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3-Hydroxytoluamide

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Identification
Molecular formula
C8H9NO2
CAS number
6402-23-9
IUPAC name
2-hydroxy-3-methyl-benzamide
State
State

At room temperature, 3-Hydroxytoluamide is typically found in a solid state. It holds a crystalline form, which ensures that it maintains its shape unless heated to its melting point or dissolved in a solvent.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
151.16g/mol
Molar mass
151.1630g/mol
Density
1.1601g/cm3
Appearence

3-Hydroxytoluamide is a white crystalline solid. It often appears in a pure, dry state, displaying a crystalline structure that is characteristic of many small organic molecules.

Comment on solubility

Solubility of 2-hydroxy-3-methyl-benzamide

2-hydroxy-3-methyl-benzamide, with a molecular formula of C9H11NO2, exhibits specific solubility properties that can be both intriguing and significant in various chemical contexts. Understanding its solubility behavior is key for applications such as pharmaceuticals and environmental chemistry.

Solubility Characteristics

  • Water Solubility: This compound demonstrates moderate solubility in water due to the presence of the hydroxyl group (-OH) which can form hydrogen bonds with water molecules.
  • Solvent Compatibility: 2-hydroxy-3-methyl-benzamide is more soluble in organic solvents such as ethanol and acetone, which are often used as solvents in chemical reactions involving this compound.
  • Influencing Factors: The solubility may be affected by temperature and pH. Generally, increasing temperature will enhance solubility in most solvents.
  • Practical Implications: The solubility profile is crucial for its applications in drug formulation, as it affects bioavailability and therapeutic efficacy.

In conclusion, the solubility of 2-hydroxy-3-methyl-benzamide varies significantly depending on the solvent and conditions. Understanding these nuances allows chemists to effectively utilize this compound in practical applications.

Interesting facts

Exploring 2-Hydroxy-3-methyl-benzamide

2-Hydroxy-3-methyl-benzamide, often abbreviated as 2-HO-3-MB, is an intriguing compound that has garnered interest in various fields of chemistry and biochemistry. Here are some captivating facts about this compound:

  • Functional Group Diversity: This compound contains both a hydroxyl group (-OH) and an amide group (-C(O)NH2), allowing it to participate in a variety of chemical reactions and form different derivatives.
  • Bioactivity: Compounds with similar structures often exhibit biological activities, including anti-inflammatory and analgesic properties. Researchers are keen to investigate whether 2-HO-3-MB shares these properties and can be utilized in medicinal chemistry.
  • Role in Organic Synthesis: 2-Hydroxy-3-methyl-benzamide may serve as an important intermediate in the synthesis of other organic compounds, contributing to the development of pharmaceuticals and agrochemicals.
  • Researchers' Interest: Certain studies have pointed towards its potential as a building block in the design of more complex molecules, attracting the attention of both organic chemists and materials scientists.
  • Systematic Nomenclature: The nomenclature reflects its structure, with the "2-hydroxy" indicating the position of the hydroxyl group on the benzene ring, and "3-methyl" denoting the methyl group that modifies the benzene's characteristics.

As a scientist or student delving into the depths of organic chemistry, understanding and exploring such compounds is vital for developing innovative solutions and enhancing our grasp of chemical interactions. Keep an eye on this compound as it may hold keys to future discoveries!

Synonyms
2,3-CRESOTAMIDE
3-Methyl-2-hydroxybenzamide
2-hydroxy-3-methylbenzamide
Cresotamide
14008-60-7
Cresotamida
Benzamide, 2-hydroxy-3-methyl-
Cresotamide [INN:DCF]
5748P7L6IT
MFCD00242811
Midalgyl
3-Methylsalicylamide
Cresotamidum
Salicylamide, 3-methyl-
Cresotamidum [INN-Latin]
Cresotamida [INN-Spanish]
EINECS 237-821-0
BRN 1101526
Cresotamid
UNII-5748P7L6IT
Hydroxy-2 methyl-3 benzene carbonamide-1 [French]
Hydroxy-2 methyl-3 benzene carbonamide-1
CRESOTAMIDE [INN]
CRESOTAMIDE [WHO-DD]
2-10-00-00132 (Beilstein Handbook Reference)
2-hydroxy-3-methyl-benzamide
MLS006011506
SCHEMBL1451463
SCHEMBL1806782
SCHEMBL1806785
CHEMBL2104183
DTXSID40161225
NWULWVPYPIRXAU-UHFFFAOYSA-N
AC4144
AKOS000207605
MB01077
SMR004703283
SY033355
CS-0308644
NS00021639
EN300-1263644
SR-01000944831
SR-01000944831-1
Q27261464
Z68590334