-fluorophenoxy)acetate would require empirical data, considering both the functional groups and the solvent characteristics. Experimental determination in various solvents remains the most reliable method for understanding its solubility behavior.

Interesting facts

Interesting Facts About [2-hydroxy-3-(2-methylphenoxy)propyl] 2-(4-fluorophenoxy)acetate

[2-hydroxy-3-(2-methylphenoxy)propyl] 2-(4-fluorophenoxy)acetate, a fascinating compound, showcases the intricate interplay between functional groups in organic chemistry. Here are some noteworthy aspects:

  • Versatile Functional Groups: The compound features a combination of hydroxyl, ether, and ester groups, which contribute to its chemical reactivity and potential applications in various fields.
  • Biological Significance: Compounds with similar structure have been studied for their biological activity, making them of interest in pharmaceutical research and development.
  • Fluorine Impact: The presence of fluorine in the molecule can significantly affect its biological properties. Fluorinated compounds often exhibit increased metabolic stability and altered lipophilicity, enhancing their potential as drug candidates.
  • Structure-Activity Relationship (SAR): Understanding how the arrangement of the 2-methylphenoxy and 4-fluorophenoxy moieties influences the biological activity can guide modifications in drug design and optimization.

As a student of chemistry, you might appreciate how the specific arrangement of atoms within this compound allows it to engage in various interactions, potentially making it useful in targeted therapies or as a lead compound in medicinal chemistry. Furthermore, the ability to synthesize and manipulate such compounds highlights the innovative nature of modern chemistry.


In summary, the exploration of [2-hydroxy-3-(2-methylphenoxy)propyl] 2-(4-fluorophenoxy)acetate opens doors to understanding complex chemical behavior and its applications in scientific advancements. The blend of different functional groups emphasizes the beauty and complexity of organic compounds.

Synonyms
17753-07-0
[2-hydroxy-3-(2-methylphenoxy)propyl] 2-(4-fluorophenoxy)acetate
p-Fluorophenoxyacetic acid 2-hydroxy-3-(o-tolyloxy)propyl ester
(p-Fluorophenoxy)acetic acid 2-hydroxy-3-(o-tolyloxy)propyl ester
ACETIC ACID, (p-FLUOROPHENOXY)-, 2-HYDROXY-3-(o-TOLYLOXY)PROPYL ESTER
DTXSID80938958
2-hydroxy-3-(2-methylphenoxy)propyl (4-fluorophenoxy)acetate
[2-Hydroxy-3-(2-methylphenoxy)propyl]2-(4-fluorophenoxy)acetate