Skip to main content

3-Nitrosalicylic acid

ADVERTISEMENT
Identification
Molecular formula
C7H5NO5
CAS number
575-19-3
IUPAC name
2-hydroxy-3-nitro-benzoic acid
State
State

The compound is a solid at room temperature, typically found as yellow crystals.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
183.12g/mol
Molar mass
183.1160g/mol
Density
1.6300g/cm3
Appearence

3-Nitrosalicylic acid is an organic compound that appears as a yellow crystalline solid. It is commonly observed in a powder or granular crystalline form.

Comment on solubility

Solubility of 2-hydroxy-3-nitro-benzoic acid

2-hydroxy-3-nitro-benzoic acid, also known as salicylic acid nitro derivative, showcases interesting solubility properties that can be influenced by various factors. Its solubility can generally be described as follows:

  • Water solubility: This compound has moderate solubility in water. Its ability to dissolve in water may be attributed to the presence of the -OH (hydroxyl) group, which can form hydrogen bonds with water molecules.
  • Solvent effects: Besides water, it displays varying solubility in organic solvents like ethanol and acetone, making it more versatile in different chemical environments.
  • Temperature dependency: The solubility of 2-hydroxy-3-nitro-benzoic acid typically increases with temperature, which is a common characteristic for many organic acids.

As with many compounds, the solubility is influenced by factors such as:

  • The presence of other ionic or polar species in the solution
  • pH levels of the solvent
  • Concentration gradient in solution

In conclusion, understanding the solubility of 2-hydroxy-3-nitro-benzoic acid is critical for its applications in various fields, including pharmaceuticals and materials science. A general rule to remember is that like dissolves like, meaning its solubility will be better in solvents that share similar polar characteristics.

Interesting facts

Interesting Facts about 2-Hydroxy-3-nitro-benzoic Acid

2-Hydroxy-3-nitro-benzoic acid, often referred to by its alternative name salicylic acid, is a fascinating compound with various applications and historical significance in the field of chemistry and medicine. Here are some intriguing aspects:

  • Historical Significance: Salicylic acid has been used for centuries. Its name is derived from the Latin word salis, meaning willow, as it was originally derived from willow bark extracts. This natural source was used by ancient civilizations for pain relief.
  • Medicinal Properties: It is best known for its role in the synthesis of acetylsalicylic acid (commonly known as aspirin), which revolutionized pain management and anti-inflammatory therapies.
  • Applications in Skincare: Beyond its use in pharmaceuticals, 2-hydroxy-3-nitro-benzoic acid is a key ingredient in numerous skincare products due to its ability to exfoliate and improve skin conditions such as acne and psoriasis.
  • Antimicrobial Activity: This compound has demonstrated antibacterial and antifungal properties, making it a subject of research for developing new antimicrobial agents.
  • Green Chemistry: In recent years, researchers have focused on more sustainable methods of synthesizing salicylic acid, underscoring its relevance in the context of green chemistry and environmental sustainability.

As a student or scientist, exploring the multifaceted applications and historical background of 2-hydroxy-3-nitro-benzoic acid can provide a rich understanding of its impact on both science and everyday life. Its journey from ancient herbal remedies to modern-day pharmaceuticals reflects the evolving relationship between chemistry and health.

Synonyms
3-Nitrosalicylic acid
2-Hydroxy-3-nitrobenzoic acid
85-38-1
Salicylic acid, 3-nitro-
Benzoic acid, 2-hydroxy-3-nitro-
2-hydroxy-3-nitro-benzoic acid
NSC 182
BRN 2213132
UNII-47661X4L2C
AI3-08930
NSC-182
Salicylic acid, 3-nitro
MFCD00024240
47661X4L2C
DTXSID80234048
3-NITROSALICYLIC ACID [MI]
4-10-00-00228 (Beilstein Handbook Reference)
MESALAZINE IMPURITY R [EP IMPURITY]
3-Nitrosalicylicacid
MESALAZINE IMPURITY R (EP IMPURITY)
Salicylic acid, 3-nitro- (7CI,8CI); 2-Hydroxy-3-nitrobenzoic acid; 3-Nitrosalicylic acid; NSC 182
3-Nitro-salicylsaure
3-nitrosalicyclic acid
WLN: WNR BQ CVQ
SCHEMBL71887
NSC182
DTXCID80156539
STK688148
AKOS000282179
FN26344
HY-W039726
2-Hydroxy-3-nitrobenzoic acid;NSC 182
AS-46787
SY107293
DB-031391
3-Nitrosalicylic acid, >=99.0% (HPLC)
CS-0097789
N0251
EN300-98791
F10498
AE-562/40897208
Q27259019
Z1255465064
628-816-8