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o-Cresotinic acid

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Identification
Molecular formula
C8H8O3
CAS number
649-44-3
IUPAC name
2-hydroxy-3-methyl-benzoic acid
State
State

The compound is typically found in a solid state at room temperature.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
355.00
Boiling point (Kelvin)
628.15
General information
Molecular weight
166.17g/mol
Molar mass
166.1730g/mol
Density
1.4360g/cm3
Appearence

The compound appears as a white to pale yellow crystalline powder.

Comment on solubility

Solubility of 2-hydroxy-3-methyl-benzoic acid

2-hydroxy-3-methyl-benzoic acid, commonly known as salicylic acid, exhibits fascinating solubility characteristics that are integral to its applications in various fields.

This compound is largely soluble in:

  • Alcohols: Particularly in ethanol and methanol, where it dissolves quite readily.
  • Aqueous Solutions: It is moderately soluble in water at room temperature, which can be enhanced with temperature increase.
  • Organic Solvents: Salicylic acid has good solubility in many organic solvents, making it versatile for various reactions and formulations.

However, it is essential to note that:

  • pH Sensitivity: Its solubility can be affected by the pH of the solution. In acidic conditions, it may be less soluble compared to neutral or basic environments.
  • Concentration Limits: At higher concentrations, saturation can occur, resulting in decreased solubility.

In conclusion, the solubility of 2-hydroxy-3-methyl-benzoic acid is a key factor that influences its effectiveness in different applications. As described, it is a compound whose fate in solution can be influenced by a variety of factors, making it truly fascinating.

Interesting facts

Interesting Facts about 2-Hydroxy-3-Methyl-Benzoic Acid

2-Hydroxy-3-methyl-benzoic acid, also known as salicylic acid, is a fascinating compound that plays a crucial role in both nature and various industries. Here are some intriguing insights about this compound:

  • Aspirin's Predecessor: Salicylic acid is the precursor to the widely-used pain reliever acetylsalicylic acid, commonly known as aspirin. It was originally derived from the bark of the willow tree, making it one of the earliest forms of pain relief.
  • Natural Source: This compound is naturally found in various plants, including willow, meadowsweet, and birch. The name "salicylic" is derived from the Latin word "salix," meaning willow.
  • Medical Uses: Beyond its historical significance, salicylic acid is a key ingredient in many skincare products due to its anti-inflammatory and exfoliating properties. It is particularly effective in treating acne and psoriasis.
  • Biochemical Importance: In plants, salicylic acid plays a critical role in the defense mechanism against pathogens. It is involved in the signaling pathways that activate plant defenses, making it essential for their survival.
  • Flavoring and Preservation: This compound is also utilized in food applications. It can act as a preservative and has been used to enhance the flavor of certain products.

With its rich history and wide range of applications, 2-hydroxy-3-methyl-benzoic acid continues to be of great interest to both scientists and industries alike.

Synonyms
3-Methylsalicylic acid
83-40-9
2-Hydroxy-3-methylbenzoic acid
Hydroxytoluic acid
O-CRESOTIC ACID
o-Cresotinic acid
2,3-Cresotic acid
Cresotic acid
2-Hydroxy-m-toluic acid
Benzoic acid, 2-hydroxy-3-methyl-
o-Homosalicylic acid
2,3-Cresotinic acid
Cresotinic acid
Homosalicylic acid
3-Methyl-2-hydroxybenzoic acid
Hydroxytoluylsaeure
3-cresotinic acid
Acido hidroxitoluico
Acide hydroxytoluique
3-Methylsalicylsaeure
3-MS
Acido ortocresotinico
Acidum hydroxitoluicum
Acidum hydroxytoluicum
3-methyl salicylic acid
Cresotic acid, o-
beta-Cresotinic acid
NSC 17561
Hydroxytoluic acid [INN:BAN]
Acido 3-ossi-5-metil-benzoico
Acido ortocresotinico [Italian]
3-Methylsalicylate
Acide hydroxytoluique [INN-French]
Acido hidroxitoluico [INN-Spanish]
Acidum hydroxytoluicum [INN-Latin]
EINECS 201-473-8
ZH3HEY032H
MFCD00002448
NSC-17561
BRN 2086811
3 MS
Acido 3-ossi-5-metil-benzoico [Italian]
DTXSID9038686
CHEBI:20141
AI3-15025
.beta.-Cresotinic acid
O-CRESOTIC ACID [MI]
CHEMBL448399
DTXCID7018686
HYDROXYTOLUIC ACID [INN]
4-10-00-00601 (Beilstein Handbook Reference)
HYDROXYTOLUIC ACID [WHO-DD]
NCGC00095792-01
2-hydroxy-3-methylbenzoate
Acide hydroxytoluique (INN-French)
Acido hidroxitoluico (INN-Spanish)
Acidum hydroxytoluicum (INN-Latin)
CAS-83-40-9
UNII-ZH3HEY032H
o-Kresotinsaure
oCresotic acid
beta-cresotinate
oCresotinic acid
3-Cresotinate
2-hydroxy-3-methyl benzoic acid
hydroxytoluic-acid
2,3-cresotinate
oHomosalicylic acid
2,3-cresotate
2,3Cresotic acid
3Methylsalicylsaeure
2Hydroxymtoluic acid
2,3Cresotinic acid
2-hydroxy-m-toluate
3-Metylsalicylic acid
3-Methylsalycilic acid
3-methylsalicyclic acid
Spectrum_000437
3-methyl-salicylic acid
SpecPlus_000905
45848-87-1
Spectrum2_000151
Spectrum3_000757
Spectrum4_000789
Spectrum5_000741
bmse000620
2Hydroxy3methylbenzoic acid
3-methyl-2-hydroxybenzoate
3Methyl2hydroxybenzoic acid
2-hydroxy-3-methyl-benzoate
Oprea1_525952
SCHEMBL25756
BSPBio_002374
KBioGR_001238
KBioSS_000917
SPECTRUM212064
MLS002207190
2-Hydroxy-3-methylbenzoicacid
Benzoic acid, 2hydroxy3methyl
DivK1c_007001
SPBio_000282
3-Methylsalicylic acid, 97%
KBio1_001945
KBio2_000917
KBio2_003485
KBio2_006053
KBio3_001594
MSK2656
NSC1772
HMS3264E18
Pharmakon1600-00212064
HY-B1399
NSC-1772
NSC17561
NSC50796
Tox21_111523
BBL023681
BDBM50275341
CCG-38951
NSC-50796
NSC755829
STK426344
AKOS000119923
Tox21_111523_1
AC-7749
CS-4909
FM25563
FS-3191
NSC-755829
NCGC00095792-02
NCGC00095792-03
SMR000112084
SY014329
SBI-0052675.P002
NS00007358
EN300-17315
D70635
AB00053143_02
SR-01000872738
SR-01000872738-1
BRD-K75608666-001-02-6
BRD-K75608666-001-03-4
BRD-K75608666-001-08-3
Q27109285
Z56917421
2-Hydroxy-3-methylbenzoic acid;2,3-Cresotic acid;b-Cresotinic acid
201-473-8