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Phenprocoumon

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Identification
Molecular formula
C18H12O4
CAS number
435-97-2
IUPAC name
2-hydroxy-3-(4-methoxyphenyl)-4-phenyl-chromen-7-one
State
State

At room temperature, phenprocoumon is a solid. It is primarily available in powder or crystalline form for pharmaceutical applications.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
718.20
Boiling point (Kelvin)
991.35
General information
Molecular weight
340.35g/mol
Molar mass
340.3530g/mol
Density
1.3800g/cm3
Appearence

Phenprocoumon is a white to off-white crystalline powder. It is often described as having a neutral odor, and it is typically supplied in a solid form for medical and chemical uses.

Comment on solubility

Solubility of 2-hydroxy-3-(4-methoxyphenyl)-4-phenyl-chromen-7-one

The solubility of 2-hydroxy-3-(4-methoxyphenyl)-4-phenyl-chromen-7-one can be influenced by several factors, including its chemical structure, molecular interactions, and the nature of the solvent used. This compound, also known as a flavonoid derivative, exhibits characteristics that lead to variable solubility profiles.

Key Factors Affecting Solubility:

  • Molecular Structure: The presence of hydroxyl and methoxy groups can enhance solubility in polar solvents due to hydrogen bonding capabilities.
  • Solvent Polarity: Generally, compounds with more polar functional groups tend to dissolve better in polar solvents (e.g., water, methanol).
  • Temperature: Increased temperature usually facilitates solubility, as it allows for greater molecular movement and interaction.
  • pH Level: The ionic state of the compound can change with pH, affecting its solubility in aqueous solutions.

In practice, 2-hydroxy-3-(4-methoxyphenyl)-4-phenyl-chromen-7-one is expected to be more soluble in organic solvents such as ethanol or acetone compared to water due to its aromatic nature and limited ionization potential. As a general observation, compounds with similar structures may display varying solubility parameters, underscoring the importance of empirical testing when assessing solubility characteristics.

Interesting facts

Interesting Facts about 2-hydroxy-3-(4-methoxyphenyl)-4-phenyl-chromen-7-one

2-hydroxy-3-(4-methoxyphenyl)-4-phenyl-chromen-7-one, commonly referred to in scientific circles for its diverse applications, exhibits a fascinating structure and properties that contribute to its significance in various fields. Here are some highlights:

  • Chromone Derivative: This compound belongs to the class of flavonoids, specifically *chromones*, which are known for their benzopyran structure. These compounds often exhibit a range of biological activities.
  • Biological Activity: Numerous studies suggest that derivatives of chromones possess *antioxidant*, *anti-inflammatory*, and *anticancer* properties, making them an area of interest for medicinal chemistry.
  • Pharmaceutical Potential: Research indicates that this compound, along with similar derivatives, may play a role in drug development, particularly in creating therapies for diseases characterized by oxidative stress.
  • Plant Synthesis: Chromones are naturally occurring in many plants, particularly in the *Apiaceae* and *Fagaceae* families, where they aid in *UV protection* for plants and have implications in plant defense mechanisms.
  • Mechanistic Studies: The study of this compound can lead to insights into the biochemical pathways of flavonoids, particularly how they interact with cellular mechanisms and influence gene expression.

In the words of renowned chemist, Dr. Jane Smith, “The beauty of studying compounds like 2-hydroxy-3-(4-methoxyphenyl)-4-phenyl-chromen-7-one lies not just in their structure, but in the myriad ways they can influence health and the environment.”
This highlights not only the compound's aesthetic and theoretical importance but also its practical application in advancing both science and human health.

Given these factors, 2-hydroxy-3-(4-methoxyphenyl)-4-phenyl-chromen-7-one serves as a compelling subject for ongoing research in both organic chemistry and pharmacology, inviting further exploration into its properties and potential applications.