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Propranolol hydrochloride

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Identification
Molecular formula
C16H22ClNO2
CAS number
318-98-9
IUPAC name
[2-hydroxy-3-[4-(propylamino)benzoyl]oxy-propyl]-dimethyl-ammonium;chloride
State
State
At room temperature, propranolol hydrochloride exists as a solid. It is usually provided in the form of tablets or capsules for medicinal use.
Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
197.00
Boiling point (Kelvin)
470.15
General information
Molecular weight
295.81g/mol
Molar mass
295.8110g/mol
Density
1.2000g/cm3
Appearence

Propranolol hydrochloride typically appears as a white to off-white crystalline powder when in its pure form. It is odorless and has a bitter taste.

Comment on solubility

Solubility Characteristics of [2-hydroxy-3-[4-(propylamino)benzoyl]oxy-propyl]-dimethyl-ammonium;chloride

The solubility of [2-hydroxy-3-[4-(propylamino)benzoyl]oxy-propyl]-dimethyl-ammonium;chloride is influenced by several factors, particularly its ionic and polar nature due to the presence of the quaternary ammonium group and the chloride ion. Understanding its solubility involves various aspects:

  • Solvent Type: This compound tends to be soluble in polar solvents, especially water, due to its ionic character. The ammonium group can interact favorably with water molecules, enhancing solubility.
  • Temperature Influence: As with many compounds, increasing the temperature generally improves solubility. Higher temperatures can facilitate the dissolution process, allowing for greater molecular interaction.
  • Concentration Dependency: At lower concentrations, solubility can be higher, but as saturation occurs, the solubility may plateau.
  • pH Levels: The solubility may also vary with changes in pH, as the ionization state of the compound may be affected, leading to different solubility profiles in acidic or basic conditions.

In essence, the *solubility* of this compound plays a vital role in its application and effectiveness in various environments. As noted in studies, "*The solubility of quaternary ammonium compounds often dictates their efficacy in biological systems and industrial applications*". Hence, knowing these solubility characteristics is essential for optimizing its use.

Interesting facts

Interesting Facts about 2-hydroxy-3-[4-(propylamino)benzoyl]oxy-propyl]-dimethyl-ammonium;chloride

This compound, commonly known for its applications in various fields, represents the intersection of organic chemistry and pharmacology. Here are some intriguing aspects to consider:

  • Quaternary Ammonium Compound: As a quaternary ammonium compound, it demonstrates unique properties, including surfactant activity. This makes it useful in both industrial and biomedical settings.
  • Biological Significance: The presence of the propylamino group suggests potential interactions with biological systems, specifically in pharmaceuticals where such compounds can serve as drug delivery agents or as active pharmaceutical ingredients.
  • Stability and Activity: Its stability under various conditions makes it a valuable candidate for formulations that require shelf stability while retaining biological activity.
  • Research Potential: Ongoing studies explore its potential in targeted drug delivery systems, making it a compound of interest in the development of new therapeutic modalities.
  • Environmental Impact: As compounds of this nature can often be used in water treatment, understanding their environmental footprint is crucial for sustainable applications. They can help in the removal of contaminants while maintaining ecological balance.
  • Designing New Compounds: The architecture of this molecule highlights the importance of structural design in chemistry; modifications could lead to new compounds with enhanced efficacy or reduced side effects.

In conclusion, 2-hydroxy-3-[4-(propylamino)benzoyl]oxy-propyl]-dimethyl-ammonium;chloride embodies the creativity and innovation found in the realm of chemical synthesis. As scientists continue to explore its properties and applications, it not only contributes to our understanding of chemistry but also offers promising avenues for future research.

Synonyms
4172-63-8
3-(Dimethylamino)-2-hydroxypropyl p-(propylamino)benzoate hydrochloride
4-Propylamino-benzoesaeure-gamma-dimethylamino-beta-hydroxy-propylester hydrochloride
Benzoic acid, p-(propylamino)-, 3-(dimethylamino)-2-hydroxypropyl ester, hydrochloride