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Salicylic acid

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Identification
Molecular formula
C7H6O3
CAS number
69-72-7
IUPAC name
2-hydroxy-3-phenyl-benzoic acid
State
State

Salicylic acid is a solid at room temperature. It is typically found in the form of crystalline powder or as needle-like crystals. The compound is stable under ordinary conditions, though it should be kept clear of excessive heat, moisture, and light to prevent decomposition.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
211.00
Boiling point (Kelvin)
484.15
General information
Molecular weight
138.12g/mol
Molar mass
138.1210g/mol
Density
1.4430g/cm3
Appearence

Salicylic acid typically appears as colorless to white, needle-like crystals or as a crystalline powder. The crystals are quite distinctive in their needle-like structure and are often easy to identify. In powdered form, it remains white and has no significant odor. The appearance can change slightly to have a pinkish hue if exposed and aged due to partial oxidation but remains predominantly white upon storage in cool, dry conditions.

Comment on solubility

Solubility of 2-hydroxy-3-phenyl-benzoic acid

2-hydroxy-3-phenyl-benzoic acid, often referred to as a derivative of benzoic acid, exhibits notable characteristics when it comes to its solubility profile. Here are some key points regarding its solubility:

  • Solvent Dependence: The solubility of this compound can vary significantly depending on the solvent used. It is generally more soluble in organic solvents such as ethanol and methanol.
  • Water Solubility: Due to the presence of the carboxylic acid (-COOH) and hydroxyl (-OH) groups, it can exhibit limited solubility in water. However, the extent of this solubility is influenced by factors like temperature and pH.
  • Temperature Effects: Increased temperature usually enhances solubility for many organic acids, including 2-hydroxy-3-phenyl-benzoic acid. A rise in temperature may lead to greater dissolution in the available solvent.
  • pH Influence: The solubility may also be affected by the pH of the solution. For instance, at higher pH levels, the carboxylic acid group can deprotonate, leading to anionic species that are generally more soluble in aqueous environments.

In summary, while 2-hydroxy-3-phenyl-benzoic acid demonstrates a degree of solubility in various solvents, understanding its solubility behavior in specific conditions is crucial for applications in fields such as pharmaceuticals and organic synthesis. As a guiding principle, it is essential to consider solvent choice and environmental factors to achieve optimal dissolution.

Interesting facts

Interesting Facts about 2-Hydroxy-3-phenyl-benzoic Acid

2-Hydroxy-3-phenyl-benzoic acid, often referred to as a specific derivative of salicylic acid, has garnered attention due to its unique properties and applications in various fields. Here are some intriguing aspects about this compound:

  • Biochemical Relevance: Due to its hydroxy and carboxylic acid functional groups, 2-hydroxy-3-phenyl-benzoic acid exhibits important biological activities, making it useful in pharmaceutical applications, particularly in anti-inflammatory and analgesic products.
  • Antioxidant Properties: This compound has shown potential as a natural antioxidant, which can be beneficial in combating oxidative stress in living organisms.
  • Synthetic Pathways: Scientists have developed various synthetic routes to obtain this compound, showcasing its versatility and the ingenuity involved in organic synthesis. Understanding these pathways can aid in the design of new compounds with desired activities.
  • Research Interests: Current studies are exploring its role as a building block in the synthesis of more complex organic molecules, which has implications for materials science and drug development.
  • Historical Context: This compound is part of a larger family of benzoic acid derivatives, which have been explored since the early days of organic chemistry. Its study continues to yield interesting insights into the behavior of aromatic compounds.

In conclusion, 2-hydroxy-3-phenyl-benzoic acid presents a fascinating example of how a simple organic compound can play vital roles in various scientific fields, from medicinal chemistry to materials science. As research advances, we can expect to uncover even more about its potential applications and benefits.

Synonyms
3-Phenylsalicylic acid
304-06-3
2-Hydroxy-3-phenylbenzoic acid
2-hydroxybiphenyl-3-carboxylic acid
m-Phenylsalicylic acid
[1,1'-Biphenyl]-3-carboxylic acid, 2-hydroxy-
USAF DO-59
2-Hydroxy-[1,1'-biphenyl]-3-carboxylic acid
SALICYLIC ACID, 3-PHENYL-
EINECS 206-148-4
NSC 109101
BRN 2693467
(1,1'-Biphenyl)-3-carboxylic acid, 2-hydroxy-
AI3-17391
NSC-1886
3-Biphenylcarboxylic acid, 2-hydroxy-
3327W9W36P
NSC-109101
MLS002637597
CHEMBL229466
DTXSID1059787
3-10-00-01159 (Beilstein Handbook Reference)
[1, 2-hydroxy-
WLN: QVR BQ CR
3-phenylsalicylate
HBPA acid
3-Phenylsalicylsaure
MFCD00020257
2-Hydroxy-[1,1'-biphenyl]-3-carboxylicacid
SCHEMBL73041
DTXCID3038191
UNII-3327W9W36P
NSC1886
HMS3091J07
AAA30406
BBL035903
BDBM50219481
NSC109101
STL432216
AKOS009157681
FS-4696
SMR001547126
DB-068283
CS-0210316
NS00028920
P0226
D91928
2-Hydroxy[1,1'-biphenyl]-3-carboxylic acid #
EN300-2008620
3-Biphenylcarboxylic acid, 2-hydroxy-(7CI,8CI)
206-148-4
InChI=1/C13H10O3/c14-12-10(9-5-2-1-3-6-9)7-4-8-11(12)13(15)16/h1-8,14H,(H,15,16