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Ibuprofen

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Identification
Molecular formula
C13H18O2
CAS number
15687-27-1
IUPAC name
2-hydroxy-3-isopropyl-6-methyl-benzoic acid
State
State

At room temperature, ibuprofen is typically a solid and is commonly distributed in the form of tablets, capsules, and powder.

Melting point (Celsius)
76.00
Melting point (Kelvin)
349.15
Boiling point (Celsius)
157.00
Boiling point (Kelvin)
430.15
General information
Molecular weight
206.29g/mol
Molar mass
206.2850g/mol
Density
1.0300g/cm3
Appearence

Ibuprofen typically appears as a white, powdery crystalline substance. It may also be found in various formulations such as tablets and suspension for pharmaceutical use. The crystals are fine and typically odorless.

Comment on solubility

Solubility of 2-Hydroxy-3-isopropyl-6-methyl-benzoic Acid

The solubility of 2-hydroxy-3-isopropyl-6-methyl-benzoic acid, commonly known as ibuprofen, varies with temperature and solvent. Generally, it is considered to be moderately soluble in water, especially when heated. Understanding its solubility characteristics is essential for pharmaceutical formulations and applications.

Factors Influencing Solubility:

  • Temperature: Solubility tends to increase with rising temperatures, which is crucial when dissolving the compound in liquid formulations.
  • pH of the solvent: Being a carboxylic acid, the solubility of ibuprofen can be affected by the pH levels; it tends to be more soluble in alkaline solutions.
  • Presence of co-solvents: The addition of organic solvents, like ethanol or propylene glycol, can enhance its solubility in aqueous solutions.

In conclusion, the solubility of 2-hydroxy-3-isopropyl-6-methyl-benzoic acid is influenced by various factors, and careful manipulation of these elements can optimize its use in diverse applications. As with all chemical compounds, it is vital to consider solubility when developing effective formulations.

Interesting facts

Interesting Facts about 2-Hydroxy-3-isopropyl-6-methyl-benzoic Acid

2-Hydroxy-3-isopropyl-6-methyl-benzoic acid, commonly known for its role in various chemical applications, is a fascinating compound with an array of interesting properties and uses. Here are several key points that highlight its significance:

  • Functional Groups: This compound features both a carboxylic acid group and a hydroxyl group, which is indicative of its acidic and alcohol characteristics respectively. Such functional groups play a crucial role in reactivity and interactions with other molecules.
  • Applications in Chemistry: This compound is often used in organic synthesis as a starting material for the manufacture of dyes, pharmaceuticals, and other complex organic molecules.
  • Biological Importance: Compounds similar to this one have been studied for their potential biological activity, including anti-inflammatory and antioxidant effects, making them of interest in medicinal chemistry.
  • Pesticide Research: The structural features of 2-hydroxy-3-isopropyl-6-methyl-benzoic acid enhance its appeal in pesticide formulation research, contributing to more effective agricultural practices.
  • Potential for Further Study: As a derivative of benzoic acid, it can serve as a basis for exploring novel compounds with diverse functionalities. The intricacies of its structure allow for modifications that might lead to new discoveries in both chemistry and materials science.

As a chemistry student or enthusiast, understanding the nuances of compounds like 2-hydroxy-3-isopropyl-6-methyl-benzoic acid enriches your knowledge of chemical reactions and industrial applications. “The beauty of chemistry lies not only in its complexity but also in its ability to innovate and improve our daily lives.”

In summary, 2-hydroxy-3-isopropyl-6-methyl-benzoic acid presents a captivating blend of chemical properties and applications, making it a prime subject for anyone keen on the vast field of chemistry.

Synonyms
2-Hydroxy-3-isopropyl-6-methylbenzoic acid
548-51-6
o-Thymotic acid
o-Thymotinic acid
o-Thymolcarboxylic acid
2-Thymotic acid
Orthothymotic acid
2-Thymolcarboxylic acid
3-Isopropyl-6-methylsalicylic acid
6-Methyl-3-isopropylsalicylic acid
3-Hydroxy-2-p-cymenecarboxylic acid
3-Isopropyl-6 methyl salicylic acid
2-Methyl-5-isopropylsalicyclic acid
EINECS 208-949-4
Benzoic acid, 2-hydroxy-6-methyl-3-(1-methylethyl)-
NSC 68360
3-Hydroxy-p-cymene-2-carboxylic acid
BRN 2578282
GF566F3K7L
2-Hydroxy-6-methyl-3-(1-methylethyl)benzoic acid
NSC-68360
NSC-76970
p-CYMENE-2-CARBOXYLIC ACID, 3-HYDROXY-
O-THYMOTIC ACID [MI]
DTXSID80203279
3-10-00-00629 (Beilstein Handbook Reference)
P-CYMENE-2-CARBOXYLIC ACID, 3-HYDROXY
DTXCID30125770
6-methyl-3-isopropyl-salicylic acid
Benzoic acid, 2-hydroxy-6-methyl-3-(1-methylethyl)-(9CI)
inchi=1/c11h14o3/c1-6(2)8-5-4-7(3)9(10(8)12)11(13)14/h4-6,12h,1-3h3,(h,13,14
2-hydroxy-6-methyl-3-propan-2-ylbenzoic acid
ORTHOTHYMOTINIC ACID
UNII-GF566F3K7L
o-Thymotinsaure
MFCD00020270
Spectrum_001420
Spectrum2_000438
Spectrum3_001779
Spectrum4_000088
Spectrum5_001130
BSPBio_003277
KBioGR_000356
KBioSS_001900
MLS002207117
SCHEMBL503619
SPBio_000456
CHEMBL1905986
CHEBI:93677
KBio2_001900
KBio2_004468
KBio2_007036
KBio3_002778
NSC68360
NSC76970
CCG-40250
AKOS005174254
SMR001306720
DB-052656
CS-0327006
NS00007483
G67833
2-hydroxy-6-methyl-3-(propan-2-yl)benzoic acid
2-Hydroxy-3-isopropyl-6-methylbenzoic acid, 98%
BRD-K95788524-001-02-4
Q27165372